Dbfetch
ID KIR00139; SV 3; standard; DNA; HUM; 10880 BP. XX AC KIR00139; XX SV KIR00139.3 XX DT 29-APR-2005 (Rel. 1.2.0, Created, Version 1) DT 15-APR-2011 (Rel. 2.10.0, Sequence Updated, Version 3) DT 16-DEC-2021 (Rel. 2.11.0, Current Release, Version 3) XX DE KIR3DL3*005, Human Killer-cell Immunoglobulin-like Receptor XX KW Human Killer-cell Immunoglobulin-like Receptor; KIR3DL3*005; XX OS Homo Sapiens (human) OC Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; OC Catarrhini; Hominidae; Homo. XX CC -------------------------------------------------------------------------- CC IPD-KIR Release Version 2.11.0 CC -------------------------------------------------------------------------- CC Copyrighted by the IPD Database, Distributed under the Creative Commons CC Attribution-NoDerivs License, see; CC http://www.ebi.ac.uk/ipd/licence.html for further details. CC -------------------------------------------------------------------------- XX RN [1] RP 1-10880 RX PUBMED; 16634863. RA Steiner NK, Hurley CK; RT "KIR3DL3 allelic diversity: six new alleles exhibit both conservative and RT nonconservative substitutions"; RL Tissue Antigens 67:277-83(2006). XX RN [2] RP 1-10880 RX PUBMED; 17900289. RA Hou L, Chen M, Steiner NK, Belle I, Turino C, Ng J, Hurley CK; RT "Seventeen novel alleles add to the already extensive KIR3DL3 diversity"; RL Tissue Antigens 70:449-454(2007). XX CC -------------------------------------------------------------------------- CC The sequence below is the official allele sequence as approved by the CC KIR Nomenclature Committee. CC Any cross references may differ from the sequence shown below. CC -------------------------------------------------------------------------- XX DR EMBL; AY987939; AY987939.0. DR EMBL; EF492037; EF492037.0. DR EMBL; GU182342; GU182342.0. DR EMBL; HM999926; HM999926.0. XX FH Key Location/Qualifiers FH FT source 1..10880 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /db_xref="taxon:9606" FT /ethnic="Black" FT /cell_line="FH08" FT /cell_line="GM17143" FT /cell_line="GU1183" FT /cell_line="RDP9" FT CDS join(1..34,35..70,301..585,1859..2158,3741..4034,.., FT 10067..10119,10218..10343) FT /codon_start=1 FT /gene="KIR3DL3" FT /allele="KIR3DL3*005" FT /product="KIR3DL3 Killer-cell Immunoglobulin-like Receptor" FT /translation="MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHV FT TLQCRSRLGFNEFSLSKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPT FT GWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITED FT PLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYG FT KPSLSAQPDPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFP FT LGPVTHGGNYRCFGSFRALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIPFAILLF