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E-GEOD-24687 - C-peptide regulates early transcription in rat proximal tubular cells
Released on 26 July 2011, last updated on 16 August 2011
C-peptide exerts beneficial effects on glomerular hyperfiltration in type I diabetic patients. As C-peptide localizes to the nucleus, we investigated the transcriptional activities of C-peptide in proximal tubular cells isolated from diabetic rats. Two groups of proximal tubular cells isolated from type I diabetic rats: 1 treated with C-peptide, and 1 untreated. 2-3 replicates per group.
transcription profiling by array
Emma Lindahl <email@example.com>, Eli El Agha, Fredrik Palm, Hans Jörnvall, Karin Dahlman-Wright, Lina Nordquist, Malou Friederich, Patrick Müller
Early transcriptional regulation by C-peptide in freshly isolated rat proximal tubular cells. Lindahl E, Nordquist L, Müller P, El Agha E, Friederich M, Dahlman-Wright K, Palm F, Jörnvall H. , PMID:21618400