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E-GEOD-22759 - Expression data from cell lines originating from patients with multiple myeloma, plasmacytoma and diffuse large B-cell lymphoma

Status
Released on 30 April 2011, last updated on 2 June 2014
Organism
Homo sapiens
Samples (18)
Array (1)
Protocols (8)
Description
A predictive gene list for response to high dose melphalan therapy in patients diagnosed with multiple myeloma is generated by combining results from dose response experiments and microarray data using a B-cell line panel and the introduction of multivariate regression techniques. 18 malignant B-cell lines were analyzed by gene expression microarrays and screened for melphalan median dose dependent growth inhibition. Results are used to build a predictive gene list for response to high dose melphalan therapy in multiple myeloma.
Experiment type
transcription profiling by array 
Contacts
Martin Boegsted <martin.boegsted@rn.dk>, Alexander Schmitz, Anne Bukh, Hans E Johnsen, Johanne M Holst, Karen Dybkaer, Kirsten Fogd, Mette Nyegaard, Steffen Falgreen, Suzette Sørensen
Citation
Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines. Boegsted M, Holst JM, Fogd K, Falgreen S, S�rensen S, Schmitz A, Bukh A, Johnsen HE, Nyegaard M, Dybkaer K. , PMID:21559449
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-22759.idf.txt
Sample and data relationshipE-GEOD-22759.sdrf.txt
Raw data (1)E-GEOD-22759.raw.1.zip
Processed data (1)E-GEOD-22759.processed.1.zip
Array designA-AFFY-44.adf.txt
Links