Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.

E-GEOD-25182 - tTA/TDP Mice Expression Array

Status
Submitted on 8 November 2010, released on 10 November 2010, last updated on 10 June 2011
Organism
Mus musculus
Samples (21)
Array (1)
Protocols (6)
Description
Transgenic (Tg) mice expressing nuclear or cytoplasmic human TDP-43 were generated. Tg mice had motor spasticity and forebrain neurodegeneration. Human TDP-43 reduced mouse TDP-43 in nuclei of affected neurons. Tg mice showed alterations in transcripts related to chromatin assembly. Cerebral cortex from 21 transgenic mice and controls were assayed after two weeks off doxycyline diet as described in Igaz et al.
Experiment type
transcription profiling by array 
Contacts
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-25182.idf.txt
Sample and data relationshipE-GEOD-25182.sdrf.txt
Raw data (1)E-GEOD-25182.raw.1.zip
Processed data (1)E-GEOD-25182.processed.1.zip
Array designA-AFFY-36.adf.txt
R ExpressionSetE-GEOD-25182.eSet.r
Links