E-BUGS-84 - Comparative genomic hybridization of S. aureus to examine Genetic Diversity in CC398 Methicillin-Resistant Staphylococcus aureus of Different Geographic Origin

Status
Released on 22 September 2009, last updated on 1 May 2014
Organism
Staphylococcus aureus
Samples (5)
Array (1)
Protocols (7)
Description
Abstract Staphylococcus aureus of sequence type 398 has emerged in Europe, North America and Asia and has typically been associated with livestock and their human contacts. We analysed two PVL-negative t034-ST398 isolates from humans in contact with pigs, and two t034-ST398 PVL-positive isolates from two unrelated adopted Chinese children using multi-strain microarrays to determine the genomic variability. The ST398 isolates clearly belong to the same lineage when compared to other clonal lineages. However, the four isolates cluster into two distinct groups corresponding to differences in epidemiology based on mobile genetic elements and resistance patterns, suggesting the two groups are epidemiologically distinct. Data is also available from http://bugs.sgul.ac.uk/E-BUGS-84
Experiment types
transcription profiling by array, ChIP-chip by array, reference, strain or line
Contact
Citation
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-BUGS-84.idf.txt
Sample and data relationshipE-BUGS-84.sdrf.txt
Raw data (1)E-BUGS-84.raw.1.zip
Processed data (1)E-BUGS-84.processed.1.zip
Experiment designE-BUGS-84.biosamples.png, E-BUGS-84.biosamples.svg
Array designA-BUGS-17.adf.txt
Links