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E-GEOD-30531 - Expression data of A375 melanoma cells after DMSO or MLN4924 treatment from 1 hour to 24 hour

Status
Released on 9 July 2011, last updated on 20 August 2015
Organism
Homo sapiens
Samples (30)
Array (1)
Protocols (8)
Description
Microarrays were used to determine the change in gene expression of genes involved in the CDT1/NAE pathway A375 cells were grown and then incubated in the presence of either DMSO as control or 650nM MLN4924. Cells were treated for 1, 2, 4, 8, and 24 hours. RNA extraction and hybridization on Affymetrix HG-U133Plus 2.0 arrays were performed.
Experiment type
transcription profiling by array 
Contacts
Hugues Bernard <bernard@mpi.com>, Eric S Lightcap, Xiaozhen J Liu
Citation
Quantitative proteomic analysis of cellular protein modulation upon inhibition of the NEDD8-activating enzyme by MLN4924. Hua Liao, Xiaozhen J. Liu, Jonathan L. Blank, David C. Bouck, Hugues Bernard, Khristofer Garcia, Eric S. Lightcap.
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-30531.idf.txt
Sample and data relationshipE-GEOD-30531.sdrf.txt
Raw data (1)E-GEOD-30531.raw.1.zip
Processed data (1)E-GEOD-30531.processed.1.zip
Array designA-AFFY-44.adf.txt
Links