Dbfetch
ID M18370; SV 1; linear; genomic RNA; STD; VRL; 10976 BP. XX AC M18370; XX DT 20-FEB-1989 (Rel. 18, Created) DT 17-APR-2005 (Rel. 83, Last updated, Version 5) XX DE Japanese encephalitis virus (strain JaOArS982), complete genome. XX KW C gene; E protein; M protein; nonstructural protein. XX OS Japanese encephalitis virus OC Viruses; Riboviria; Flaviviridae; Flavivirus. XX RN [1] RP 1-10976 RX DOI; 10.1016/0042-6822(87)90144-9. RX PUBMED; 3686827. RA Sumiyoshi H., Mori C., Fuke I., Morita K., Kuhara S., Kondou J., RA Kikuchi Y., Nagamatu H., Igarashi A.; RT "Complete nucleotide sequence of the Japanese encephalitis virus genome RT RNA"; RL Virology 161(2):497-510(1987). XX DR MD5; 500f979e2240d1f96807e1097eab4883. DR EuropePMC; PMC1265912; 16223950. DR EuropePMC; PMC1698363; 17005741. DR EuropePMC; PMC2173888; 17971212. DR EuropePMC; PMC2600181; 18258114. DR EuropePMC; PMC2663380; 19141845. DR EuropePMC; PMC2714537; 19575816. DR EuropePMC; PMC2727306; 19523285. DR EuropePMC; PMC2741316; 19645300. DR EuropePMC; PMC3196406; 21697481. DR EuropePMC; PMC3249550; 22033595. DR EuropePMC; PMC3352935; 22615830. DR EuropePMC; PMC3372344; 17283629. DR EuropePMC; PMC3683586; 22840606. DR EuropePMC; PMC4336650; 25604524. DR EuropePMC; PMC4557254; 26261169. DR EuropePMC; PMC4760945; 26895440. DR EuropePMC; PMC5110185; 27654301. DR EuropePMC; PMC5640849; 28814522. DR EuropePMC; PMC5987586; 29991925. DR EuropePMC; PMC6206487; 30158291. DR EuropePMC; PMC88049; 11326014. DR GOA; P0DOH8. DR InterPro; IPR000069; Env_glycoprot_M_flavivir. DR InterPro; IPR000336; Flavivir/Alphavir_Ig-like_sf. DR InterPro; IPR011998; Glycoprot_cen/dimer. DR InterPro; IPR014756; Ig_E-set. DR InterPro; IPR027287; Flavi_E_Ig-like. DR InterPro; IPR036253; Glycoprot_cen/dimer_sf. DR InterPro; IPR037172; Flavi_capsidC_sf. DR InterPro; IPR038345; Flavi_E_Stem/Anchor_dom_sf. DR InterPro; IPR038688; Flavi_propep_sf. DR RFAM; RF00185; Flavi_CRE. DR RFAM; RF00465; JEV_hairpin. DR RFAM; RF00525; Flavivirus_DB. DR RFAM; RF00617; cHP. DR RFAM; RF01415; Flavivirus_SLIV. DR RFAM; RF01768; flavi_FSE. DR UniProtKB/Swiss-Prot; P0DOH8; POLS_JAEVJ. XX CC Draft entry and computer-readable sequence for [1] kindly submitted CC by H.Sumiyoshi, 31-AUG-1989. XX FH Key Location/Qualifiers FH FT source 1..10976 FT /organism="Japanese encephalitis virus" FT /strain="JaOArS982" FT /mol_type="genomic RNA" FT /db_xref="taxon:11072" FT CDS 96..10394 FT /codon_start=1 FT /note="JEV polyprotein" FT /db_xref="GOA:P32886" FT /db_xref="InterPro:IPR000069" FT /db_xref="InterPro:IPR000208" FT /db_xref="InterPro:IPR000336" FT /db_xref="InterPro:IPR000404" FT /db_xref="InterPro:IPR000487" FT /db_xref="InterPro:IPR000752" FT /db_xref="InterPro:IPR001122" FT /db_xref="InterPro:IPR001157" FT /db_xref="InterPro:IPR001528" FT /db_xref="InterPro:IPR001650" FT /db_xref="InterPro:IPR001850" FT /db_xref="InterPro:IPR002535" FT /db_xref="InterPro:IPR002877" FT /db_xref="InterPro:IPR007094" FT /db_xref="InterPro:IPR009003" FT /db_xref="InterPro:IPR011492" FT /db_xref="InterPro:IPR011998" FT /db_xref="InterPro:IPR014001" FT /db_xref="InterPro:IPR014412" FT /db_xref="InterPro:IPR014756" FT /db_xref="InterPro:IPR026470" FT /db_xref="InterPro:IPR026490" FT /db_xref="InterPro:IPR027287" FT /db_xref="InterPro:IPR027417" FT /db_xref="InterPro:IPR029063" FT /db_xref="InterPro:IPR036253" FT /db_xref="InterPro:IPR037172" FT /db_xref="InterPro:IPR038055" FT /db_xref="InterPro:IPR038302" FT /db_xref="InterPro:IPR038345" FT /db_xref="InterPro:IPR038688" FT /db_xref="PDB:2HYL" FT /db_xref="PDB:2I84" FT /db_xref="PDB:5YWO" FT /db_xref="PDB:5YWP" FT /db_xref="UniProtKB/Swiss-Prot:P32886" FT /protein_id="AAA81554.1" FT /translation="MTKKPGGPGKNRAINMLKRGLPRVFPLVGVKRVVMSLLDGRGPVR FT FVLALITFFKFTALAPTKALLGRWKAVEKSVAMKHLTSFKRELGTLIDAVNKRGRKQNK FT RGGNEGSIMWLASLAVVIAYAGAMKLSNFQGKLLMTINNTDIADVIVIPTSKGENRCWV FT RAIDVGYMCEDTITYECPKLTMGNDPEDVDCWCDNQEVYVQYGRCTRTRHSKRSRRSVS FT VQTHGESSLVNKKEAWLDSTKATRYLMKTENWIIRNPGYAFLAATLGWMLGSNNGQRVV FT FTILLLLVAPAYSFNCLGMGNRDFIEGASGATWVDLVLEGDSCLTIMANDKPTLDVRMI FT NIEASQLAEVRSYCYHASVTDISTVARCPTTGEAHNEKRADSSYVCKQGFTDRGWGNGC FT GLFGKGSIDTCAKFSCTSKAIGRTIQPENIKYEVGIFVHGTTTSENHGNYSAQVGASQA FT AKFTITPNAPSITLKLGDYGEVTLDCEPRSGLNTEAFYVMTVGSKSFLVHREWFHDLAL FT PWTSPSSTAWRNRELLMEFEEAHATKQSVVALGSQEGGLHQALAGAIVVEYSSSVKLTS FT GHLKCRLKMDKLALKGTTYGMCTEKFSFAKNPADTGHGTVVIELSYSGSDGPCKIPIVS FT VASLNDMTPVGRLVTVNPFVATSSANSKVLVEMEPPFGDSYIVVGRGDKQINHHWHKAG FT STLGKAFSTTLKGAQRLAALGDTAWDFGSIGGVFNSIGKAVHQVFGGAFRTLFGGMSWI FT TQGLMGALLLWMGVNARDRSIALAFLATGGVLVFLATNVHADTGCAIDITRKEMRCGSG FT IFVHNDVEAWVDRYKYLPETPRSLAKIVHKAHKEGVCGVRSVTRLEHQMWEAVRDELNV FT LLKENAVDLSVVVNKPVGRYRSAPKRLSMTQEKFEMGWKAWGKSILFAPELANSTFVVD