FT FLLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQ FT RPKTPPTDTSV" FT exon 1..34 FT /number="1" FT exon 35..70 FT /number="2" FT intron 71..300 FT /number="2" FT /partial FT exon 301..585 FT /number="3" FT intron 586..1858 FT /number="3" FT exon 1859..2158 FT /number="4" FT intron 2159..3740 FT /number="4" FT exon 3741..4034 FT /number="5" FT intron 4035..9604 FT /number="5/6" FT intron 9605..10066 FT /number="6" FT exon 10067..10119 FT /number="7" FT intron 10120..10217 FT /number="7" FT exon 10218..10343 FT /number="8" FT UTR 10344..10880 SQ Sequence 10880 BP; 2979 A; 2567 C; 2683 G; 2651 T; 0 other; atgtcgctca tggtcgtcag catggcgtgt gttgggttct tcttgctgga ggggccctgg 60 ccacatgtgg actgttaaaa tctagtaaga gtcgcttctt cagcacctgc tcaaagttct 120 cagctgacac ttgctgtagg gagacgccat gtctatgcgg gatgggtcct tcctgtagcc 180 ctgggcaccc aggtgtggta ggagccttag aaacatggaa atgggagaat cttctgagca 240 cagggaggga ggggcggctc cacatcctcc tctctaaggt ggtgcctcct tctcccccag 300 gtggtcagga caagcccttc ctctctgcct ggcccggcac tgtggtgtct gaaggacaac 360 atgtgactct tcagtgtcgc tctcgtcttg ggtttaatga attcagtctg tccaaagaag 420 acgggatgcc tgtccctgag ctctacaaca gaatattccg gaacagcttt ctcatgggcc 480 ctgtgacccc agcacatgca gggacctaca gatgttgcag ttcacaccca cactccccca 540 ctgggtggtc ggcacccagc aaccctgtgg tgatcatggt cacaggtcag aggctttctg 600 tctgggcttc tcactgtccc acctcctgaa tcccagagct tctggtgggg gcgtccatca 660 gggtccaatc atccaggccc cgactgtatt tggggtaaag ggggattcag tacagagaaa 720 tagttgctgt ggtgggaaga ataattgtcc ccagtgatgg ctacatggta atccatgaac 780 cctgtgacta tttatgttat agggcagggg actgaagagg aagatggagc tcaggttgtt 840 gatgagttga ccttgcgatg gggagacagc ctggactgtc ctgctgtgct cagagtaatc 900 acaagggtcc tcatgagagg aggaggaaga ggaaagtggg gttagagcaa cgtcgtggga 960 gggagactcc atcagccaca gcaggctttg aagatggggg aaggccatga gccacaaagg 1020 caggtggcct ctaagggctg gagaagtcaa gggaactgat tcttccctga gtctccagag 1080 gaaacacagc cctgcagatg ccttgatttt agcccagaga gaactgggtc cgatttctgt 1140 tctccagaag tggaaggggt cattgtattc tctcctgccc catgtttgtg acaattttct 1200 ccagcagcaa caggaaacca acacaggaac ccaggtgaag cacaggttaa gaaaccaaac 1260 aaggagaagt ttggctacac tgattttagc atgggtggga tactgatgct accaccaggc 1320 tcgatccaca tagggagggg ttgatgctcc tggaaccagc accaggggcc accctatgga 1380 agctggggcc atggagaaga cacagacatg aaaggagagg ctcccaatcc ccatcaggaa 1440 cagggacact gatgcctgcc ttactgatga gttcgtacct cctgccggcc tttccaatct 1500 gtccaaaaga gattgattca ggctgctaag agcctggaca tgcagcctgt catggttcct 1560 cttccacccc cacataaaca ccaggaaaga gattagtggg aaacagatac aacagcctaa 1620 gaggtgacac tgagcacagt gggaagggaa tcagggctac tagagacaga gagacaggga 1680 agagggaggg agacagatgg agggacctgc aacaggggtt atgggcacaa aggaacacgg 1740 agacacagac aggaaggaga