ID DQ009484; SV 1; linear; viral cRNA; STD; VRL; 14071 BP. XX AC DQ009484; XX DT 19-NOV-2005 (Rel. 85, Created) DT 16-DEC-2008 (Rel. 98, Last updated, Version 4) XX DE Avian metapneumovirus, complete genome. XX KW . XX OS Avian metapneumovirus OC Viruses; Riboviria; Negarnaviricota; Haploviricotina; Monjiviricetes; OC Mononegavirales; Pneumoviridae; Metapneumovirus. XX RN [1] RP 1-14071 RX PUBMED; 15666873. RA Bennett R.S., Nezworski J., Velayudhan B.T., Nagaraja K.V., Zeman D.H., RA Dyer N., Graham T., Lauer D.C., Njenga M.K., Halvorson D.A.; RT "Evidence of avian pneumovirus spread beyond Minnesota among wild and RT domestic birds in central North America"; RL Avian Dis. 48(4):902-908(2004). XX RN [2] RP 1-14071 RX DOI; 10.1128/JVI.79.23.14834-14842.2005. RX PUBMED; 16282483. RA Bennett R.S., LaRue R., Shaw D., Yu Q., Nagaraja K.V., Halvorson D.A., RA Njenga M.K.; RT "A wild goose metapneumovirus containing a large attachment glycoprotein is RT avirulent but immunoprotective in domestic turkeys"; RL J. Virol. 79(23):14834-14842(2005). XX RN [3] RP 1-14071 RA Bennett R.S., LaRue R., Shaw D., Yu Q., Nagaraja K.V., Halvorson D.A., RA Njenga M.K.; RT ; RL Submitted (15-APR-2005) to the INSDC. RL Veterinary and Biomedical Sciences, University of Minnesota, 1971 RL Commonwealth Ave, St. Paul, MN 55108, USA XX DR MD5; 4d730679bbc360413ad91e5b3709c657. DR EuropePMC; PMC1287544; 16282483. DR EuropePMC; PMC3941176; 24669221. DR EuropePMC; PMC4222263; 25060776. DR EuropePMC; PMC4821609; 27046055. XX CC Genome sequence lacks part of non-coding region. XX FH Key Location/Qualifiers FH FT source 1..14071 FT /organism="Avian metapneumovirus" FT /host="Canada goose" FT /isolate="15a" FT /mol_type="viral cRNA" FT /country="USA:Minnesota" FT /collection_date="2001" FT /db_xref="taxon:38525" FT CDS 14..1198 FT /codon_start=1 FT /product="nucleoprotein" FT /note="N" FT /db_xref="GOA:Q2Y2M6" FT /db_xref="InterPro:IPR004930" FT /db_xref="UniProtKB/Swiss-Prot:Q2Y2M6" FT /protein_id="AAY81654.1" FT /translation="MSLQGIQLSDLSYKHAILKESQYTIKRDVGTTPAVTPSSLQREVS FT LLCGEILYAKHTDYSHAAEVGMQYVSTTLGAERTQQILKNSGSEVQAVLTKTYSLGKGK FT NSKGEELQMLDIHGVEKSWVEEVDKEARKTMASATKDNSGPIPQNQRPSSPDAPIILLC FT IGALIFTKPASTIEVGLETAVRRANRVLNDALKRFPRIDIPKIARSFYDLFEQKVYYRS FT LFIEYGKALGSSSTGSKAESLFVNIFMQAYGAGQTMLRWGAIARSSNNIMLGHVSVQAE FT LKQVTEVYDLVREMGPESGLLHLRQSPKAGLLSLANCPNFASVVLGNASGLGILGMYRG FT RVPNTELFAAAESYARSLKESNKINFSSLGLTEEEKEAAENFLNINEEGQNDYE" FT CDS 1221..2105 FT /codon_start=1 FT /product="phosphoprotein" FT /note="P" FT /db_xref="GOA:Q2Y2M5" FT /db_xref="InterPro:IPR003487" FT /db_xref="UniProtKB/Swiss-Prot:Q2Y2M5" FT /protein_id="AAY81655.1" FT /translation="MSFPEGKDILLMGNEAAKAAEAFQRSLKKIGHRRTQSIVGDKIIT FT VSETVEKPTISKSTKVTTPPERRNAWGEKPDTTRNQTEEARNEATLEDTSRLYEEVFAP FT TSDGKTPAEEGMETPEKPKKKVTFKNDESGRYTKLEMEALELLSDNEDDDAESSVLTFE FT EKDTSALSLEARLESIDEKLSMILGLLRTLNVATAGPTAARDGIRDAMVGLREELIADI FT IKEAKGKAAEMMKEEAKQKSKIGNGSVGLTEKAKELNKIVEDESTSGESEEEEEEEDEE FT ESNPDDDLYSLTM" FT CDS 2131..2895 FT /codon_start=1 FT /product="matrix protein" FT /note="M" FT /db_xref="GOA:Q2Y2M4" FT /db_xref="InterPro:IPR005056" FT /db_xref="UniProtKB/Swiss-Prot:Q2Y2M4" FT /protein_id="AAY81656.1" FT /translation="MESYLVDTYQGVPYTAAVQTDLVEKDQLPARLTVWFPLFQTNTPP FT TVLLEQLKTLTITTLYTASQNGPILKVNASAQGAAMSALPKSFDVSASVALDDYSKLEF FT DKLTVCELKAVYLTTMKPYGMVSKFVNSAKAVGKKTHDLIALCDFLDLEKGVPVTIPAY FT IKSVSIKESESATVEAAIGGEADQAITQARIAPYAGLIMIMTMNNPKGIFKKLGAGVQV FT IVELGAYVQAESISRICRNWSHQGTRYVLKSR" FT CDS 3001..4614 FT /codon_start=1 FT /product="fusion protein" FT /note="F" FT /db_xref="GOA:Q2Y2M3" FT /db_xref="InterPro:IPR000776" FT /db_xref="UniProtKB/Swiss-Prot:Q2Y2M3" FT /protein_id="AAY81657.1" FT /translation="MSWKVVLLLVLLATPTGGLEESYLEESCSTVTRGYLSVLRTGWYT FT NVFTLEVGDVENLTCTDGPSLIRTELELTKNALEELKTVSADQLAKEARIMSPRKARFV FT LGAIALGVATAAAVTAGVAIAKTIRLEGEVAAIKGALRKTNEAVSTLGNGVRVLATAVN FT DLKDFISKKLTPAINKNKCDISDLKMAVSFGQYNRRFLNVVRQFSDNAGITPAISLDLM FT TDAELVRAVSNMPTSSGQINLMLENRAMVRRKGFGILIGVYGSSVVYMVQLPIFGVIDT FT PCWKVKAAPLCSGKDGSYACLLREDQGWYCQNAGSTVYYPNEEDCEVRSDHVFCDTAAG FT INVAKESEECNRNISTTKYPCKVSTGRHPISMVALSPLGALVACYDGVSCSIGSNKVGI FT IRPLGKGCSYISNQDADTVTIDNPVYQLSKVEGEQHTIKGKPVSSNFDPIEFPEDQFNI FT ALDQVFESVEKSKNLIDQSNKILDSTEKGNAGFVMVIVLIVLLMLAAVGVGIFFVVKKR FT KAAPKFPMEMNGVNNKGFIP" FT CDS 4648..5202 FT /codon_start=1 FT /product="matrix protein 2-1" FT /note="M2" FT /db_xref="GOA:Q2Y2M2" FT /db_xref="InterPro:IPR000571" FT /db_xref="InterPro:IPR009452" FT /db_xref="InterPro:IPR036855" FT /db_xref="UniProtKB/Swiss-Prot:Q2Y2M2" FT /protein_id="AAY81658.1" FT /translation="MSRKAPCKYEVRGKCNRGSECKFNHNYWSWPDRYLLLRSNYLLNQ FT LLRNTDRSDGLSLISGAGRDDRTQDFVLGSTNVVQNYIDNNENITKASACYSLYNIIKQ FT LQETDVRQARDNKVDDSKHVALHNLVLSYMEMSKTPASLINNLKKPPKEKLKKLAKLII FT ELSAGVENDSTAAMQDSANSD" FT CDS 5159..5374 FT /codon_start=1 FT /product="matrix protein 2-2" FT /note="M2" FT /db_xref="UniProtKB/Swiss-Prot:Q2Y2M1" FT /protein_id="AAY81659.1" FT /translation="MTLQLPCKIVQTLIKCGEHGLIFLKMKLDDMVWTKNELVDIISTE FT IVKVHANIFKCRLEDIEIIYVNTFLS" FT CDS 5398..5925 FT /codon_start=1 FT /product="small hydrophobic protein" FT /note="SH" FT /db_xref="GOA:Q2Y2M0" FT /db_xref="UniProtKB/Swiss-Prot:Q2Y2M0" FT /protein_id="AAY81660.1" FT /translation="MEPLKVSGSGGIPMKTRLNIILEKSINKILIILGLLLIASTVITI FT TLTVEYIRVENELQLCKMGAEVAKTTLEPPAQPTKTTPTLTSTRSTTATFKTRPVSRTN FT HHTNPSCWREEEKCQNITAKWSNCFGTFLPVRVNCTVLRELCDEQLGNHTTVQVSKRCT FT CIYALNWDCSYA" FT CDS 6111..7868 FT /codon_start=1 FT /product="attachment glycoprotein" FT /note="G" FT /db_xref="GOA:Q2Y2L9" FT /db_xref="UniProtKB/Swiss-Prot:Q2Y2L9" FT /protein_id="AAY81661.1" FT /translation="MEVKVENVGKSQELKVKVKNFIKRSDCKKKLFALILGLVSFELTM FT NIMLSVMYVESNEALSLCRIQGTPAPRDNKTNTENTKKETTFHTTTTTRDPEVRETKTT FT KPKTNEGATSPSRNLTTKGDIHQTTRATTEAELEKQSKQTIEPDTSTKKHTPTRPSSES FT PTTTQATAQLTTPTAPKASIAPKNRQATTKKTETGTTTTSRAKKTNNPTETATTTLKAT FT TETGKGKEGPTQHTIKEQPETTAGETTTPQSRRTTSRPAPTTKTEEEAETTKTRTTKST FT QTSTGPPGPTRSTPSKTATENNKRTTTIKRPNTANTDSRQQTRTTAEQDRQIQTKAKPT FT TNGAHAQTTTTPEHNTDTTNSTKESSKEDKTTRDPSSKTPTDQEDASKGTTAANPRKNT FT EANTRTPPTTTPTRHTTESATSTTGDKTKAKTTRWKSTADRQPIRNSTTAETKTAQSKQ FT PTPKQLSNNTTPENTTPPNNKSSSQTDAAPTEEIEIRSSLWRRRYVYGPCRENVLEHPM FT NPCFKDNTTWIYSDNGRNLPAGYYDSKTDKIICYGIYRGNSYCYGRIECTCKNGTGLLS FT YCCNSYNWS" FT CDS 7913..13492 FT /codon_start=1 FT /product="RNA polymerase" FT /note="possible frameshift" FT /db_xref="GOA:Q2Y2L8" FT /db_xref="InterPro:IPR014023" FT /db_xref="InterPro:IPR025786" FT /db_xref="InterPro:IPR026890" FT /db_xref="InterPro:IPR039736" FT /db_xref="UniProtKB/Swiss-Prot:Q2Y2L8" FT /protein_id="AAY82583.1" FT /translation="MDPLNEGVVNVYLTDSYLKGVISFSETNAIGSCLLGKHYLKKDNT FT SKVAIESPVVEHIRLRNAFQTRIKEKNLRVVEPVNMQSEVMRNSYTCELNLLKQLITRS FT KDISSLKLDMICDWLQLKSTSENPSVLKFVDVRCIPDWVSTWFSSWYNLNKLILEFRRE FT EVACTGSIICKTIGSIMFIISSFGCVIKSNKSKRISFMTYNQVLTWKDVMLSRFNANLC FT VWISNSLNKNQEGLGLRSNLQGALVNKLYEIVDSMLSVCSNEGFTLVKEFEGFIMSEIL FT KITEHAQFSTRFRNTLLNGLVDQLAKMRGLNRKRVSGTVLEGNQYPMYETTLATLGGAL FT KTIRLLVNKNLDNAAELYYIFRIFGHPMVEEREAMDAVRLNNEITKILKLESLTELRGA FT FILRIIKGFVDTNKRWPKIKNLKVLSRRWIMYFKAKSYPSQLELSSQDFLELAGVQFEQ FT EFAIPERTNLEMVLNDKAISPPKNLIWSVFPKNYLPTNIRERFTEEMFNSSEKLKTRRV FT LEYYLKDNKFDQNDLKKYVVRQEYLGDKEHVVSLTGKERELSVGRMFAMQPGKQRQVQI FT LAEKLLADNIVPFFPETLTKYGDLELQRIMEIKSELSSVKSRRNDSYNNYIARASIVTD FT LSKFNQAFRYETSSVCADVVDELHGTQSLFCWLHLTVPLTTMICTYRHAPPETEGVYDI FT DKIKEQSGLYRFHMGGIEGWCQKLWTMEAVSLLDVVSVKNRVQLTSLLNGDNQSIDVSK FT PVRLSQGVDEVKADYSLAVKMLKEIRNAYKDIGHKLKEGETYISRDLQFMSKVIQSEGV FT MHPSPIKKILRVGPWINTILDDIKTSAESIGSLCQELEFRGESLLVSLILRNFWLYELW FT MHESKSHPLAGKQLYRQLSKTLAITQKFFGITKETDVVNLWMNVPMQFGGGDPVVLYRS FT FYRRTPDFLTEAVSHMSVLLKVYGKAKEGSKKDFFKALLSVDKNKRATLTTLMRDPQAV FT GSERQARVTSEINRAAVTSVLSLSPNQLFCDSAIHYSRNEEEVGLIAQNITPVYPHGLR FT VLYESLPFHKAEKVVNMISGTKSITNLLQRTSAINGEDIDRAVSMMLENLGLLSRILSV FT CQDDITLPTKANGDLICCQVSRTLRERSWDNMEIVGVTSPSIVTCMNIVYSSSSQLKGI FT TIEKFSTDKTTRGQRGPKSPWVGSSTQEKKLVPVYNRQILSKQQKEQLEAIGKLRWVYK FT GTQGLRRLLDKICIGSLGISYKNVKPLLPRFMSVNFLHRLSVSSRPMEFPASVPAYRTT FT NYHFDTSPVNQTLSERFGNEDINLVFQNAISCGISVMSVVEQLTGRSPKQLVMIPQLEE FT IDIMPPPVFLGKFDYKLVEKISSDQHIFSPDKLDLVTLGKMLMPSTSGAKSDQFWNRKE FT NFFHGNNLVESLSAALACHWCGILTEQCNENNIFRREWGDGFVTDHAFIDFKTFVGVFK FT TKLLCGWGSRGGDIKDRDMIDESIDKLIRVDNSFWRMFSKVILEPKVRKRVMLFDVKIL FT SLVGYAGFKNWFIDHLRSSDLCEVPWVVNADSEIVEVSAVKIYLQLLRVSSPLRITVLN FT YSDMAHAITRLIRRKSMHDNVPSISRTLSPAELAPVVEPTVQMNLFPKITFERLKNYET FT VSGSTRGKLTRNYMVMLPWQHINRFNFVFSSTGCKISVKACIGRLIQDLNPTVFYFVGE FT GAGNWMARTACEYPNAKFVYRSLKDDLDHHFPLEFQRVLGNMNRVIDGGEGLSMDTTDA FT TQKTHWDLIHRICKDALLITLCDAEFKDRDDFFKMVTLWRKHVLSCRICTTYGTDLYLF FT AKYHAKEQSIKLPYFVRSIATYVMQGSKLSWIRVLCPSNTWPPQ" XX SQ Sequence 14071 BP; 4997 A; 2605 C; 3214 G; 3255 T; 0 other; gggacaagtg aaaatgtctc ttcaggggat tcagcttagt gatttgtcct ataagcatgc 60 aatccttaaa gaatcacagt acacaatcaa aagagatgtg gggacaaccc cagctgtcac 120 tccatcttct ctgcagaggg aagtatcact cttatgtgga gagatactgt atgccaagca 180 cacagattac tcacatgcag ctgaagtagg aatgcagtat gtgagcacca cactgggagc 240 agaacgtaca caacagatac taaagaactc aggtagtgag gtgcaggcag tattgaccaa 300 gacatactct cttgggaagg gcaaaaacag caaaggggag gagttgcaaa tgttagacat 360 acatggggtt gaaaaaagtt gggttgaaga agttgacaag gaggcaagga aaaccatggc 420 ctcagctaca aaggacaact caggaccgat accacaaaat caaagaccat catccccgga 480 tgctcctatc atactactct gcataggagc attaatcttc acgaagccgg catcaacaat 540 cgaagttggg ctggagacag ctgttagaag ggcaaaccgc gtgctgaatg atgcattgaa 600 aaggttccca aggatcgaca tccccaaaat tgcgaggtcc ttttatgatc tgtttgagca 660 gaaagtttac tataggagct tgtttataga gtatggcaaa gcccttgggt cttcttccac 720 aggaagcaag gcagaaagcc tgtttgtgaa