E-GEOD-31733 - Expression data from B6, Sle1b and Sle1b.BACSlamf6-H1 CD4+ T cells

Status
Released on 23 April 2013, last updated on 2 June 2014
Organism
Mus musculus
Samples (28)
Array (1)
Protocols (7)
Description
We recently showed that the Slamf6 protein isoform Slamf6-H1 markedly diminishes T cell–dependent disease upon introduction of a Slamf6-H1–expressing transgene into the lupus-prone Sle1b mouse, which lacks this isoform. In this study we purified CD4+ T cells from Sle1b, Sle1b.Slamf6-H1, or B6 mice and a global gene expression profile was analyzed. Comparison of isolated cells from three strains of mice (12wk old females) at three time points of anti-CD3 activation with three biological replicates for each group (unless indicated otherwise).
Experiment type
transcription profiling by array 
Contacts
Marton Keszei <marton.keszei@ki.se>, Cox Terhorst, Cynthia Detre, Wilson Castro
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-31733.idf.txt
Sample and data relationshipE-GEOD-31733.sdrf.txt
Raw data (1)E-GEOD-31733.raw.1.zip
Processed data (1)E-GEOD-31733.processed.1.zip
Array designA-GEOD-11180.adf.txt
Links