gagatagaca ccatggaggg gaagcctcac ttatttcagg 1800 tcccatgaat gggatgagaa agggagacgc cttctgaact cacaacctct cttcttagga 1860 gtccacagaa aaccttccct cctggcccac ccaggtcccc tggtgaaatc aggagagacg 1920 gtcatcctgc aatgttggtc agatgtcagg tttgagcgct tccttctgca cagagagggg 1980 atcactgagg accccttgcg cctcgttgga cagctccacg atgcgggttc ccaggtcaac 2040 tattccatgg gtcccatgac acctgccctt gcagggacct acagatgctt tggttctgtc 2100 actcacttac cctatgagtt gtcggctccc agtgaccctc tggacatcgt ggtcgtaggt 2160 gagagaatac agacctgcct ctcacccttg ctgggagatg gagtgaatga tctaggactg 2220 gaagccccag gtggtcatga ggaagatgag tgtggggttc ctatggagag aaagtgactt 2280 ggtgaggtct gtaccaacaa aggcagagaa acaggagaca caagtacaga cctcatgtca 2340 taacatagaa gccagacaca ggggccatac aaggtgttag aaaaagagat aaagaggtaa 2400 agaagacaca gagagacaga catatcccag agagaggtgt ccttctatgc tgactttgtt 2460 cagagaccag gcacaggtta gaaggttcca ttctgtttta cctctacaaa gtgttctctc 2520 ccaggagaac ccaaagagac acatctatct ggcctgagtt gggccatgtg gccccaggct 2580 ggtggcacct acagatgttg tgtttattct taaacctctg ccttccgtgc agtggagctg 2640 tcatcgtccc aggacaccat ggccccaggt gagggagcag aacaccaacc cctgtatgct 2700 gtgagttcct ggagtcccca tactggattc tgaggctcat attcaaatag caccacatgt 2760 tataggatta ctgagaacaa aagcccacag agagacacgg agtgaaatca gggaaatcaa 2820 aaagcaaaga catgaacaca cacacagaat gagccagaag aagggaattg agagactcac 2880 agacacataa agagatagaa aaagagggca gagaagtgga gcgtatgatg gaaggaagca 2940 gagaaaagcc ctaaaatcag agccctgagg gaggggcaca aagacaggga aagataaaga 3000 tgtgaggatg gattgcagag actccaaaag ggaactagag agactgagag gcagagaaag 3060 acaaggagat ggagagagac agatgataga tggacagata gatatagata gatgaaagat 3120 aaaaggtaga tgatagataa tagagagaca ggtgatagac aaatagatga tgaatgactg 3180 atagatgata tagatagaca agtagaaaga cagacagatg atatataaat agatatagag 3240 agatagaaag acagataaac acatgatgat agatggatag atgcatacat acatacattg 3300 attgatagat gatagataac agagagatag gtcatagata cacagatgat gatagatgat 3360 agatacatac atagataaat gatagatcga tcaatagata gtagatagaa atatgcagaa 3420 agttatgagc aagacagaaa gtgagagact cagaattaaa gaaagaggaa gatcaagtca 3480 accagtccaa ggagggtcag agagaataaa atggtacaaa aaaagaaaac atagctaggg 3540 atggagaagt gaggtcagag acctagagag acagagaagg tggaaggagg aaatagacat 3600 gaagagagat gggggtggag ggtgagagag agaaagagag cattaagtca tagagcaggg 3660 gagtgagttc tcagctcagg tgtgaggaga gctgtgacaa ggaagaacct ccctgaggaa 3720 accacctctt ctccttccag gtctatatgg gaaaccttct ctctcagccc agccggaccc 3780 cacggttcag gcaggagaga atgtgacctt gtcctgcagc tctcggagct tgtttgacat 3840 ttaccatcta tccagggagg cagaggccgg tgaacttagg ctcactgcag tgctgagggt 3900 caatggaaca ttccaggcca acttccctct gggccctgtg acccacggag ggaactacag 3960 atgcttcggc tctttccgtg ccctgcccca cgcgtggtca gacccgagtg acccactgcc 4020 cgtttctgtc acaggtgaga aaacaccatg