FT GPETKECPDEHRAWNSMQIEDFGFGITSTRVWLKIREESTDECDGAIIGTAVKGHVAVH FT SDLSYWIESRYNDTWKLERAVFGEVKSCTWPETHTLWGDGVEESELIIPHTIAGPKSKH FT NRREGYKTQNQGPWDENGIVLDFDYCPGTKVTITEDCGKRGPSVRTTTDSGKLITDWCC FT RSCSLPPLRFRTENGCWYGMEIRPVRHDETTLVRSQVDAFNGEMVDPFQLGLLVMFLAT FT QEVLRKRWTARLTIPAVLGALLVLMLGGITYTDLARYVVLVAAAFAEANSGGDVLHLAL FT IAVFKIQPAFLVMNMLSTRWTNQENVVLVLGAALFQLASVDLQIGVHGILNAAAIAWMI FT VRAITFPTTSSVTMPVLALLTPGMRALYLDTYRIILLVIGICSLLQERKKTMAKKKGAV FT LLGLALTSTGWFSPTTIAAGLMVCNPNKKRGWPATEFLSAVGLMFAIVGGLAELDIESM FT SIPFMLAGLMAVSYVVSGKATDMWLERAADISWEMDAAITGSSRRLDVKLDDDGDFHLI FT DDPGVPWKVWVLRMSCIGLAALTPWAIVPAAFGYWLTLKTTKRGGVFWDTPSPKPCSKG FT DTTTGVYRIMARGILGTYQAGVGVMYENVFHTLWHTTRGAAIMSGEGKLTPYWGSVKED FT RIAYGGPWRFDRKWNGTDDVQVIVVEPGKAAVNIQTKPGVFRTPFGEVGAVSLDYPRGT FT SGSPILDSNGDIIGLYGNGVELGDGSYVSAIVQGDRQEEPVPEAYTPNMLRKRQMTVLD FT LHPGSGKTRKILPQIIKDAIQQRLRTAVLAPTRVVAAEMAEALRGLPVRYQTSAVQREH FT QGNEIVDVMCHATLTHRLMSPNRVPNYNLFVMDEAHFTDPASIAARGYIATKVELGEAA FT AIFMTATPPGTTDPFPDSNAPIHDLQDEIPDRAWSSGYEWITEYAGKTVWFVASVKMGN FT EIAMCLQRAGKKVIQLNRKSYDTEYPKCKNGDWDFVITTDISEMGANFGASRVIDCRKS FT VKPTILEEGEGRVILGNPSPITSASAAQRRGRVGRNPNQVGDEYHYGGATSEDDSNLAH FT WTEAKIMLDNIHMPNGLVAQLYGPEREKAFTMDGEYRLRGEEKKNFLELLRTADLPVWL FT AYKVASNGIQYTDRRWCFDGPRTNAILEDNTEVEIVTRMGERKILKPRWLDARVYADHQ FT ALKWFKDFAAGKRSAISFIEVLGRMPEHFMGKTREALDTMYLVATAEKGGKAHRMALEE FT LPDALETITLIVAITVMTGGFFLLMMQRKGIGKMGLGALVLTLATFFLWAAEVPGTKIA FT GTLLIALLLMVVLIPEPEKQRSQTDNQLAVFLICVLTVVGVVAANEYGMLEKTKADLKS FT MFVGKTQASGLTGLPSMALDLRPATAWALYGGSTVVLTPLLKHLITSEYVTTSLASINS FT QAGSLFVLPRGVPFTDLDLTVGLVFLGCWGQITLTTFLTAMVLATLHYGYMLPGWQAEA FT LRAAQRRTAAGIMKNAVVDGMVATDVPELERTTPLMQKKVGQVLLIGVSVAAFLVNPNV FT TTVREAGVLVTAATLTLWDNGASAVWNSTTATGLCHVMRGSYLAGGSIAWTLIKNADKP FT SLKRGRPGGRTLGEQWKEKLNAMSREEFFKYRREAIIEVDRTEARRARRENNIVGGHPV FT SRGSAKLRWLVEKGFVSPIGKVIDLGCGRGGWSYYAATLKKVQEVRGYTKGGAGHEEPM FT LMQSYGRNLVSLKSGVDVFYKPSEPSDTLFCDIGESSPSPEVEEQRTLRVLEMTSDWLH FT RGPREFCIKVLCPYMPKVIEKMEVLQRRFGGGLVRLPLSRNSNHEMYWVSGAAGNVVHA FT VNMTSQVLLGRMDRTVWRGPKYEEDVNLGSGTRAVGKGEVHSNQEKIKKRIQKLKEEFA FT TTWHKDPEHPYRTWTYHGSYEVKATGSASSLVNGVVKLMSKPWDAIANVTTMAMTDTTP FT FGQQRVFKEKVDTKAPEPPAGAKEVLNETTNWLWAHLSREKRPRLCTKEEFIKKVNSNA FT ALGAVFAEQNQWSTAREAVDDPRFWEMVDEERENHLRGECHTCIYNMMGKREKKPGEFG FT KAKGSRAIWFMWLGARYLEFEALGFLNEDHWLSRENSGGGVEGSGVQKLGYILRDIAGK FT QGGKMYADDTAGWDTRITRTDLENEAKVLELLDGEHRMLARAIIELTYRHKVVKVMRPA