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E-GEOD-14398 - Expression patterns of sense-antisense transcripts in normal and cancer tissues

Status
Released on 1 March 2011
Organism
Homo sapiens
Samples (24)
Array (1)
Protocols (6)
Description
We characterized the expression patterns of sense-antisense transcripts, based on available cDNA sequences, in colon (colorectal) cancer tissues and in normal tissues surrounding the cancer tissues. Although expression balances (ratios) of most of sense and antisense transcript pairs did not change between patients or between normal and cancer tissues, we found 68 sense-antisense transcripts whose expression balances were altered specifically in colon cancer tissues. We conducted DNA microarray analyses by using the same set of probes designed for 2621 sense-antisense pairs to detect transcripts expressed in colon cancer tissues. These probes comprise 2358 pairs for the detection of protein-coding transcripts only, 250 pairs for the detection of protein-coding transcripts paired with non-protein-coding transcripts, and 13 pairs for the detection of non-protein-coding transcripts only.
Experiment type
transcription profiling by array 
Contacts
Rintaro Saito <rsaito@sfc.keio.ac.jp>, Akio Kanai, Chihiro Kohama, Hajime Nakaoka, Hidenori Kiyosawa, Hiroshi Yasue, Kazufumi Watanabe, Keisuke Kohno, Koji Numata, Kuniya Abe, Masaru Tomita, Naoyuki Yamamoto, Nobuhiro Ohkohchi, Soichiro Murata, Yuki Okada, Yuko Osada
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-14398.idf.txt
Sample and data relationshipE-GEOD-14398.sdrf.txt
Raw data (1)E-GEOD-14398.raw.1.zip
Processed data (1)E-GEOD-14398.processed.1.zip
Array designA-GEOD-8070.adf.txt
Links