E-CBIL-24 - Transcription profiling of liver from B6 and 129 mice fed on low and high fat diets
Released on 6 April 2007, last updated on 1 May 2014
Both environmental and genetic factors play important roles in the development of the metabolic syndrome. To elucidate how these factors interact under normal conditions, C57Bl/6 (B6) and 129S6/SvEvTac (129) mice were placed on a low-fat or high-fat diet. Liver samples were extracted and hybridized to Affymetrix Genome U74 (version 2) arrays.
transcription profiling by array, growth condition, strain or line
Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome. Biddinger Sudha B, Almind Katrine, Miyazaki Makoto, Kokkotou Efi, Ntambi James M, Kahn C Ronald.