FT AEGKTVMDVISREDQRGSGQVVTYALNTFTNIAVQLVRLMEAEGVIGPQHLEQLPRKTK FT IAVRTWLFENGEERVTRMAISGDDCVVKPLDDRFATALHFLNAMSKVRKDIQEWKPSHG FT WHDWQQVPFCSNHFQEIVMKDGRSIVVPCRGQDELIGRARISPGAGWNVKDTACLAKAY FT AQMWLLLYFHRRDLRLMANAICSAVPVDWVPTGRTSWSIHSKGEWMTTEDMLQVWNRVW FT IEENEWMMDKTPITSWTDVPYVGKREDIWCGSLIGTRSRATWAENIYAAINQVRAVIGK FT ENYVDYMTSLRRYEDVLIQEDRVI" FT mat_peptide 99..476 FT /note="C protein" FT sig_peptide 477..752 FT /note="M protein signal peptide" FT mat_peptide 753..977 FT /note="M protein" FT mat_peptide 978..2477 FT /note="E protein" FT mat_peptide 2478..4214 FT /note="NS1 protein" FT mat_peptide 4215..4607 FT /note="NS 2b protein" FT mat_peptide 4608..6464 FT /note="NS3 protein" FT mat_peptide 6465..7331 FT /note="NS 4a protein" FT mat_peptide 7332..10391 FT /note="NS 4b protein" FT misc_feature 10828..10847 FT /note="conserved region" FT misc_feature 10866..10888 FT /note="conserved region" XX SQ Sequence 10976 BP; 3047 A; 2531 C; 3113 G; 2285 T; 0 other; agaagtttat ctgtgtgaac ttcttggctt agtatcgttg agaagaatcg agagattagt 60 gcagtttaaa cagtttttta gaacggaaga taaccatgac taaaaaacca ggagggcccg 120 gtaaaaaccg ggctatcaat atgctgaaac gcggcctacc ccgcgtattc ccactagtgg 180 gagtgaagag ggtagtaatg agcttgttgg acggcagagg gccagtacgt ttcgtgctgg 240 ctcttatcac gttcttcaag tttacagcat tagccccgac caaggcgctt ttaggccgat 300 ggaaagcagt ggaaaagagt gtggcaatga aacatcttac tagtttcaaa cgagaacttg 360 gaacactcat tgacgccgtg aacaagcggg gcagaaaaca aaacaaaaga ggaggaaatg 420 aaggctcaat catgtggctc gcaagcttgg cagttgtcat agcttacgca ggagcaatga 480 agttgtcgaa tttccagggg aagcttttga tgaccatcaa caacacggac attgcagacg 540 ttatcgtgat tcccacctca aaaggagaga acagatgctg ggtccgggca atagacgtcg 600 gctacatgtg tgaggacact atcacgtacg aatgtcctaa gctcaccatg ggcaatgatc 660 cagaggatgt ggattgctgg tgtgacaacc aagaagtcta cgtccaatat ggacggtgca 720 cgcggaccag gcattccaag cgaagcagga gatccgtgtc ggtccaaaca catggggaga 780 gttcactagt gaataaaaaa gaggcttggc tggattcaac gaaagccaca cggtatctca 840 tgaaaactga gaactggatc ataaggaatc ctggctatgc tttcctggcg gcgacacttg 900 gctggatgct tggcagtaac aacggtcaac gcgtggtatt taccatcctc ctgctgttgg 960 tcgctccggc ttacagtttt aattgtctgg gaatgggcaa tcgtgacttc atagaaggag 1020 ccagtggagc cacttgggtg gacttggtgc tagaaggaga tagctgcttg acaatcatgg 1080 caaacgacaa accaacattg gacgtccgca tgattaacat cgaagctagc caacttgctg 1140 aggtcagaag