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E-GEOD-29605 - Gene expression data from chronic lymphocytic leukemia samples

Status
Released on 1 June 2011, last updated on 2 June 2014
Organism
Homo sapiens
Samples (22)
Array (1)
Protocols (6)
Description
MicroRNA-155 is frequently over-expressed in CLL and is associated with worse clinical prognosis. To understand the role of miR-155 in CLL pathogenesis, we used microarrays to identify genes that are expressed at significantly lower levels in CLLs that harbor higher levels of miR-155 expression in an attempt to determine the relevant gene targets of miR-155 in CLL. MiR-155 levels of 38 CLL samples were determined and ranked. 6 CLLs with the highest and 6 CLLs with the lowest miR-155 within the IgVH unmutated group, and 5 CLLs with the highest and 5 CLLs with the lowest miR-155 within the IgVH mutated group were selected for Affymetrix array analyses.
Experiment type
transcription profiling by array 
Contacts
Jan K Davidson-Mocada, Piali Mukherjee, Taotao Zhang, Wayne Tam
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-29605.idf.txt
Sample and data relationshipE-GEOD-29605.sdrf.txt
Raw data (2)E-GEOD-29605.raw.1.zip, E-GEOD-29605.raw.2.zip
Processed data (1)E-GEOD-29605.processed.1.zip
Array designA-AFFY-44.adf.txt
Links