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E-GEOD-27533 - IL-17 downregulates filaggrin and affects epidermal barrier function gene expression; potential role in the pathogenesis of atopic eczema

Status
Released on 1 November 2012, last updated on 8 November 2012
Organism
Homo sapiens
Samples (6)
Array (1)
Protocols (8)
Description
Genome-wide analysis of gene expression after stimulation with cytokines to assess the main processes, molecular functions and cellular components affected as well as genes related to skin barrier function. HaCaT cells were exposed to IL-17A (200ng/ml) for 12h. The cells were lysed, total RNA was extracted and microarray study was performed on Illumina HT12 platform.
Experiment type
transcription profiling by array 
Contacts
Stephen Taylor <stephen.taylor@imm.ox.ac.uk>, Danuta Gutowska-Owsiak, Graham S Ogg
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-27533.idf.txt
Sample and data relationshipE-GEOD-27533.sdrf.txt
Processed data (1)E-GEOD-27533.processed.1.zip
Additional data (1)E-GEOD-27533.additional.1.zip
Array designA-GEOD-10558.adf.txt
Links