cctgtcccat gtcttgtgat cctagagcca 4080 tagctgagga gcttcctgct gatgatggag agaagcatgg acagatgccg agacagaaca 4140 cacagcatgg gtgtaagggc ggggtcaggg cgcaggatgg cagacagggc acctccaaac 4200 cctcctgtat ggcctgcaag gaggcccttg atcagggttc caggcaccca ggcagatgga 4260 gaaagaggtc agaacagacc cagaggaggg agactgggct ctgcctgggg agatcagagg 4320 ttctctcagc ccctcaacct tacccacttc ccagaagccc atcctggcct gtcacccaca 4380 gagagatgtc atcaccagca acgcctacac ccttttcttt ttgtttgaag aaatatttat 4440 tgaggtgaaa tatacctatg taatttacca cctttaccat ttttaagtgt gaagtctact 4500 gttcataaat acatttatag gctgggcacg gtggctcacg gttgtaatcc caacactttg 4560 agaggccaag gcaggtggat catttgagat caggggctca agaccaccct ggccaacatg 4620 gggaaaatcc atctgtacta aaaatacaaa ataataatta taatgataat aattagccga 4680 gcatggtggc acatgcctgt agtcccagct acttggtagg gttgggcagg agttgcactt 4740 aattgcagga ggcggaggtt gcagtgagct gagatcatgc cactgcactg cagcctgggc 4800 aacagagaga gacactctct caaaattaat taattaatta attagtattc tttttttttt 4860 accctccacc cttcccttcc tggcctctgg tagccaccat tctactctct acctttgtga 4920 gatccacctt ttagctcctg catatgagtg agaaatggaa atacttgtaa tgacctccag 4980 ttccattcat gtggctgtaa atgacaggat gttactcttt ctatggatga gttgtcccta 5040 ttgtgtgtgt gtaccacatt ctctccatcc attcacccac tgatgggcag gtaggttgat 5100 ccacatcttg gctactgtga acactgctgg aacagtcatg ggagtgcaga tgtcacttcg 5160 atacgctgat gtcctttcct ttgggtttac acccagtcat ggaattgcta gatcctctgg 5220 aagtgtcttt ttacattttg ttttatggtt tttgtttttg tttttgtttt ttttagacag 5280 tttcactctt gttgcccagg ctggagtgca gtggcgccat ctgggctcac tgcaacctcc 5340 acctccagga ttcaagagat tccccagcct cagcctccca agtagctggg ttactggctc 5400 ccaccaccac actcggctaa tttttatatt tttagtagag acagagtttc gctatattgg 5460 ccaggctgct cttcaactcc tgacctcaag tgacctaccc acctcggcct cccaatgtgc 5520 tgggattaca ggcatgaacc actgtgcccg acctcatttt attttttgag gaacttccat 5580 actcttctcc tctgtaatgg ctgtactaat ttacattcgt atcagcagtg taccagatgc 5640 aaccctggtt gactcagcag agcaagagac gtgcagtaag agagaattta gcttatttat 5700 gcacacgaca cttccactca ctcactcgtt cagccaatgc cccatgctct ggctgtgcag 5760 tgtggaatct tttcctattg ttgccataac aaatttccac aagcttcgtg gatgaaaacg 5820 tgtttttctt aattatctca cagtgctgta actcagaagt atgaactgca tttcactggg 5880 ctgatatcaa agggagagta aggctggatt tctttttaag gttccaagca agaatctgct 5940 ccttaacgtt tcccagctcc tagaggctcc cacgttcctg ggctcctggt ccccttcctc 6000 cttcctcctt cctcaaagcc cacaaaggct ggtcacgtct cacatggcat cattcagaat 6060 cttcttcttt acccacacct ttttctctga atcctgctct gccttcttcc tcatctttta 6120 aggactttgg gattctattg gggtcaccaa gataatccat ctcaatctcc ctaaaatcat 6180 ccagcgtacc ctctttttaa gttcagctga ttagcaaccg taatgccatc tgcaatcttc 6240 attcctcctt tcctgtaaaa taacatattc acaagctatg gaggctaaga cagggacatt 6300 ttgggggtgg ggcagcattc tcctgccttc