E-GEOD-31953 - Profiling pancreatic islets from obese db/db and lean control db/+ mice

Status
Released on 22 March 2013, last updated on 2 June 2014
Organism
Mus musculus
Samples (20)
Array (1)
Protocols (7)
Description
This program addresses the molecular basis of beta-cell failure associated with the development of type 2 diabetes in the db/db mice. Specifically, which genes are differentially expressed in pancreatic islets of the db/db mice compared to the control db/+ mice? The db/db mice islets profiling data was analyzed by identifying genes that were up- and down-regulated at selected p value and fold change in the islets of db/db mice compared to the corresponding db/+ controls.
Experiment type
transcription profiling by array 
Contacts
Citation
Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers. Wang IM, Zhang B, Yang X, Zhu J, Stepaniants S, Zhang C, Meng Q, Peters M, He Y, Ni C, Slipetz D, Crackower MA, Houshyar H, Tan CM, Asante-Appiah E, O'Neill G, Luo MJ, Thieringer R, Yuan J, Chiu CS, Lum PY, Lamb J, Boie Y, Wilkinson HA, Schadt EE, Dai H, Roberts C. , Europe PMC 22806142
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-31953.idf.txt
Sample and data relationshipE-GEOD-31953.sdrf.txt
Processed data (1)E-GEOD-31953.processed.1.zip
Additional data (1)E-GEOD-31953.additional.1.zip
Array designA-GEOD-8591.adf.txt
Links