Francesco Iorio

Francesco Iorio
Senior Bioinformatician - Open Targets

Francesco Iorio is the leading computational scientist in an Open Targets project that aims to identify new therapeutic targets and synthetic lethalities in cancer. He is responsible for analysing of data from a large-scale, genome-wide CRISPR-Cas9 knockout screen across hundreds of cancer cell lines, and concurrently leads the CELLector project to systematically evaluate the disease relevance of cancer cell-line models. Prior to joining Open Targets (a public-private initiative spearheaded by EMBL-EBI, GSK, Biogen and the Wellcome Trust Sanger Institute), Francesco was awarded a joint EMBL-EBI/Sanger Institute postdoctoral fellowship (ESPOD). This work focused on integrative computational frameworks for predicting and dissecting drug susceptibility in cancer based on the analysis of data from large-scale drug screens.

Francesco completed his PhD in the Systems, Synthetic and Computational Biology Laboratory of the TeleThon Institute of Genetics and Medicine (TIGEM, Naples, Italy), focusing on computational methods for drug discovery and repositioning based on the analysis of large compendia of gene expression profiles.</p>

ORCID iD: 0000-0001-7063-8913

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