ttactgctat catgcttcag tcactgacat ctcgacggtg gctcggtgcc 1200 ccacgactgg agaagctcac aacgagaagc gagctgatag tagctatgtg tgcaaacaag 1260 gcttcactga tcgtgggtgg ggcaacggat gtggactttt cgggaaggga agcattgaca 1320 catgtgcaaa attctcctgc accagcaaag cgattggaag aacaatccag ccagaaaaca 1380 tcaaatacga agttggcatt tttgtgcatg gaaccaccac ttcggaaaac catgggaatt 1440 attcagcgca agttggggcg tcccaggcgg caaagtttac aataacaccc aatgctcctt 1500 cgataaccct caaacttggt gactacggag aagtcacgct ggactgtgag ccaaggagtg 1560 gactgaacac tgaagcgttt tacgtcatga ccgtggggtc aaagtcattt ctggtccata 1620 gggaatggtt tcatgacctc gctctcccct ggacgtcccc ttcgagcaca gcgtggagaa 1680 acagagaact cctcatggaa tttgaagagg cgcacgccac aaaacagtcc gttgttgctc 1740 ttgggtcaca ggaaggaggc ctccatcagg cgttggcagg agccatcgtg gtggagtact 1800 caagctcagt gaagttaaca tcaggccacc tgaaatgtag gctgaaaatg gacaaactgg 1860 ctctgaaagg cacaacctat ggcatgtgta cagaaaaatt ctcgttcgcg aaaaatccgg 1920 cggacactgg ccacggaaca gttgtcattg aactatccta ctctgggagt gatggcccct 1980 gcaaaattcc gattgtctcc gttgcgagcc tcaatgacat gacccccgtt gggcggctgg 2040 tgacagtgaa ccctttcgtc gcgacttcca gtgccaactc aaaggtgctg gtcgagatgg 2100 aacccccctt cggagactcc tacatcgtgg ttgggagggg agacaagcag atcaaccacc 2160 attggcacaa agctggaagc acgctaggca aggccttttc aacaactttg aagggagctc 2220 aaagactggc agcgttgggc gacacagcct gggactttgg ctccattgga ggggtcttca 2280 actccatagg aaaagccgtt caccaagtgt ttggtggtgc cttcagaaca ctctttgggg 2340 gaatgtcttg gatcacacaa gggctaatgg gtgccctact actctggatg ggcgtcaacg 2400 cacgagaccg atcaattgct ttggccttct tagccacagg aggtgtgctc gtgttcttag 2460 cgaccaatgt gcatgctgac actggatgtg ccattgacat cacaagaaaa gagatgagat 2520 gtggaagtgg catctttgtg cacaacgacg tggaagcctg ggtggacagg tataaatact 2580 tgccagaaac gcccagatcc ctagcgaaga tcgtccacaa agcgcacaag gaaggcgtgt 2640 gcggagtcag atctgtcact agattggagc accaaatgtg ggaagccgta cgggacgaat 2700 tgaacgtcct gctcaaagag aatgcagtgg acctcagtgt ggttgtgaac aagcccgtgg 2760 gaagatatcg ctcagcccct aaacgcctat ccatgacgca agagaagttt gaaatgggct 2820 ggaaagcatg gggaaaaagc attctctttg ccccggaatt ggctaactcc acatttgtcg 2880 tagatggacc tgagacaaag gaatgccctg atgagcatag agcttggaac agcatgcaaa 2940 tcgaagactt cggctttggc atcacatcaa cccgtgtgtg gctgaaaatt agagaggaga 3000 gcactgacga gtgtgatgga gcgatcatag gcacggctgt caaaggacat gtggcagtcc 3060 atagtgactt gtcgtactgg attgagagtc gctacaacga cacatggaaa cttgagaggg 3120 cagtctttgg