cattttcatg caagcttatg gtgcaggtca 780 gacaatgcta aggtgggggg caattgccag atcatccaac aatataatgt tgggccatgt 840 ctccgtacaa gcggaactca aacaggtcac ggaggtatat gatctagtca gagagatggg 900 ccctgagtca ggtcttctcc acctgaggca aagccctaag gctggattgt tgtcacttgc 960 taattgtcca aattttgcaa gtgtggtgct aggaaatgcc tcaggattgg ggatacttgg 1020 tatgtacaga ggaagagtac caaacacaga gctatttgct gcagcagaaa gctatgcaag 1080 aagcctaaaa gaaagcaata agataaattt ctcatctctt ggtctgacag aagaggaaaa 1140 agaagctgcc gagaactttc tcaacataaa tgaggaaggc cagaatgatt atgagtaatt 1200 aaaaaacggg acaagtcaaa atgtcctttc ctgaggggaa agatatattg cttatgggca 1260 atgaagctgc aaaagcagca gaagcttttc aaagatcact aaagaaaata ggacatagaa 1320 gaacacagtc aattgttggg gacaaaataa tcacagtgtc cgaaactgta gaaaagccaa 1380 ccataagtaa gtcaacaaag gtcaccacac cccctgaaag aagaaatgca tggggcgaaa 1440 aaccagatac cacaagaaac caaacagaag aagccagaaa cgaggccaca ctggaggata 1500 caagccggtt gtacgaggag gtctttgctc ctacgagtga tggcaagact ccagccgagg 1560 aaggaatgga aacacctgaa aaaccaaaaa agaaagtgac attcaagaat gatgaatcag 1620 gaagatacac aaaacttgag atggaagcac tagaattatt atcagacaat gaggatgacg 1680 atgcagaatc atctgtgttg acttttgaag aaaaagacac ctctgctctt agtcttgaag 1740 ccaggctgga atctattgac gagaaattga gcatgatact agggttgctg agaacactca 1800 atgttgccac ggctgggccc accgcagcta gagacggcat ccgggacgca atggtagggt 1860 tgagagaaga attaattgct gacatcatca aagaagcaaa aggaaaggca gccgagatga 1920 tgaaagaaga agcaaagcag aagtcaaaaa tagggaatgg gagcgtaggc ctaactgaga 1980 aggctaagga actgaacaag atagtggagg atgagagcac aagtggtgaa tcagaggaag 2040 aagaagagga agaagacgaa gaagagagca acccagatga tgacctatac tcccttacta 2100 tgtagttaat aaaaaacggg acaagtggaa atggagtcct atcttgtaga cacctaccaa 2160 ggtgtccctt atactgctgc tgtacaaact gatttggtgg agaaagacca actgcctgca 2220 aggttaacag tatggttccc tctattccaa accaacacac ctcctacagt gctactagag 2280 cagcttaaga ctctaacaat tacaactttg tacacagcct ctcagaatgg cccaatactg 2340 aaggtcaatg catcagcaca aggggctgca atgtcagcat tgccaaaaag ctttgatgtt 2400 agtgcatcag tagcactaga tgactacagc aaactagagt ttgacaaact gacagtgtgt 2460 gagttaaaag cagtctattt gacaacaatg aaaccttatg gtatggtctc aaagtttgtc 2520 aactcggcca aagcagttgg aaagaaaaca cacgatttga ttgctctctg tgacttcctt 2580 gacctagaga agggagttcc agtgactata ccagcctata taaagtctgt gtcaataaaa 2640 gagagtgaat cagcaactgt tgaagctgca attggtgggg aggcagatca agctataact 2700 caagctagga ttgctccata cgctggcttg atcatgataa tgacaatgaa caaccctaag 2760 gggatcttca aaaaactggg tgcaggagtt caggtaatag tggagttagg agcatatgtt 2820 caagcagaaa gcataagcag aatctgcagg aactggagcc accagggtac gagatatgtc 2880 ctgaagtcaa gatgaacaca gagagtacac ctaccaaatc acagcagcaa tttcgttttt 2940 aaccaactca tagttaatac ctagcttgat attatttaga aaaaattggg acaagtgaaa 3000 atgtcttgga aagtggtact gctattggta ttgctagcta ccccaacagg ggggctagaa 3060 gaaagttatc tagaggaatc atgcagtact gttactaggg gatacctgag tgttttgagg 3120 acaggatggt atacaaatgt gttcacgctt gaggttggag atgtggaaaa tctcacatgt 3180 accgacgggc ccagcttaat aagaacagaa cttgaactga caaaaaatgc acttgaggaa 3240 ctcaagacag tatcagcaga tcaattggca aaggaagcta ggataatgtc accaagaaaa 3300 gcccggtttg ttctgggtgc catagcatta ggtgtggcaa ctgctgctgc agtgacggct 3360 ggtgtagcga tagccaagac aattaggcta gaaggagaag tggctgcaat caagggtgct 3420 ctcaggaaaa