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E-GEOD-20376 - Gene expression and SNP profiling discriminates chromophobe renal cell carcinoma and oncocytoma

Released on 2 February 2011, last updated on 27 January 2013
Homo sapiens
Samples (28)
Arrays (2)
Protocols (6)
Gene expression profiles, high-throughput SNP genotyping, and pathway analysis effectively distinguish chRCC from oncocytoma.  We have generated a novel transcript predictor that is able to discriminate between the two entities accurately, and which has been validated both in an internal and an independent data-set, implying generalizability.  A cytogenetic alteration, loss of chromosome 1p, common to renal oncocytoma and chRCC has been identified, providing the opportunities for identifying novel tumor suppressor genes and we have identified a series of immunohistochemical markers that are clinically useful in discriminating chRCC and oncocytoma. Oncocytoma and Chromophobe RCC samples - SNP chip analysis
Experiment type
genotyping by array 
Investigation descriptionE-GEOD-20376.idf.txt
Sample and data relationshipE-GEOD-20376.sdrf.txt
Raw data (2),
Processed data (1)
Array designsA-AFFY-69.adf.txt, A-AFFY-70.adf.txt