agaggtcaaa tcttgcactt ggccagagac acacaccctt tggggagatg 3180 gtgttgagga aagtgaactc atcattccgc ataccatagc cggaccaaaa agcaagcaca 3240 atcggaggga agggtataag acacaaaacc agggaccttg ggatgagaat ggcatagtct 3300 tggactttga ctattgccca gggacgaaag tcaccattac agaggactgt ggcaagagag 3360 gcccttcggt cagaaccact actgacagtg gaaagttgat tactgactgg tgctgtcgca 3420 gttgctccct tccgccccta cgattccgga cagaaaatgg ctgctggtac ggaatggaaa 3480 tcagacctgt caggcatgat gaaacaacac tcgttagatc acaggttgat gctttcaatg 3540 gtgaaatggt tgaccctttt cagctgggcc ttctggtgat gtttctggcc acccaggagg 3600 tccttcgcaa gaggtggacg gccagattga ccattcctgc ggttttgggg gccctacttg 3660 tgctgatgct tgggggcatc acttacactg atttggcgag gtatgtggtg ctagtcgctg 3720 ccgctttcgc agaggccaac agtggaggag acgtcctgca tcttgctttg attgccgttt 3780 ttaagatcca accagcgttt ctagtgatga acatgcttag cacgagatgg acgaaccaag 3840 aaaacgtggt cctggtccta ggggctgcct tgtttcaact ggcctcagta gatctgcaaa 3900 taggagtcca cggaatcctg aatgccgccg ctatagcatg gatgattgtc cgagcgatca 3960 ccttccccac aacctcctcc gtcaccatgc cagtcttagc gcttctaacc ccgggaatga 4020 gggctctata cctagacact tacagaatca tcctcctcgt catagggatt tgctccctgc 4080 tgcaagagag gaaaaagacc atggcaaaaa agaaaggagc tgtactcttg ggcttagcgc 4140 tcacatccac tggatggttc tcgcccacca ctatagctgc cggactaatg gtctgcaacc 4200 caaacaagaa gagagggtgg ccagccactg agtttttgtc ggcagttgga ttgatgtttg 4260 ccatcgtagg tggcttggcc gagttggata ttgaatccat gtcaataccc ttcatgctgg 4320 caggtctcat ggcagtgtcc tacgtggtgt caggaaaagc aacagatatg tggcttgaac 4380 gggccgccga catcagctgg gagatggatg ctgcaatcac aggaagtagt cggaggctgg 4440 atgtgaaact ggatgatgac ggagattttc acttgattga tgatcccggt gttccatgga 4500 aggtctgggt cctgcgcatg tcttgtattg gcttagccgc cctcacgcct tgggccatcg 4560 ttcccgccgc tttcggttat tggctcactt taaaaacaac aaaaagaggg ggcgtgtttt 4620 gggacacgcc atccccaaaa ccttgctcaa aaggagacac tactacagga gtctaccgaa 4680 ttatggctag agggattctt ggcacttacc aggccggcgt cggagtcatg tacgagaatg 4740 ttttccacac actatggcac acaactagag gagcagccat tatgagtgga gaaggaaaat 4800 tgacgccata ctggggtagt gtgaaagaag accgcatagc ttacggaggc ccatggaggt 4860 ttgaccgaaa atggaatgga acagatgacg tgcaagtgat cgtggtagaa ccggggaagg 4920 ctgcagtaaa catccagaca aaaccaggag tgtttcggac tcccttcggg gaggttgggg 4980 ctgttagtct ggattacccg cgaggaacat ccggctcacc cattctggat tctaatggag 5040 acatcatagg cctatacggc aatggagttg agcttggcga tggctcatac gtcagcgcca 5100 