E-GEOD-14535 - mRNP-mRNA Association Map (Tier I - G10, HuR, Imp, PABP)
Submitted on 23 January 2009, released on 23 January 2009, last updated on 10 June 2011
In eukaryotic organisms gene regulatory networks require an additional level of coordination that links transcriptional and post-transcriptional processes. Messenger RNAs have traditionally been viewed as passive molecules in the pathway from transcription to translation. However, it is now clear that RNA-binding proteins play a major role in regulating multiple mRNAs in order to facilitate gene expression patterns. These tracks show the associated mRNAs that co-precipitated with the targeted RNA-binding proteins HuR, IMP-1 and PABP using RIP-Chip (Ribonomic) profiling Keywords: RIP-Chip For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf Replicates for IPs comparable IP-inputs performed independently in each of the ENCODE Tier 1 cell lines.