Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-24514 - Expression data from human MSI colorectal cancer and normal colonic mucosa
Released on 1 March 2011, last updated on 2 June 2014
Microsatellite instability (MSI), caused by defective mismatch repair, is observed in a subset of colorectal cancers (CRCs). We evaluated somatic mutations in microsatellite repeats of genes chosen based on reduced expression in MSI CRC and existence of a coding mononucleotide repeat. Expression profiling of 34 MSI colorectal cancers and 15 normal colonic mucosas was performed in 2002. Comparison of malignant and healthy tissue.
transcription profiling by array
Pia Vahteristo <firstname.lastname@example.org>, Diego Arango, Lauri A Aaltonen, Pia Alhopuro, Torben F Ørntoft
Candidate driver genes in microsatellite-unstable colorectal cancer. Alhopuro P, Sammalkorpi H, Niittymï¿½ki I, Bistrï¿½m M, Raitila A, Saharinen J, Nousiainen K, Lehtonen HJ, Heliï¿½vaara E, Puhakka J, Tuupanen S, Sousa S, Seruca R, Ferreira AM, Hofstra RM, Mecklin JP, Jï¿½rvinen H, Ristimï¿½ki A, Orntoft TF, Hautaniemi S, Arango D, Karhu A, Aaltonen LA. , PMID:21544814