Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.

E-GEOD-20376 - Gene expression and SNP profiling discriminates chromophobe renal cell carcinoma and oncocytoma

Status
Released on 2 February 2011, last updated on 27 January 2013
Organism
Homo sapiens
Samples (28)
Arrays (2)
Protocols (6)
Description
Gene expression profiles, high-throughput SNP genotyping, and pathway analysis effectively distinguish chRCC from oncocytoma.  We have generated a novel transcript predictor that is able to discriminate between the two entities accurately, and which has been validated both in an internal and an independent data-set, implying generalizability.  A cytogenetic alteration, loss of chromosome 1p, common to renal oncocytoma and chRCC has been identified, providing the opportunities for identifying novel tumor suppressor genes and we have identified a series of immunohistochemical markers that are clinically useful in discriminating chRCC and oncocytoma. Oncocytoma and Chromophobe RCC samples - SNP chip analysis
Experiment type
genotyping by array 
Contacts
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-20376.idf.txt
Sample and data relationshipE-GEOD-20376.sdrf.txt
Raw data (2)E-GEOD-20376.raw.1.zip, E-GEOD-20376.raw.2.zip
Processed data (1)E-GEOD-20376.processed.1.zip
Array designsA-AFFY-69.adf.txt, A-AFFY-70.adf.txt
Links