Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-20602 - Human nephrosclerosis triggers a hypoxia-related glomerulopathy
Released on 30 March 2010, last updated on 6 November 2020
Expression data from microdissected glomeruli to examine the role of hypoxia in glomerulosclerosis of human Nephrosclerosis (NSC). Human Kidney biopsies of patients with NSC (n=14) and TN (n=4) were selected for RNA extraction and hybridization on Affymetrix microarrays. Gene expression data was then analysed using Genepattern and Genomatix software suites which revealed that CXCR4/CXCL12 plays a role in human NSC and therefore indicate that hypoxia contributes to glomerular damage in NSC.
transcription profiling by array
Preethi Sankaranarayanan <firstname.lastname@example.org>, Matthias A Neusser, Matthias Kretzler
Human nephrosclerosis triggers a hypoxia-related glomerulopathy. Neusser MA, Lindenmeyer MT, Moll AG, Segerer S, Edenhofer I, Sen K, Stiehl DP, Kretzler M, Gröne HJ, Schlöndorff D, Cohen CD. , PMID:20019191