caaatgaggc tgtatctaca ttaggaaatg gtgtgagggt actggcaaca 3480 gctgtgaatg atctcaagga ctttataagt aaaaaattga cgcctgcaat aaacaagaac 3540 aagtgtgaca tctcagacct taagatggca gtgagctttg gacaatacaa tcggaggttc 3600 ctcaatgtgg taagacagtt ctctgacaac gcgggtatta cgcctgcaat atcactagat 3660 ttaatgactg atgctgagct tgtaagagct gtaagcaaca tgcccacgtc ttcaggacag 3720 atcaatctga tgcttgagaa tcgggcaatg gtcagaagga aaggatttgg gattttgatt 3780 ggagtttatg gtagctctgt ggtctatatg gtgcagcttc ctattttcgg tgtgatagac 3840 acaccatgtt ggaaggtgaa ggctgcacca ttatgttcag ggaaagacgg gagttatgca 3900 tgtctcttgc gagaagacca aggttggtat tgtcaaaatg ctggatccac agtttattat 3960 ccaaatgagg aggactgtga agtaagaagt gatcatgtgt tttgtgacac agcagctggg 4020 ataaatgtag caaaggagtc agaagagtgc aacaggaata tctcaacaac aaagtacccc 4080 tgcaaggtaa gtacagggcg tcacccaata agcatggtgg ccttatcacc actgggtgct 4140 ttggtagcct gttatgacgg tgtgagttgt tccattggga gcaacaaggt tggaataatc 4200 agacctttgg ggaaagggtg ttcatacatc agcaatcaag atgctgacac tgttacaatt 4260 gacaacccag tataccaatt gagcaaagtt gaaggagaac aacacacaat taaagggaag 4320 ccagtatcta gcaattttga cccaatagag tttcctgaag atcagttcaa catagcactg 4380 gatcaggtgt ttgaaagtgt tgagaagagc aagaatctga tagaccagtc aaacaagata 4440 ttggatagca ctgaaaaggg gaatgcagga tttgtcatgg tgatagtcct cattgtcctg 4500 ctcatgctgg ctgcagttgg tgtaggtatc ttctttgtgg ttaagaagag aaaagctgct 4560 cccaaattcc caatggaaat gaatggtgtg aacaacaaag gatttatccc ttaattttag 4620 ttactaaaaa attgggacaa gtccaagatg tctcgcaagg ctccctgcaa atatgaagta 4680 cggggcaagt gcaatagagg cagtgaatgc aagtttaacc ataattactg gagttggcca 4740 gacaggtacc tgttactaag gtccaattac ctgctgaatc aattactgag aaatacagat 4800 agatcagatg gtctgtcatt aatctcagga gcagggcgag atgataggac acaagatttt 4860 gttttggggt caacaaatgt ggtccagaat tacattgaca acaatgagaa tataacaaaa 4920 gcgtcagctt gttacagtct gtataatatc ataaaacaac tgcaagagac tgacgtaagg 4980 caggccagag acaacaaagt tgatgacagc aaacatgttg ctctacataa tttagtgtta 5040 tcatatatgg aaatgagcaa aacccctgca tccttgataa acaacttgaa gaagcctccc 5100 aaggaaaaac taaaaaaatt ggcaaagctg atcattgaat tgtcagcagg agtggaaaat 5160 gactctacag ctgccatgca agatagtgca aactctgatt aaatgcggag aacatggcct 5220 gatctttctg aagatgaaat tagatgatat ggtatggacc aaaaatgaat tggtagacat 5280 aatttccact gaaatagtta aagtgcatgc taatatattc aaatgtaggc tagaggatat 5340 agaaatcatt tatgttaata catttctaag ttaataaaaa aattgggaca agtcaacatg 5400 gagcccctga aagtctctgg aagtggaggg ataccgatga agacaaggct taatatcata 5460 cttgagaagt caatcaataa aatcttgatc attttaggat tattattaat tgcctcaact 5520 gtaattacaa tcacactcac agtggagtat ataagagtag aaaatgaatt gcaactttgc 5580 aagatgggag cagaagtggc caagacaact ctggaaccac cagcacagcc aacgaagaca 5640 actcctacac taaccagcac caggtcaacc accgcaacct tcaaaaccag accagtttca 5700 aggaccaatc atcacactaa tcccagctgc tggagagagg aggaaaagtg ccagaacatc 5760 acagctaaat ggtccaattg ttttggcaca tttctacctg tgagggtgaa ctgcacggta 5820 ttaagagaat tgtgtgatga gcagctaggc aatcacacaa cagttcaagt atcaaagagg 5880 tgtacatgca tatatgcatt aaattgggat tgtagttatg cttgagagag aaactacact 5940 agcagactcc aatgaggtcc gcaaaagatt aaaaaaacat aaaccaattt tttagttatt 6000 taaaaatcat gagtatgtct ggacagtgcc aaggctagga aaaactaaca cgggaacagg 6060 taatccaatg attacaaatg atcagagaag gaaaaacggg acaagtcaac