ID   D01075; SV 1; circular; genomic RNA; STD; VRL; 1682 BP.
XX
AC   D01075;
XX
DT   26-AUG-1992 (Rel. 33, Created)
DT   27-FEB-2006 (Rel. 86, Last updated, Version 7)
XX
DE   Hepatitis delta virus genomic RNA, complete genome.
XX
KW   .
XX
OS   Hepatitis delta virus
OC   Viruses; Riboviria; Deltavirus.
XX
RN   [1]
RP   1-1682
RX   DOI; 10.1038/329343a0.
RX   PUBMED; 3627276.
RA   Makino S., Chang M.-F., Shieh C.-K., Kamahora T., Vannier D.M.,
RA   Govindarajan S., Lai M.M.;
RT   "Molecular cloning and sequencing of a human hepatitis delta (delta) virus
RT   RNA";
RL   Nature 329(6137):343-346(1987).
XX
RN   [2]
RP   1-1682
RX   PUBMED; 2374010.
RA   Saldanha J.A., Thomas H.C., Monjardino J.P.;
RT   "Cloning and sequencing of RNA of hepatitis delta virus isolated from human
RT   serum";
RL   J. Gen. Virol. 71:1603-1606(1990).
XX
DR   MD5; 000b81fafd6750946ad64560c96d8884.
DR   EuropePMC; PMC2952689; 20855099.
DR   EuropePMC; PMC3294742; 17073101.
DR   EuropePMC; PMC369207; 14963156.
DR   RFAM; RF00094; HDV_ribozyme.
XX
CC   Three ORFs are present on the genomic strand and two on the
CC   antigenomic strand. The longest ORF on the antigenomic strand has
CC   been shown to code for the delta antigen (HDAg). The other ORFs do
CC   not appear to code for any functional proteins.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1682
FT                   /organism="Hepatitis delta virus"
FT                   /mol_type="genomic RNA"
FT                   /clone="D380, D600, D75, D280, D54, D4, D20, D33, D69,
FT                   462b, 702b, 572c, 772c, 462c"
FT                   /note="HindIII site of chimpanzee-derived HDV RNA"
FT                   /note="isolated from human serum"
FT                   /note="synonym: Hepatitis D virus"
FT                   /db_xref="taxon:12475"
FT   misc_feature    153..157
FT                   /note="viroid consensus sequence"
FT   misc_feature    685..686
FT                   /note="self-splicing site"
FT   misc_feature    735..755
FT                   /note="palindromic sequence"
FT   misc_feature    complement(784..785)
FT                   /note="self-splicing site"
FT   misc_feature    942..946
FT                   /note="viroid consensus sequence"
FT   CDS             complement(1013..1600)
FT                   /codon_start=1
FT                   /product="delta antigen"
FT                   /note="HDAg"
FT                   /db_xref="GOA:P0C6L3"
FT                   /db_xref="GOA:P29996"
FT                   /db_xref="InterPro:IPR002506"
FT                   /db_xref="InterPro:IPR027403"
FT                   /db_xref="InterPro:IPR037517"
FT                   /db_xref="UniProtKB/Swiss-Prot:P0C6L3"
FT                   /db_xref="UniProtKB/Swiss-Prot:P29996"
FT                   /protein_id="BAA00874.1"
FT                   /translation="MSRPEGRKNRGGREEVLEQWVSGRKKLEELERDLRKVKKKIKKLE
FT                   DEHPWLGNIKGILGKKDKDGEGAPPAKRARTDQMEVDSGPRKRPSRGGFTDKERQDHRR
FT                   RKALENKRKQLSAGGKNLSKEEEEELRRLTEEDERRERRIAGPQVGGVNPLEGGTRGAP
FT                   GGGFVPSMQGVPESPFTRTGEGLDIRGSQGFP"
FT   misc_feature    1478..1483
FT                   /note="viroid consensus sequence"
XX
SQ   Sequence 1682 BP; 339 A; 504 C; 485 G; 354 T; 0 other;
     atgagccaag ttccgaacaa ggattcgcgg ggaggataga tcagcgcccg agaggggtga        60
     gtcggtaaag agcattggaa cgtcggagat acaactccca agaaggaaaa aagagaaagc       120
     aagaagcgga tgaatttccc cataacgcca gtgaaactct aggaagggga aagagggaag       180
     gtggaagaga aggaggcggg cctcccgatc cgaggggccc ggcggccaag tttggaggac       240
     actccggccc gaagggttga gagtacccca gagggaggaa gccacacgga gtagaacaga       300
     gaaatcacct ccagaggacc ccttcagcga acagagagcg catcgcgaga gggagtagac       360
     catagcgata ggaggggatg ctaggagttg ggggagaccg aagcgaggag gaaagcaaag       420
     agagcagcgg ggctagcagg tgggtgttcc gccccccgag aggggacgag tgaggcttat       480
     cccggggaac tcgacttatc gtccccacat agcagactcc cggaccccct ttcaaagtga       540
     ccgagggggg tgactttgaa cattggggac cagtggagcc atgggatgct cctcccgatt       600
     ccgcccaagc tccttccccc caagggtcgc ccaggaatgg cgggacccca ctctgcaggg       660
     tccgcgttcc atcctttctt acctgatggc cggcatggtc ccagcctcct cgctggcgcc       720
     ggctgggcaa cattccgagg ggaccgtccc ctcggtaatg gcgaatggga cccacaaatc       780
     tctctagctt cccagagaga agcgagagaa aagtggctct cccttagcca tccgagtgga       840
     cgtgcgtcct ccttcggatg cccaggtcgg accgcgagga ggtggagatg ccatgccgac       900
     ccgaagagga aagaaggacg cgagacgcaa acctgcgagt ggaaacccgc tttattcact       960
     ggggtcgaca actctgggga gaggagggag ggtcggctgg gaagagtata tcctatggga      1020
     atccctggct tccccttatg tccagtccct ccccggtccg agtaaagggg gactccggga      1080
     ctccttgcat gctggggacg aagccgcccc cgggcgctcc cctcgttcca ccttcgaggg      1140
     ggttcacacc cccaacctgc gggccggcta ttcttctttc ccttctctcg tcttcctcgg      1200
     tcaacctcct aagttcctct tcctcctcct tgctgaggtt ctttcccccc gccgatagct      1260
     gctttctctt gttctcgagg gccttccttc gtcggtgatc ctgcctctcc ttgtcggtga      1320
     atcctcccct ggaaggcctc ttcctaggtc cggagtctac ttccatctgg tccgttcggg      1380
     ccctcttcgc cgggggagcc ccctctccat ccttatcttt ctttccgaga attcctttga      1440
     tgtttcccag ccagggatgt tcatcctcaa gtttcttgat tttcttctta accttccgga      1500
     ggtctctctc gagttcctct aacttctttc ttccgctcac ccactgctcg agaacctctt      1560
     ctctcccccc gcggtttttc cttccttcgg gccggctcat cttcgactag aggcgacggt      1620
     cctcagtact cttactcttt tctgtaaaga ggagactgct ggccctgtcg cccaagttcg      1680
     ag                                                                     1682
//