Research highlights
Large-scale study enables new insights into rare eye disorders
A human interactome to prioritise drug discovery
BOSS-RUNS: streamlining dynamic nanopore sequencing
Spatial lung cell atlas offers insights into disease
Developmental cell atlas uncovers new cell states
New molecular microscopy uncovers how breast cancer spreads
AlphaFold applications – a community assessment
CNest: a new method for copy number variation analysis
New antibiotic resistance genes identified in tuberculosis
Shining a light on how bacteria interact
Uncharted territories in the human genome
Impact of DNA mutations on blood cell production uncovered
The MANE collaboration: working together to support genome science
New bacteria and viruses found on human skin
Characterising protein phosphosite function at scale
Genomic tracking of the COVID-19 pandemic in England
The Spatial Mouse Atlas: new insights into cell fate
The PROTACtable genome – a new route to drug discovery
Genomic surveillance of SARS-CoV-2 in England
Different immune responses identified in patients with COVID-19
Using metagenomic techniques to explore lichens
Repurposing drugs to manage COVID-19 progression
Linking genetics and age-related diseases
‘Patchwork’ tumours prevalent across multiple cancer types
Induced pluripotent stem cells reveal causes of disease
Adult blood cancers originate decades before diagnosis
The thousands of viruses living in your gut
Monitoring dangerous bacteria in freshwater
Darwin Tree of Life: looking back on 2020
Repurposing drugs for a pan-coronavirus treatment
Detailed map of human heart could guide personalised treatments
Achieving personalised therapeutics
Genome sequencing accelerates cancer detection
An organoid cell atlas to enhance biomedical research
New clues to a 500-year old mystery about the human heart
The curious genome of the tuatara, an ancient reptile in peril
Artificial intelligence finds patterns of mutations and survival in tumour images
Unparalleled inventory of the human gut ecosystem
Using drug screens and CRISPR to make better cancer drugs
Existing drugs can prevent SARS-CoV-2 from hijacking cells
Unpicking the complexity of DNA mutations
Distinguishing coronavirus genome mutations from inadvertent errors
DNA damage and faulty repair jointly cause mutations
New insights into the regulators that control cell shape
Adaptive evolution of mammalian immunity and metabolism
Cancer mutations occur decades before diagnosis
Chromothripsis in human cancer
Characterising RNA alterations in cancer
Pinpointing rare disease mutations
Using multiomics to define the mammalian primary germ layers
A machine learning approach to identify functional human phosphosites
B cells linked to immunotherapy for melanoma
Pinpointing the molecular mechanisms of ageing
Deciphering suitable cancer drug combinations
CRISPR offers new insights into critical cancer changes
Protein regulation mechanisms conserved for millions of years
Prioritising cancer drug targets using CRISPR
Monitoring antimicrobial resistance using sewage samples
Understanding early embryo development in mice
Almost 2000 unknown bacteria discovered in the human gut
More than 100 new gut bacteria discovered in human microbiome
Algorithm identifies multiple gene–environment relationships
Parasitic worm genomes reveal novel treatment possibilities
Gene activity shapes immunity across species
Classification of pre-clinical data could boost drug research
Genetics-based disease predictions for chronic blood cancers
Newly sequenced mouse genomes unearth unknown genes
New approach for testing cancer drug response
Roots of leukaemia detectable in blood years before diagnosis
Of mice and gorillas: how wild species may benefit from mouse genetic data
New insights into the origins of mutations in cancer
How did we domesticate sheep and goats?
The genetic risk factors for depression
Illuminating the ‘druggable genome’
Revealing the devil in early cell life detail
Study identifies new diabetes genes
How malaria parasites reproduce: new insights
Novel hearing loss genes identified
Bowel cancer study reveals impact of mutations on protein networks
The sexual dimorphism dilemma
Mouse genes could help decipher human disease
HipSci: The human stem cell bank of tomorrow
A race against the ageing clock
Ageing: cell coordination breakdown
Watching immune cells fight malaria
Genetic makeup of ‘room-mate’ influences health
Cancer genetics refine treatment decisions
Buffering mechanism protects embryonic development
What's an epigenome?
Drivers of evolution hidden in plain sight
‘Essential genes’ help focus research
![Puzzling out drug response [Graphic concept by Francesco Iorio, Illustration
by Spencer Phillips, EMBL-EBI]](https://acxngcvroo.cloudimg.io/v7/https://content.embl.org/sites/default/files/2021-10/Cancer_puzzle_EMBL-EBI_2016_credit_Spencer_Phillips_500x375.jpg?w=300&h=180)
Cancer cell lines predict drug response
Anatomy of a decision: mapping early development
Acute Myeloid Leukaemia is 11 diseases
Breast cancer study: towards personalised treatment
Foetus, or placenta?
Unpacking embryonic pluripotency
Allergy: the price of immunity?
![A snapshot of stem cell expression [IMAGE: EMBL-EBI/Spencer Phillips]](https://acxngcvroo.cloudimg.io/v7/https://content.embl.org/sites/default/files/2021-10/stem-cells_LABELS_EBI.jpg?w=300&h=180)
A snapshot of stem cell expression
Life is but a DREAM
Are protein domains indivisible?
Why is a dolphin not a cat?
"Hairclip" protein mechanism explained
Kidney cancer in Central Europe
BLUEPRINT: new perspectives on white blood cells
Gibbon genome joins its superfamily in Ensembl
Marmoset genome sheds light on chimeral twins
Sheep genome provides rich resource for agricultural research
Insights into genetics of cleft lip
How immune cells use steroids
Tsetse fly genome sequenced
Whole-genome dataset for bread wheat now available in Ensembl Plants
Functional genetic variation in humans: comprehensive map published
It's not just noise
Wired for change
Exploring survival
Where do turtles 'fit'?
How is a fish like a person?
