Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-22759 - Expression data from cell lines originating from patients with multiple myeloma, plasmacytoma and diffuse large B-cell lymphoma
Released on 30 April 2011, last updated on 2 June 2014
A predictive gene list for response to high dose melphalan therapy in patients diagnosed with multiple myeloma is generated by combining results from dose response experiments and microarray data using a B-cell line panel and the introduction of multivariate regression techniques. 18 malignant B-cell lines were analyzed by gene expression microarrays and screened for melphalan median dose dependent growth inhibition. Results are used to build a predictive gene list for response to high dose melphalan therapy in multiple myeloma.
transcription profiling by array
Martin Boegsted <email@example.com>, Alexander Schmitz, Anne Bukh, Hans E Johnsen, Johanne M Holst, Karen Dybkaer, Kirsten Fogd, Mette Nyegaard, Steffen Falgreen, Suzette Sørensen
Generation of a predictive melphalan resistance index by drug screen of B-cell cancer cell lines. Boegsted M, Holst JM, Fogd K, Falgreen S, Sï¿½rensen S, Schmitz A, Bukh A, Johnsen HE, Nyegaard M, Dybkaer K. , PMID:21559449