Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-14816 - Immune Response of Immature Dendritic Cells after Infection with Human Cytomegalovirus Strain TB40E
Released on 1 August 2009, last updated on 24 July 2015
Microarray analysis and quantitative real-time PCR revealed that TB40E infection of DCs led to changes of the gene expression pattern. A variety of pro-inflammatory cytokines and chemokines (CXCL10, CXCL11, CCL5), TLR3 and genes whose products function downstream of the TLR3 signalling pathway (e.g. IFN-alpha, IFN-beta) were significantly upregulated. Three mock transfected DC vs. three TB40 transfected DCs
transcription profiling by array
Michael Bonin <firstname.lastname@example.org>, Florian Gebhardt, Hermann Einsele, Juergen Loeffler, Markus Mezger, Tobias Kessler
Toll-like receptor 3 has no critical role during early immune response of human monocyte-derived dendritic cells after infection with the human cytomegalovirus strain TB40E. Mezger M, Bonin M, Kessler T, Gebhardt F, Einsele H, Loeffler J.