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E-GEOD-31853 - Expression data from oral squamous cell carcinoma (OSCC)-derived cell lines and normal oral keratinocytes

Status
Released on 1 September 2011, last updated on 14 September 2011
Organism
Homo sapiens
Samples (11)
Arrays (2)
Protocols (11)
Description
Oral squamous cell carcinoma (OSCC) is a lethal disease and early death usually occurs as a result of local invasion and regional lymph node metastases. We used microarrays to identify down or upregulated genes in OSCCs compared with non-malignant controls. To identify genes whose transcription is deregulated in OSCC, the gene expression profiles of eight OSCC cell lines (H-series and M9) and three primary cultures of normal oral keratinocytes (NKs) were examined using Affymetrix HG-U133A and HG-U133 Plus 2.0 arrays.
Experiment type
transcription profiling by array 
Contacts
Wenbin Wei <w.wei@bham.ac.uk>, Ian Paterson, LeeFah Yap, Max Robinson, Victor Lopes
Citation
Upregulation of Eps8 in oral squamous cell carcinoma promotes cell migration and invasion through integrin-dependent Rac1 activation. Yap LF, Jenei V, Robinson CM, Moutasim K, Benn TM, Threadgold SP, Lopes V, Wei W, Thomas GJ, Paterson IC. , PMID:19448673
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-31853.idf.txt
Sample and data relationshipE-GEOD-31853.sdrf.txt
Raw data (1)E-GEOD-31853.raw.1.zip
Processed data (1)E-GEOD-31853.processed.1.zip
Array designsA-AFFY-33.adf.txt, A-AFFY-44.adf.txt
R ExpressionSetE-GEOD-31853.eSet.r
Links