tcgtgcaggg tgaccgtcag gaggaaccag tcccagaagc ttacacccca aacatgttga 5160 gaaagagaca gatgactgtg ctagatttgc accctggctc agggaagacc aggaaaattc 5220 tgccacagat aatcaaggac gccatccagc agcgcctaag aacagctgtg ctggcaccga 5280 cgcgggtggt agcagcagaa atggcagaag ctttgagagg gctcccagtg cgatatcaaa 5340 cttcagcagt gcagagagag caccaaggga atgaaatagt ggatgtgatg tgccacgcca 5400 ctctgaccca tagactgatg tcaccgaaca gagtgcccaa ctacaaccta tttgtcatgg 5460 atgaagctca tttcactgac ccagccagca tagccgcacg aggatacatt gctaccaagg 5520 tggaattagg ggaggcagca gccatcttca tgacagcgac cccgcctgga accacggatc 5580 cttttcctga ctcaaatgcc ccaatccatg atttgcaaga tgagatacca gacagggcat 5640 ggagcagtgg atacgaatgg atcacagaat atgcgggcaa aaccgtgtgg tttgtggcga 5700 gcgtaaaaat ggggaatgag attgcaatgt gcctccaaag agcggggaaa aaggtcatcc 5760 aactcaaccg caagtcctat gatacagaat acccaaaatg taagaatgga gactgggact 5820 ttgtcattac caccgacatc tctgaaatgg gggccaactt cggtgcgagc agggtcatcg 5880 actgtagaaa gagcgtgaaa cccaccatct tagaagaggg agaaggcaga gtcatcctcg 5940 gaaacccatc tcccataacc agtgcaagcg cagctcaacg gaggggcaga gtaggcagaa 6000 accccaacca agttggagat gaatatcact atgggggggc taccagtgaa gatgacagta 6060 acctagccca ttggacagag gcaaagatca tgttagacaa catacacatg cccaatggac 6120 tggtggccca gctctatgga ccagagaggg aaaaggcttt tacaatggat ggtgaatacc 6180 gtctcagagg tgaagaaaag aaaaacttct tggagctgct taggacggct gacctcccgg 6240 tgtggctggc ctacaaggtg gcgtccaatg gcattcagta caccgacaga aggtggtgtt 6300 ttgatgggcc gcgcacgaat gccatactgg aggacaacac cgaggtagag atagtcaccc 6360 ggatgggtga gaggaaaatc ctcaagccga gatggcttga tgcaagagtt tatgcagatc 6420 accaagccct caagtggttc aaagactttg cagcagggaa gagatcagcc attagcttca 6480 tagaggtgct cggtcgcatg cctgagcatt tcatgggaaa gacgcgggaa gctttagaca 6540 ccatgtactt ggttgcaacg gctgagaaag gcgggaaagc acaccgaatg gctctcgaag 6600 agctgccaga tgcactggaa accatcacac ttattgttgc cattactgtg atgacaggag 6660 gattcttcct actaatgatg cagcgaaagg gtatagggaa gatgggtctt ggagctctgg 6720 tgctcacgct agctaccttc ttcctgtggg cggcagaggt tcctggaact aaaatagcag 6780 ggaccctgct gatcgccctg ctgctgatgg tggtgctcat cccagaaccg gaaaaacaga 6840 ggtcacagac agataaccaa ctggcggtgt ttctcatctg cgtcttgacc gtggttggag 6900 tggtggcagc aaacgagtac gggatgctag agaaaaccaa agcagatctc aagagcatgt 6960 ttgtcggaaa gacgcaggca tcagggctga ctggattgcc aagcatggca ctggacctgc 7020 gtccagccac agcctgggca ctgtatgggg ggagcacagt cgtgctaacc