cacaaatggt aaacaggatg catttggcct 6360 ctgctcttgg gacgctgata ttgcagatgg gtaaatgcga gggcagagaa tgaatgcaca 6420 agggtaccaa taaatgaatg atccattggg aagcatctgt gcaccaaatc tggggttttt 6480 tgtgtgtgtg tgtttttttt gttttctttt tttttttgag tagagtctct ctctgttcca 6540 caggctggag tgcagtagca caatctcagc tcattgcaac ctctgcctcc tgggttcatg 6600 caattctcct gcctcagcct accgagtagc tgggattaca gctgtgcgcc accacactcg 6660 gctaattttt ttggtatatt ttttagtaga aatgaggttt caccatgttg tgcaggctgt 6720 ctcaaactcc caatctcaag tgatcccacc gccttagcgt ccctaagtgc aaagattaca 6780 ggcgagagct actgcgccca gccaggattt aaaataagta atagataatg ctgagtatac 6840 aatttcaggt gacagagaag gtctcactga tcagataata tttgtgacct taatggaaaa 6900 aatggattca acccttggaa gattggcgga aggattttcc acactgagct ctcagccgtg 6960 aaggcacaaa ggtggaaaca ttcttagttc aaggaagagg ctctgcctca aatgctggga 7020 atgagatggg gagaatgaca agacgactgt ggagagacgg agagtacact gggtacacag 7080 gaaactaagg aggaacaagg agcgtgtgtt tgacactcac agcccttgga ttcaactcag 7140 agctaactag gaatccctac ctgattaaca gtgaccgaca tgaaaataag ggaggcccag 7200 gtgcgtaact ggaatctagg agaccgtgga aaaggcaatt cccgccccac tggtgaaacg 7260 tagggttgat ttacacacta aatgaatgaa agatggatat aagctatgct tgtgaggtag 7320 aatcatttgc agggagggct tgctgggttt gatttttcct agtagtttaa tccttgtttc 7380 attaatttct ttctgagatg tgtttttttt ctacatctaa atcaatacct ggcagaggag 7440 cgatagacac atgaggggtg gtgcaaatga agggacctag tataatataa tatacaagac 7500 tgtggatggg ggctcacacc tgtaacccaa cactttggga ggccaaggcg ggtagatcac 7560 ttaagggtag gagtttgaga ccagcctggc caacatggtg aaaccccgtc tgtactaaaa 7620 atacaaaaat tagcctggtg cattggcacc tgcctgtaat cccagcgact ggggaggctg 7680 aagcagaaga atggcttcaa ccctggaggc agaggttgaa ctgagatcgc atcactgcac 7740 tccagcctga cacaggggga ctctgtctca aaaaataaaa ataaaacata cataattatg 7800 acacacagaa attacaaagg caactggata ccaaccatca tttttctatt tctctgtgtt 7860 taattctttg accctttatc ttatccatta aacaatcagg ttaaacctct tccttatttg 7920 gctttctgtg agcttgggat catatggaaa atgtgaaagc ctcctgaacc caccagcaca 7980 ggtcctggaa tagagaacgt gctctgttca tggcataaaa cttgcccctt cacccaaatc 8040 ccccaattca tctctacttc caatcaccta tggagataca gatagatcat ggggaggtaa 8100 acactgatac tctttggagt gagctcagat cttggactca gagaccagtg ccagcactag 8160 cccctggtca catttcgtac taactcacag aaggacaggc tgtattgaaa caataaacga 8220 cggagagggc ggtccttccc cgtgcttctc gggtggaata gcagcctaat atatgtctca 8280 gcagatcaca aaaagtagca tgttgttcct gggctacatc attatttcat ggctgtttga 8340 tttaagtcag ttctacttca ctttttttat cttgatttca ttttttcttt cttttcttgg 8400 agaatgtaat ttttttgagt caagagggtt gtggtggtag aaactgtaaa gcacattcgc 8460 tgtgtatcaa tcccaatcca gtcttcccag agaagattct aaacacctcc tggaatgcac 8520 ctgggcctat accaattcct atcactcacc gtcactccag ggagacagaa cacacagaga 8580 acacattaca caggcaggtt cattactaac agataagcag