E-GEOD-14848 - Cadiac GATA-4 overexpression in vivo

Status
Released on 1 December 2009, last updated on 2 June 2014
Organism
Rattus norvegicus
Samples (10)
Array (1)
Protocols (6)
Description
The objective of the study was to find cardiac GATA-4 target genes by overexpressing GATA-4 transcription factor in the left ventricle by adenoviral gene transfer. Gene expression profiles three days after GATA-4 gene transfer were compared with those of Lac Z –treated animals by screening Affymetrix Rat Expression Set 230_2.0 Arrays (there are 5 samples in both group). Strain:Sprague-Dawley; Gender, Male; Weight 250-300g; tissue, left ventricle.
Experiment type
transcription profiling by array 
Contacts
Jaana Rysä <jaana.rysa@oulu.fi>, Hanna Leskinen, Heikki Ruskoaho, Mona Nemer, Olli Tenhunen
Citation
GATA-4 is an angiogenic survival factor of the infarcted heart. Rys� J, Tenhunen O, Serpi R, Soini Y, Nemer M, Leskinen H, Ruskoaho H. , Europe PMC 20200331
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-14848.idf.txt
Sample and data relationshipE-GEOD-14848.sdrf.txt
Raw data (1)E-GEOD-14848.raw.1.zip
Processed data (1)E-GEOD-14848.processed.1.zip
Array designA-AFFY-43.adf.txt
Links