Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-17705 - Endocrine Sensitivity Index Validation Dataset
Released on 13 August 2010, last updated on 27 March 2012
Validation dataset of 298 ER-positive patients treated with tamoxifen for 5 years. All patients in this dataset have ER+ breast cancer and were uniformly treated with tamoxifen for 5 years. The objective of the study was to correlate levels of genomic markers to outcomes (relapse free survival) in this cohort of uniformly treated patients. Tissue samples were processed and profiled by two different labs (MD Anderson Cancer Center and Jules Bordet Institute).
transcription profiling by array
Christos Hatzis, Christos Sotiriou, Fabrice Andre, Guenter Daxenbichler, Peter Regitnig, W F Symmans
Genomic index of sensitivity to endocrine therapy for breast cancer. Symmans WF, Hatzis C, Sotiriou C, Andre F, Peintinger F, Regitnig P, Daxenbichler G, Desmedt C, Domont J, Marth C, Delaloge S, Bauernhofer T, Valero V, Booser DJ, Hortobagyi GN, Pusztai L. , PMID:20697068