Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-22448 - Gene expression data from wild-type and Nlrc5 knockout GM-CSF induced bone marrow dendritic cells infected with Newcastle Disease virus
Released on 22 December 2010, last updated on 27 March 2012
Nlrc5 is encoding a Nod-like receptor protein NLRC5/NOD27. To check the involvement of Nlrc5 in antiviral response, we examined gene expression profile in wild-type and Nlrc5 knockout GM-CSF bone marrow macrophage with using microarrays. Bone marrow cells were cultured with GM-CSF and harvested on day 6. The induced dendritic cells were then stimulated with NDV at moi 1, collected at 0, 2, and 4 hours after infection. Total RNA was extracted and subjected to microarray experiment according to manufactures' instructions.
transcription profiling by array
Yutaro Kumagai <email@example.com>, Himanshu Kumar, Shizuo Akira, Taro Kawai
NLRC5 Deficiency Does Not Influence Cytokine Induction by Virus and Bacteria Infections. Kumar H, Pandey S, Zou J, Kumagai Y, Takahashi K, Akira S, Kawai T. , PMID:21148033