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E-GEOD-22931 - Transcript profiling in the liver of piglets fed carnitine

Status
Released on 15 July 2010, last updated on 10 June 2011
Organism
Sus scrofa
Samples (4)
Array (1)
Protocols (8)
Description
Carnitine is a water soluble quaternary amine which is essential for normal function of all tissues. Besides improving performance characteristics of livestock animals carnitine has attracted scientific interest due to several health-related effects, like protection against neurodegeneration, mitochondrial decay, and oxidative stress, improvement of glucose tolerance and insulin sensitivity as well as reduction of hepatic steatosis. To gain insight into mechanisms through which carnitine exerts its beneficial metabolic effects, we fed piglets either a control or a carnitine supplemented diet, and analyzed the transcriptome in the liver, which plays a central role in whole body metabolism. Total RNA was isolated from pig liver samples for hybridization on Affymetrix GeneChip porcine genome arrays. Two RNA pools, each for the control group and the carnitine group, were used. Each RNA pool comprised RNA from 4 pigs.
Experiment type
transcription profiling by array 
Contacts
Steffen Priebe <steffen.priebe@hki-jena.de>, Holger Kluge, Janine Keller, Klaus Eder, Reinhard Guthke, Robert Ringseis
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-22931.idf.txt
Sample and data relationshipE-GEOD-22931.sdrf.txt
Raw data (1)E-GEOD-22931.raw.1.zip
Processed data (1)E-GEOD-22931.processed.1.zip
Array designA-AFFY-75.adf.txt
Links