Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-20575 - Transcription profiling by array of mouse embryonic and induced pluripotent stem cells
Released on 27 May 2010, last updated on 1 May 2014
Pluripotent cells can be derived from somatic cells by either overexpression of defined transcription factors (resulting in induced pluripotent stem cells (iPSCs)) or by nuclear transfer or cloning (resulting in NT-ESCs). To determine whether cloning further reprograms iPSCs, we used iPSCs as donor cells in nuclear transfer experiments. An iPSC clone derived from tail-tip fibroblasts using adenoviral vectors was used as donor cell in nuclear transfer experiments. RNA was isolated from both parental iPSC clone and derivative NT-ESCs lines and analyzed.
transcription profiling by array
Matthias Stadtfeld <firstname.lastname@example.org>, Konrad Hochedlinger
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Stadtfeld M, Apostolou E, Akutsu H, Fukuda A, Follett P, Natesan S, Kono T, Shioda T, Hochedlinger K. , PMID:20418860