cgagtgacaa cagaaaccta 8640 catttcaatg tgagccagtc cctcaaggct cagaaaagct gctcgagaca tgtggagtca 8700 ccccatatgc agtgtatctg ggggaaatca aaaagcagcc cagcctgggt tttgtaccct 8760 ggagccacag gaagcactca gctaaagcac tgcatgactt cctcctccag gaagaacagg 8820 aagacagccc aggctgttct gggatgttcc tcctgatctc aggacgttgc tgtcttagtc 8880 catttttgtt gctctaaagg aacacttgag cctgggtaac ttctaaagaa aagaaatgtg 8940 tttgcctcac agttctgcag gctgtactgg aagcatggca ccagcatcta tttcttgtga 9000 cggcctcagg ctgctcccac tctggcagaa gggaaggagg gtctgtctgt gcagagacca 9060 cagagatcac acggcaagag agggaccaag ggggaggggg agcgatggag cttccaagct 9120 cttttaacaa ccagttctcc aggaactaat agagggggaa cttgctaacc ccgtctcctt 9180 ggaacagcat tgatctgttc atgatggatc cacctccatg acccaaacaa ctcccaagag 9240 gcccaacctc ccaccctggg ggttacattt caatgtgagg tttgaagggg tcaaacatct 9300 aaactaaagc agttgtatcc tcagcacgtt ctatggttac tacaactgag aaagcaggag 9360 gaagctaggt ctcccgccat ctgggtgctt gtcctaaaga gacgttgtat gtggttacct 9420 gtcaatcaag aaatgtgaga caattcatat agaggaactg ctatgattag cttcttattg 9480 gtgtcttgtc ttcctccagg taactccaga cacctgcacg ttctgattgg gacctcagtg 9540 gtcatcatcc cctttgctat cctcctcttc tttctccttc atcgctggtg tgccaacaaa 9600 aagagtaact ctcacgaagc agaagccaga gagctcaggg ccatgtgggg aagcaggatg 9660 ggagcactca ggtgtgtgtt cctcacaggc aggatggtcc ctggcccaag gcaggagcca 9720 cagaggcagg actttctaga gagagcacca gactccctgc ctctgccttc agctcacaga 9780 ccattgcctg attctgaacc gtatcctcac atcccctgca gccactcaca tccaggagaa 9840 ggttccatga caggcagaaa gtgggacaca gaatcaatag gatgggaact cagagctata 9900 catgggatgg atccttgagc tcagagagat agaatgtctg agtctgctgt tggcaactga 9960 gggacctcag gcacctatgg cctccccctg tatgttggta tctgcttatg aaatgaggac 10020 ccagaagtgc cctccgagct gttttgacga cttccgtctt ctacagatgc tgttgtaatg 10080 gaccaagagc ctgcagggaa cagaacagtg aacagggagg taggtgctcc tccgcccagc 10140 ctcgtggcta gtcttattcc caaagagtcc tggaaaatgt gagcaccctc cctcactcag 10200 catttccctc cctccaggac tctgatgaac aagaccctca ggaggtgaca tacgcacagt 10260 tgaatcactg cgttttcaca cagagaaaaa tcactcgccc ttctcagagg cccaagacac 10320 ccccaacaga taccagcgtg taacacggaa cttccaaatg ctgagcgcag atccaaagtt 10380 gtcttctgtc cactagcacc acagtcaggc cttgatggga tcttctaggg agacaatagc 10440 cctgtctcaa aaccgggttg ccagctccca tgtaccagca gctggactct gaaggcgtga 10500 gtctgcatct tagggcatcg ctcttcctca caccacgaat ctgaacatgc ctctctcttg 10560 cttacaaatg tctaaggtcc ccactgcctg ctggagagaa aacacacttg cttagcccac 10620 aattctccat ttcacttgac ccctgcccac ctctccaacc taactggctt acttcctagt 10680 ctacttgagg ctgcgatcac actgaggaac tcacaattcc aaacatataa gaggctccct 10740 cttaacacgg cacttagata cgtgctattc cacctttcct cagagtatct ttcagccttc 10800 tgtcagcagt aaaacttata aatttttttt ataatttcaa tgtagttttc tattcttcaa 10860 gtaaacatgt ctgccctcat 10880 //