E-GEOD-14848 - Cadiac GATA-4 overexpression in vivo
Released on 1 December 2009, last updated on 2 June 2014
The objective of the study was to find cardiac GATA-4 target genes by overexpressing GATA-4 transcription factor in the left ventricle by adenoviral gene transfer. Gene expression profiles three days after GATA-4 gene transfer were compared with those of Lac Z –treated animals by screening Affymetrix Rat Expression Set 230_2.0 Arrays (there are 5 samples in both group). Strain:Sprague-Dawley; Gender, Male; Weight 250-300g; tissue, left ventricle.
transcription profiling by array
Jaana Rysä <email@example.com>, Hanna Leskinen, Heikki Ruskoaho, Mona Nemer, Olli Tenhunen
GATA-4 is an angiogenic survival factor of the infarcted heart. Rysï¿½ J, Tenhunen O, Serpi R, Soini Y, Nemer M, Leskinen H, Ruskoaho H. , Europe PMC 20200331