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E-GEOD-17902 - Titanium dioxide nanoparticles exposure

Released on 22 December 2010, last updated on 2 May 2014
Pimephales promelas
Samples (56)
Array (1)
Protocols (7)
This project utilized oligonucleotide microarrays to examine gene expression patterns in adult male fathead minnows (Pimephales promelas) exposed to a common nanomaterial, titanium dioxide (TiO2, stearate-coated particles, MT-100TV®). We exposed adult male fathead minnows for 96 hr to three doses (0, 1, and 10 mg/L nominal) of TiO2 under static renewal conditions. TiO2 is stearate coated, 15 nm particle size. Three-condition experiment: high dose, controls (untreated, low dose). Three tissues: liver, gill, brain. Biological replicates: 4 control replicates, 4 low dose, 4 high dose for gill and liver. One array for brain control and low dose; and 2 arrays for brain high dose. Contributor: Johnson & Johnson Worldwide Envrionmental
Experiment type
transcription profiling by array 
Investigation descriptionE-GEOD-17902.idf.txt
Sample and data relationshipE-GEOD-17902.sdrf.txt
Raw data (1)
Processed data (1)
Array designA-GEOD-7342.adf.txt
R ExpressionSetE-GEOD-17902.eSet.r