Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.

E-GEOD-28656 - Genes regulated by Nkx2-3 in human intestinal microvascular endothelial cells

Status
Released on 15 April 2011, last updated on 26 April 2011
Organism
Homo sapiens
Samples (8)
Array (1)
Protocols (9)
Description
Nkx2-3 is associated with inflammatory bowel disease (IBD). Nkx2-3 is expressed in microvascular endothelial cells and the muscuularis mucosa of the gastrointestinal tract. Human intestinal microvascular cells (HIMEC) are actively involved in the pathogenesis of IBD and IBD-associated microvascular dysfunction. To understand the cellular function of Nkx2-3 and its potential role underlying IBD pathogenesis, we investigated the genes regulated by Nkx2-3 in HIMEC usin cDNA microarray. 2 HIMEC lines (21B and 432) are used in thi study. For each HIMEC lines, either si-Nkx2-3 or contro vector was transfected 2 times to get biological replicates.
Experiment type
transcription profiling by array 
Contacts
wei yu <weiyu@hmc.psu.edu>, Gail West, John P Hegarty, Wei Yu, Xi Chen
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-28656.idf.txt
Sample and data relationshipE-GEOD-28656.sdrf.txt
Processed data (1)E-GEOD-28656.processed.1.zip
Array designA-GEOD-10558.adf.txt
Links