E-GEOD-17385 - Transcription profiling of human multiple myeloma cells ( MM1.S) cells with control or beta-catenin knockdown
Released on 15 September 2009, last updated on 4 September 2015
MM1.S cells stably transduced with control or beta-catenin shRNA were established. Total RNA was isolated from 5x 10^6 cells of each in triplicate. Experiment Overall Design: Comparative gene expression profiling in multiple myeloma.
transcription profiling by array, unknown experiment type
Aurora kinase A is a target of Wnt/beta-catenin involved in multiple myeloma disease progression. Dutta-Simmons J, Zhang Y, Gorgun G, Gatt M, Mani M, Hideshima T, Takada K, Carlson NE, Carrasco DE, Tai YT, Raje N, Letai AG, Anderson KC, Carrasco DR.