E-GEOD-30922 - Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
Released on 9 August 2011, last updated on 15 August 2011
Chemokines have been suggested to play a role during development of left ventricular failure, but little is known about their role during right ventricular (RV) remodeling and dysfunction. The first aim of this study was to identify chemokines which are regulated during RV pressure overload. We then hypothesized that these chemokines regulate SLRPs (small leucine-rich proteoglycans) A microarray study was performed on 5 pulmonary banded and sham operated wildype mice.
transcription profiling by array
Ståle Nygård <email@example.com>, Anne Wæhre, Geir Christensen