Public event/Ext Seminar event | Conference
About MASAMB
Bioinformatics and statistical genetics, twin themes of the long-running series of annual MASAMB meetings, have gained huge impetus from large-scale genome sequencing projects and development of high-throughput biological assay systems, including gene-expression, proteomic, metabolomic and single-cell genomics technologies. These immense data resources, and the underlying complexities of molecular and cell biology, provide exciting research opportunities for numerate scientists.
With typically around 80-120 participants from mathematics, statistics, computer science, bioinformatics, biology and related fields, the MASAMB meetings provide an intimate setting for exchanging ideas in methodological and applied research. Research students and scientists newly entering the field of genomic research are particularly welcome and encouraged to submit abstracts. Details of previous meetings are available at the MASAMB archive.
Thursday, 25 April, 2019
| 10:00 | Bus A leaving Cambridge (Station Rd by the corner of Tenison Rd) toward genome campus |
| 10:00 – 13:30 | Registration (EMBL-EBI South Building lower level) |
| 11:00 – 12:30 | Session 1: Systems Biology part 1 (all talks will be in the Kendrew Lecture Theatre, EMBL-EBI South Building lower level) |
| 12:30 – 13:30 | Buffet lunch and poster hanging |
| 13:30 – 15:00 | Session 2: Systems Biology part 2 |
| 15:00 – 15:30 | Coffee break |
| 15:30 – 16:50 | Session 3: Single-Cell RNA Sequencing |
| 16:50 – 17:05 | Flash talks |
| 17:05 – 19:30 | Poster and drinks session (Kendrew foyer, EMBL-EBI South Building lower level), and room check-in for on-site accommodation at Mulberry Court |
| 19:30 – 22:30 | Conference dinner (Hinxton Hall, chestnut suite) |
| 22:30 | Bus B leaving campus (from the Hinxton Hall stop) towards Cambridge (Station Rd by the corner of Tenison Rd) |
Friday, 26 April, 2019
| 8:00 | Bus B leaving Cambridge (Station Rd by the corner of Tenison Rd) toward genome campus |
| 8:30 – 9:00 | Sign in and coffee |
| 9:00 – 10:40 | Session 4: Population Genetics |
| 10:40 – 11:10 | Coffee break |
| 11:10 – 12:30 | Session 5: Selection |
| 12:30 – 13:30 | Buffet lunch |
| 13:30 – 14:50 | Session 6: Phylogenetics |
| 14:50 – 15:00 | Closing Remarks |
| 15:30 | Bus A leaving campus (from main entrance roundabout) towards Cambridge (Station Rd by the corner of Tenison Rd) |
Speakers are invited to prepare their slides in widescreen format (16:9) and email them to demaio@ebi.ac.uk before the 24th of April. For the 20 min talks, please allow time for questions (about 3-4 minutes) and change of speaker (about 1 min), so please aim for an approximately 15 min presentation. Posters have to be of size A1 or smaller.
Thursday, 25 April, 2019
| Session 1: Systems Biology part 1 | ||
| 11:00 – 11:20 | Felicity Allen | Deconstructing CRISPR/Cas9 knock-outs: frame shifts, cut rates and gene effects |
| 11:20 – 11:40 | Magdalena Strauss | Towards understanding molecular characteristics that predict gene essentiality in cancer cell lines |
| 11:40 – 12:00 | Anas Ahmad Rana | A Bayesian nonparametric integration approach for functional regulatory network inference in haematopoietic development from multi-omics data |
| 12:00 – 12:20 | Paula Avello Fernández | Heat the Clock: Entrainment and Compensation in Arabidopsis Circadian Rhythms |
| 12:20 – 12:25 Flash talk | Birgit Meldal | Yeast Complexome – The Complex Portal rising to the challenge |
| 12:25 – 12:30 Flash talk | Rahuman Sheriff | BioModels: a repository of curated mathematical models of biological and biomedical systems |
| Session 2: Systems Biology part 2 | ||
| 13:30 – 13:50 | Sarah Henze | Bayesian statistical inference based on MCMC facilitates the analysis of protease dynamics using tandem mass spectrometry measurements |
| 13:50 – 14:10 | Oliver Crook | Quantifying uncertainty in the spatial sub-cellular proteome |
| 14:10 – 14:30 | Sumon Ahmed | Uncovering gene-specific branching dynamics with a multiple output branched Gaussian Process (mBGP) |
| 14:30 – 14:50 | Grimur Hjorleifsson | Using microbial strain correspondence to improve genomic and metabolomic clusterings |
| 14:50 – 14:55 | Katharina Imkeller | Improving accuracy of phenotype detection in whole-genome CRISPR screens |
| 14:55 – 15:00 | Eldar Abdullaev | Modelling Segmental Duplications in the Human Genome |
| Session 3: Single-Cell RNA sequencing | ||
| 15:30 – 15:50 | Anna Cuomo | Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression |
| 15:50 – 16:10 | Yuanhua Huang | Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference |
| 16:10 – 16:30 | Felix Frauhammer | Machine learning based classification on a ground truth single-cell RNA sequencing dataset |
| 16:30 – 16:50 | Tobias Heinen | Modelling allelic imbalance in single-cell data |
| Flash talks | ||
| 16:50 – 16:55 | Tommi Mäklin | Bacterial genome assembly from multi-strain sequencing data |
| 16:55 – 17:00 | Nathan Beka | Optimizing parameters for a DNA library preparation model |
| 17:00 – 17:05 | Raquel Manzano Garcia | Bioinformatics pipeline for Personalised Breast Cancer Program |
Friday, 26 April, 2019
| Session 4: Population Genetics | ||
| 09:00 – 09:20 | Anna Hutchinson | Identifying Causal Genetic Variants – Not so credible Credible sets |
| 09:20 – 09:40 | Elena Vigorito | Mapping cis-eQTL from RNA-seq data with no genotypes |
| 09:40 – 10:00 | Daniel Seaton | Population genetics of in vitro neural differentiation |
| 10:00 – 10:20 | Asger Hobolth | Phase-type distributions in population genetics |
| 10:20 – 10:40 | Andreas Futschik | Efficient reconstruction of haplotypes using allele frequencies from a pool of individuals |
| Session 5: Selection | ||
| 11:10 – 11:30 | Michael Schimek | On the use of kNN-based methods to detect signatures of selection in whole genome scans |
| 11:30 – 11:50 | Carolina Barata | A Bayesian method to detect targets of selection in Evolve-and-Resequence experiments |
| 11:50 – 12:10 | Xinyu Yang | Identifying signatures of evolutionary dynamics across cancer types |
| 12:10 – 12:30 | Rui Borges | A polymorphism-aware phylogenetic model to measure signatures of allelic selection |
| Session 6: Phylogenetics | ||
| 13:30 – 13:50 | Julian Dosch | Measuring the similarity between complex feature architectures |
| 13:50 – 14:10 | Lars Jermiin | If it looks bad, it probably is… |
| 14:10 – 14:30 – CANCELLED | Lukasz Reszczynski | Characterisation of phylogenetic terraces and their impact on tree inference |
| 14:30 – 14:50 | Nicola De Maio | Fast and accurate statistical evolutionary alignment |
Co-organizing Institute: Cambridge Computational Biology Institute (CCBI).
Date: 25 - 26 Apr 2019
Time: 10:00 am - 3:00 pm
Timezone: Europe/London
Location: United Kingdom
Venue: European Bioinformatics Institute (EMBL-EBI) - Kendrew Lecture Theatre, GB
Deadline(s):
Closed