Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-13227 - Transcription profiling of mouse thymus from AKR/J x FVB/NJ F1 versus DBA/2J x FVBF1 reveals 20-fold difference in mammary tumor metastatic capacity, due to differences in inherited polymorphisms
Submitted on 16 October 2008, released on 13 January 2009, last updated on 10 June 2011
F1 hybrids from (AKR/J x FVB/NJ) and (DBA/2J x FVB/NJ) outcrosses display a 20-fold difference in mammary tumor metastatic capacity, due to differences in inherited polymorphisms. Expression studies were performed to determine whether polymorphism-driven gene expression signatures predictive of outcome could be generated from normal tissues Experiment Overall Design: Thymus from adult F1 animals from (AKR/J x FVB/NJ) and (DBA/2J x FVB/NJ) outcrosses was collected and arrayed on Affymetrics chip to identify basal differences in gene expression between the different genotypes
transcription profiling by array, unknown experiment type