atggaggtca 6120 aggtagagaa tgttggcaag tcacaggagc ttaaagttaa agtcaagaat tttataaaaa 6180 ggtctgattg caagaaaaaa ctttttgcct tgattttagg gctagtcagc tttgaactca 6240 ctatgaatat aatgctgtct gtcatgtatg tggagtcaaa tgaggccctg agtttatgta 6300 ggatccaagg gactcccgct ccaagggaca ataagacaaa cacagaaaac acaaaaaagg 6360 aaacaacatt ccacacaacg accacaacaa gggatccaga ggtgagggaa acaaaaacca 6420 ccaagcccaa gaccaatgaa ggagcaacaa gcccaagcag gaacctcacc accaagggag 6480 acatacacca aacgacaaga gcaacaacag aggcagaact ggaaaaacaa agcaagcaaa 6540 ccatagagcc agacactagc accaaaaagc acactcccac aaggccaagc agcgaatccc 6600 ccaccacaac acaagcaact gcacaactga caacaccaac agccccaaaa gcaagcatag 6660 cacccaagaa cagacaggca acaaccaaaa aaaccgaaac gggcaccaca acaacaagca 6720 gagcaaagaa aaccaacaac ccaacagaga cagcaacaac aactctcaaa gcaacaacag 6780 aaacaggcaa gggcaaagag gggccaacac agcacacaat caaagaacag cccgaaacaa 6840 cagcaggaga aacaactacc ccacagtcaa gaagaacaac cagcaggcca gccccaacaa 6900 caaaaaccga agaggaggca gaaaccacca aaacaagaac aaccaaaagc acccaaacaa 6960 gcacaggccc accaggacca acaagaagca cacccagcaa aacagcgaca gaaaacaaca 7020 agagaaccac aacaataaag agaccaaata cagcgaacac agacagcaga caacagacca 7080 gaacaactgc agagcaagac cgacagattc aaaccaaggc caaacccacc acaaatgggg 7140 cccatgcgca aaccaccacc accccagagc acaacacaga cacaacaaac agcacaaagg 7200 aaagttccaa ggaggacaaa acaaccagag accccagcag caaaacacca accgatcaag 7260 aggatgccag caaagggaca accgcagcca atcccagaaa aaacaccgag gcaaacacga 7320 gaacaccccc aacaactacc ccgacaaggc acaccacaga atcggccaca agcacaacag 7380 gggacaaaac caaagcaaaa accacaagat ggaaaagcac agcagacaga caacccataa 7440 ggaacagcac aacagcagaa accaagacag cccagagcaa acaacccaca ccgaaacagc 7500 tgagcaacaa cacaacacca gagaacacta caccaccgaa caacaaaagc agcagccaaa 7560 cagacgccgc accaacagaa gaaatagaaa tcagatcaag cctctggcga aggagatatg 7620 tttatgggcc ctgcagagag aatgttctgg aacatccgat gaatccatgt tttaaggaca 7680 acactacatg gatttattcg gacaatggaa ggaatttgcc agctggttat tatgatagta 7740 aaacagataa aataatttgc tatggaattt atagaggtaa ctcatattgt tatgggcgaa 7800 tagagtgcac atgtaaaaat ggaacaggac tactatccta ctgctgcaac tcgtacaact 7860 ggagttagtt taagagcaag ttagttaatt aaaaagaagg accaagttaa aaatggatcc 7920 actaaatgaa ggggttgtga atgtgtacct aactgattct tatttaaagg gtgtaatatc 7980 ttttagtgaa accaatgcaa taggatcttg ccttctaggt aaacactacc ttaaaaaaga 8040 taacacttcg aaagtggcca tagagagccc tgttgtagaa cacatcagat taagaaatgc 8100 tttccagact aggatcaagg agaaaaacct aagggtagtg gaacccgtca acatgcaaag 8160 tgaagtcatg agaaattctt acacctgtga attgaatcta ctcaaacaac tcataacgag 8220 aagtaaagac ataagctcac tcaaacttga catgatatgt gactggttgc aattaaaatc 8280 gacatccgaa aatccatctg tcctaaagtt tgtggatgtg aggtgtattc ctgactgggt 8340 gagcacttgg ttcagcagct ggtacaattt aaacaagctt atattagagt ttagacgtga 8400 agaagtagcc tgcacagggt ctattatttg taaaacaata gggagcataa tgtttatcat 8460 ttcatcattt gggtgtgtta tcaaaagcaa caagagcaaa agaatcagct ttatgacata 8520 caatcaggtg ctgacatgga aggatgtcat gttaagcagg ttcaatgcaa atctatgtgt 8580 gtggatcagt aacagtctta acaaaaatca agaagggtta ggtcttagaa gcaatttaca 8640 aggggccctg gttaacaaat tatatgagat tgttgactct atgctcagtg tttgcagcaa 8700 tgaggggttc acccttgtta aagaatttga agggttcata atgagtgaga ttctgaaaat 8760 aacagagcat gctcagttta