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E-GEOD-26193 - Control of oxidative stress by miRNA and impact on ovarian tumorigenesis

Status
Released on 1 November 2011, last updated on 14 November 2011
Organism
Homo sapiens
Samples (107)
Array (1)
Protocols (6)
Description
Transcriptome analysis of high-grade human ovarian adenocarcinomas. The hypothesis tested in the present study was that two reciprocal pathways, namely oxidative stress response and fibrosis, enable to build a hierarchical cluster of ovarian patients. Ovarian human tumor samples from Institut Curie were analysed on human genome U133 plus 2.0 array (Affymetrix). Microarray analysis was performed using Partek Genomic Suite software and transcriptomic data were normalized using GCRMA algorithm. Probes from oxidative stress response and fibrosis defined by Ingenuity software were used to build a hierarchical cluster of ovarian patients.
Experiment type
transcription profiling by array 
Contacts
Fatima Mechta-Grigoriou <fatima.mechta-grigoriou@curie.fr>, Bogdan Mateescu, Jean-Philippe Meyniel, Luciana Batista, Odette Mariani, Paul H Cottu, Xavier Sastre-Garau
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-26193.idf.txt
Sample and data relationshipE-GEOD-26193.sdrf.txt
Raw data (3)E-GEOD-26193.raw.1.zip, E-GEOD-26193.raw.2.zip, E-GEOD-26193.raw.3.zip
Processed data (1)E-GEOD-26193.processed.1.zip
Array designA-AFFY-44.adf.txt
R ExpressionSetE-GEOD-26193.eSet.r
Links