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E-GEOD-20198 - ATF3 is a positive regulator of human IFN gene expression

Status
Submitted on 4 February 2010, released on 11 April 2010, last updated on 27 March 2012
Organism
Homo sapiens
Samples (12)
Array (1)
Protocols (8)
Description
The aim of this study was to identify genes regulated by IL-12, IL-18 and IFN-alpha during early differentiation of human Th1 cells Human cord blood CD4+ T cells were activated via TCR and cultured in the presence of IL-12, IFN-alpha or IL-12+IL-18. Cytokine induced gene expression was compared to activation only after 2h, 6h or 48h of cell culture. 12 samples were analyzed in total.
Experiment type
transcription profiling by array 
Contacts
Sanna Filén, Anne West, Eleanor Coffey, Emmi Ylikoski, Helena Ahlfors, Joel Nyström, Kanury V Rao, Mari Björkman, Omid Rasool, Riitta Lahesmaa, Subhash Tripathi
Citation
Activating Transcription Factor 3 Is a Positive Regulator of Human IFNG Gene Expression. Filén S, Ylikoski E, Tripathi S, West A, Björkman M, Nyström J, Ahlfors H, Coffey E, Rao KV, Rasool O, Lahesmaa R.
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-20198.idf.txt
Sample and data relationshipE-GEOD-20198.sdrf.txt
Raw data (1)E-GEOD-20198.raw.1.zip
Processed data (1)E-GEOD-20198.processed.1.zip
Array designA-AFFY-33.adf.txt
R ExpressionSetE-GEOD-20198.eSet.r
Links