gcacaaggtt cagaaacact ttgttgaatg ggttagtaga 8820 ccaactggca aagatgaggg gtctaaacag gaaaagggtt tcaggcactg tcttagaagg 8880 aaaccagtat ccaatgtatg agacaacatt agccacacta gggggagctt taaaaacaat 8940 aagactcctg gtaaacaaga acttagacaa tgccgctgag ctgtactaca tttttaggat 9000 ttttggccac ccaatggttg aagagagaga agctatggat gcagtcagac ttaataatga 9060 gatcacaaaa attctgaaat tagagagtct tacagagttg agaggagcct tcattttaag 9120 gatcataaaa ggctttgttg acacaaacaa gagatggcct aaaatcaaga atctcaaagt 9180 gttaagcaga aggtggatta tgtactttaa agctaagagt tatccaagcc agttggaatt 9240 aagtagtcaa gatttccttg aattagcagg agtgcagttt gagcaggaat ttgcaatacc 9300 agagagaaca aatcttgaga tggtcttgaa tgataaggcc atctcaccac ccaaaaattt 9360 aatatggtca gtattcccta aaaattatct tccaacaaac atcagagaga gattcactga 9420 agaaatgttc aactcaagtg agaaattgaa gacaagaagg gtgttggagt attacttaaa 9480 agacaacaag tttgatcaga atgacctgaa aaaatatgtt gttaggcaag agtacttagg 9540 tgataaggaa catgtagtgt cattaacagg gaaagaacgt gagttaagtg tgggaaggat 9600 gtttgcgatg caaccaggaa aacaaaggca agttcagatc ttagcagaaa agctacttgc 9660 agacaatata gtaccattct tccctgagac attgacaaaa tatggtgatt tagaactaca 9720 aaggattatg gaaataaaat ctgagttgtc atcagtaaag tcacggagaa atgacagtta 9780 caacaattat attgccagag catcaatagt gactgatctt agtaagttta accaggcttt 9840 tcggtatgag acatcttctg tctgtgcaga tgtagttgat gaattgcatg gcacacaaag 9900 tctcttttgc tggctgcatt tgactgtgcc actaactact atgatttgca catataggca 9960 tgcccctcca gaaacagaag gagtgtatga cattgataaa atcaaagaac agagtgggct 10020 ttacaggttt catatgggag ggattgaggg gtggtgccaa aagttgtgga ctatggaggc 10080 tgtctctttg ttagatgtgg tatcagtcaa aaaccgtgtc caactaacat cattgttaaa 10140 cggagataat caatctattg atgttagcaa acctgttagg ttgtcacaag gagttgatga 10200 agttaaagct gactatagcc tggcagtgaa aatgttaaaa gaaataagaa atgcttacaa 10260 agatataggg cacaagttaa aagagggaga gacatatata tctagagacc tacaatttat 10320 gagcaaagtc attcagtcag aaggtgtgat gcatccatca ccgataaaga agattttgag 10380 ggttgggcca tggatcaata ctatcctaga tgacatcaaa accagtgcag agtcaatagg 10440 aagcctgtgt caagagttag agtttagagg cgaaagcctc ttggtcagcc tcatcctaag 10500 gaatttttgg ctatatgaat tatggatgca tgaatctaaa agtcatccac ttgcagggaa 10560 gcagctatac agacagctga gcaagacatt agcaataact caaaagttct ttggaataac 10620 aaaagaaact gatgttgtta atctgtggat gaatgttcca atgcagtttg gtggaggtga 10680 tcctgtagtg ctatataggt cattttaccg gaggacacca gatttcttga ctgaagcagt 10740 tagccatatg agtgtactac tcaaagtgta tgggaaagcg aaagagggat caaagaaaga 10800 ttttttcaaa gcattattat cagtggacaa aaacaagagg gctactctga ccacattaat 10860 gagagaccct caagcagtgg gatcagaaag acaggcaaga gttactagtg aaataaatag 10920 agcagcagtc acaagtgtcc taagcctatc acctaatcag cttttctgtg acagtgcaat 10980 acactacagc aggaatgaag aagaagttgg gttaatagcc caaaacataa caccagtcta 11040 cccacatggg ttgagggtgc tgtatgagtc attgccattc cacaaggcag aaaaagttgt 11100 aaacatgata tctggaacaa aatctatcac aaacttgcta caaaggacgt cagcaatcaa 11160 tggagaagac attgatagag cagtctcaat gatgttggag aatctagggt tgctctctag 11220 gatactatct gtgtgccaag atgatataac cttacctacc aaagcgaatg gtgatctgat 11280 atgttgtcaa gtctctagga ctttgagaga aaggtcctgg gataacatgg aaattgttgg 11340 agtcacctca ccgagtatag ttacatgtat gaacatagtg tattccagca gctctcaact 11400 aaaaggaata acaattgaaa agttcagcac agataaaact