Release 143 of ENA's assembled/annotated sequences is now available

Release 143 of ENA's assembled/annotated sequences is now available

16 Apr 2020 - 09:23

Release 143 of assembled/annotated sequences from ENA is now available on the EBI public ftp server at

It contains 263,421,789 sequence entries comprising 408,005,271,872 nucleotides.You can see the full release notes at:

ENA captures, preserves and presents the world's nucleotide sequence data. New content is included in ENA on a continuous basis and are distributed daily from our browser and RESTful service. The ENA assembled/annotated sequence release provides a quarterly snapshot of content in this important subset of ENA.

As previously announced, this is the last release in its current form. New data is already included in the ENA on a continuous basis and distributed daily from our browser, FTP and RESTful API services. The key change is that we will no longer make an additional separate quarterly release of the assembled/annotated subset of sequences. We will focus our resources on further developing and supporting our continuous distribution presentation products. 
We have created the following guide ( to assist users in moving away from the release. This guide outlines accessing assembled/annotated sequences, guidance on how to identify data based on a last updated timestamp and advice for establishing your own mirroring procedures using our portfolio of other access services. We will continue too further develop these services.
If you currently rely on any aspect of the separate assembled/annotated sequence release process for your work or resource, and cannot switch to one of our continuous distribution processes described in the above guide, please contact us. Please contact us with your questions or concerns at with the subject ‘ENA release retirement’.

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