E-GEOD-10890 - Transcription profiling by array of human breast cancer cell lines after treatment with miR-221/222 mimics or inhibitors

Status
Released on 13 January 2009, last updated on 6 March 2012
Organism
Homo sapiens
Samples (112)
Array (1)
Protocols (3)
Description
mRNA breast cancer cell lines were profiled to study the function of hsa-mir-221 and hsa-mir-222. MCF7 cell lines were profiled after treatment with mir-221/222 mimics, and compared to profiles with transfection controls. Similarly, MDA-MB-231 cell lines were profiled after treatment with mir-221/222 inhibitors, and compared to profiles with transfection controls. Since ESR1 is a predicted target of mir-221/222 we also profiled MCF7 cell lines after disrupting ESR1 with an siRNA. Other breast cancer cell lines are provided because all cell lines were normalized together. Experiment Overall Design: mRNA breast cancer cell line profiles with some samples in duplicate or triplicate. See summary for more information.
Experiment types
transcription profiling by array, unknown experiment type
Contact
MIAME
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