acaagaggtc aaagaggacc 11460 aaaaagtcct tgggttgggt ccagcacaca agagaaaaaa ttggttcctg tttacaacag 11520 gcaaatcctt tcaaagcaac agaaagaaca actagaggca atcgggaaac taagatgggt 11580 ttataagggg actcaagggt taaggaggtt gttagataaa atctgcatag ggagcttagg 11640 gatcagttac aagaatgtta aaccactctt gccaagattt atgagtgtta acttcctaca 11700 cagactttcc gtcagcagta gaccaatgga atttccagca tctgtccctg cttacagaac 11760 gaccaattac cattttgaca caagtcctgt aaatcagact ctgagtgaaa gatttgggaa 11820 tgaggatatc aacttggtgt ttcaaaatgc tatcagctgt gggataagtg tgatgagtgt 11880 agtggaacaa cttacaggca gaagccctaa acaattagta atgattcccc aactagaaga 11940 aattgacata atgcctccgc ctgtcttttt aggaaaattt gattacaaac tggtagaaaa 12000 gatatcttca gaccaacaca ttttcagccc tgacaaattg gacttagtga ctctaggtaa 12060 aatgttaatg ccttcaacaa gtggagcaaa gtctgaccaa ttttggaaca gaaaagaaaa 12120 cttctttcat ggcaacaatt tggtagagtc tctatctgca gcattggctt gtcattggtg 12180 cggaatctta actgaacagt gtaacgagaa caatattttt agaagagaat ggggtgatgg 12240 ttttgttacg gatcatgcct tcatagattt caaaacattt gttggtgtat ttaagaccaa 12300 actattgtgt gggtggggat ccaggggggg agatattaaa gatagagaca tgatagatga 12360 atctattgac aaattaataa gagttgacaa ctcgttctgg aggatgttta gtaaagtgat 12420 acttgaacct aaagtgagga aaagggtaat gctttttgat gtgaaaatcc tatcacttgt 12480 gggctatgca ggatttaaaa attggtttat tgatcacttg agatctagtg acttgtgtga 12540 agtgccatgg gttgtcaatg ctgatagtga aattgtagag gtgtctgctg tgaaaatata 12600 tttacagttg ctgagagtga gttctccttt gagaatcaca gtgttaaatt actcagacat 12660 ggcccatgct atcaccaggc taataagaag gaaatcaatg catgataatg taccttcaat 12720 atctaggaca ctgtcacctg cagagttagc tcctgtagtt gaaccaactg tgcagatgaa 12780 cttgttccct aagatcacat tcgaaagatt gaagaattac gaaactgtgt caggatccac 12840 tagaggaaag ttgacaagaa attacatggt aatgttgcct tggcagcata tcaatagatt 12900 caattttgta ttcagctcta ctggttgcaa aataagtgtc aaagcatgta ttggaaggtt 12960 gattcaagac ttaaatccga cagtttttta ttttgtagga gaaggagccg gcaattggat 13020 ggcaagaaca gcctgtgagt atccaaatgc aaagtttgtt tacaggagcc ttaaagatga 13080 tttggaccat catttccctt tggagtttca gagagtcctg gggaacatga atagagttat 13140 agatggtgga gaaggcctgt ctatggacac aacagatgca actcagaaaa ctcattggga 13200 tctgatacat agaatttgta aagatgcact gctgattaca ttgtgtgatg ctgaatttaa 13260 agacagggat gattttttca agatggtgac actatggaga aagcatgttt tgtcgtgtag 13320 aatatgtaca acctatggaa cagatctcta cctgtttgca aaatatcatg caaaagagca 13380 aagcataaaa cttccctatt ttgttagatc aattgccaca tatgtcatgc aaggcagtaa 13440 actgtcatgg atccgagtgt tatgtccttc taacacttgg ccaccacaat aacctaccat 13500 gtcacgggga ggtacagagc tccaagttaa aattggctgt gtgcaatgat ttcagcattc 13560 ctaggaaagt agaagtgaag gctgttgagg caaactgcaa atctctgctt tccggcctaa 13620 ggacacctat aaatagagca gaattagatc gacaaaagaa gatgttgaca ctaagaagtt 13680 atcattcatc agttgcaaca gttggaggca gcagggtcat tgaatcaaaa tggttgagca 13740 agaaggctac cactataatt gaatggttag aacatatctt gaattcccca aaaggggagt 13800 taaactatga tttttttgag gcactagaga acacctatcc aaatatggtt aaattattag 13860 ataatcttgg cagtgctgaa cttaaaaagc taatcaaagt gacaggttac atgctgatga 13920 gtaagaagta atggaaggaa attaccttaa gaaattacct atggtgaagg cttaaaactt 13980 acatatccgt gctggaaaat attaaagtaa tagttactta aatttagtaa tctggatatg 14040 aagcgcacaa ctagcaatta gttattaaaa a 14071 //