normalization data transformation protocol
The data were processed and normalised using quantile normalisation with BeadStudio software ID_REF = VALUE = quantile normalized Detection Pval =
array scanning protocol
Standard Illumina scanning protocol
Standard Illumina hybridization protocol
Biotinylated cRNA were prepared with the Ambion MessageAmp kit for Illumina arrays
nucleic acid extraction protocol
RNA was extracted with Trizol reagent, followed by clean-up and DNase I treatment with QIAGEN RNeasy mini kit in accordance with the prescribed protocol provided with the kit. Quality control was performed with Agilent Bioanalyser.