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E-GEOD-28656 - Genes regulated by Nkx2-3 in human intestinal microvascular endothelial cells

Released on 15 April 2011, last updated on 26 April 2011
Homo sapiens
Samples (8)
Array (1)
Protocols (9)
Nkx2-3 is associated with inflammatory bowel disease (IBD). Nkx2-3 is expressed in microvascular endothelial cells and the muscuularis mucosa of the gastrointestinal tract. Human intestinal microvascular cells (HIMEC) are actively involved in the pathogenesis of IBD and IBD-associated microvascular dysfunction. To understand the cellular function of Nkx2-3 and its potential role underlying IBD pathogenesis, we investigated the genes regulated by Nkx2-3 in HIMEC usin cDNA microarray. 2 HIMEC lines (21B and 432) are used in thi study. For each HIMEC lines, either si-Nkx2-3 or contro vector was transfected 2 times to get biological replicates.
Experiment type
transcription profiling by array 
wei yu <>, Gail West, John P Hegarty, Wei Yu, Xi Chen
Investigation descriptionE-GEOD-28656.idf.txt
Sample and data relationshipE-GEOD-28656.sdrf.txt
Processed data (1)
Array designA-GEOD-10558.adf.txt