cctcttctga 7080 aacacctgat cacgtcggaa tacgtcacca catcgctagc ctcaattaac tcacaagctg 7140 gctcattatt cgtcttgcca cgaggcgtgc cttttaccga cctagacttg accgttggcc 7200 tcgtcttcct tggctgttgg ggtcaaatca cccttacaac gtttctgaca gccatggttc 7260 tggcgacact tcattatggg tacatgctcc ctggatggca agcagaagca ctcagggctg 7320 cccagagaag gacagcggct ggaataatga agaatgccgt tgttgacgga atggtcgcca 7380 ctgatgtgcc tgaactggaa aggaccaccc ctctgatgca aaagaaagtc ggacaggtgc 7440 tcctcatagg ggtaagcgta gcagcgttcc tcgtcaaccc taatgtcacc actgtgagag 7500 aagcaggggt attggtgacg gcggctacgc tcactttgtg ggacaatgga gccagtgccg 7560 tctggaattc caccacagcc acgggactct gccatgttat gcgaggtagc tacctggctg 7620 gaggttccat tgcttggact ctcatcaaga acgcggataa gccctccttg aaaaggggaa 7680 ggcccggggg caggacgcta ggggagcaat ggaaggaaaa actaaacgct atgagcagag 7740 aagagttttt taaataccga agagaggcca taatcgaggt ggaccgcact gaagcacgca 7800 gggctagacg tgaaaacaac atagtgggag gacatccggt ttcgcgaggc tcagcaaaac 7860 tccgttggct cgtggagaaa ggatttgtct cgccaatagg aaaagtcatt gatctagggt 7920 gtgggcgtgg aggatggagc tactacgcag caaccctgaa gaaggtccag gaagtcagag 7980 gatacacgaa aggtggggcg ggacatgaag aaccgatgct catgcagagc tatggccgga 8040 atctggtctc cttgaaaagt ggagtggacg tgttttacaa accttcagaa cccagtgaca 8100 ccctgttctg tgacataggg gaatcctctc caagtccaga agtagaagaa caacgcacac 8160 tacgcgtcct agagatgaca tctgactggt tgcaccgagg acctagagag ttctgcataa 8220 aagttctctg cccttacatg cccaaggtta tagaaaaaat ggaagttctg cagcgccgct 8280 tcggaggtgg gctagtgcgt ctccccctgt cccggaactc caatcacgag atgtattggg 8340 ttagtggagc cgctggcaat gtggtgcacg ctgtgaacat gaccagccag gtactactgg 8400 ggcgaatgga tcgcacagtg tggagagggc caaagtatga ggaagatgtc aacctaggga 8460 gcggaacaag agccgtggga aagggagaag tccatagcaa tcaggagaaa atcaagaaga 8520 gaatccagaa gctcaaagaa gaattcgcca caacgtggca caaagaccct gagcatccat 8580 accgcacttg gacataccat ggaagctatg aagtgaaggc tactggctca gccagctctc 8640 tcgtcaacgg agtggtgaag ctcatgagca aaccttggga cgccattgcc aacgtcacca 8700 ccatggccat gactgacacc accccttttg gacagcaaag agtcttcaag gagaaagttg 8760 acacgaaggc tcctgagcca ccagctggag ccaaggaagt gctcaacgag accaccaact 8820 ggctgtgggc ccacttgtca cgggaaaaaa gaccccgctt gtgcaccaag gaagaattta 8880 taaagaaagt caacagcaac gcggctcttg gagcagtgtt cgctgaacag aatcaatgga 8940 gcacggctcg tgaggctgtg gatgacccgc ggttctggga gatggttgat gaagagaggg 9000 aaaaccatct gcgaggagag tgtcatacat gtatctacaa catgatggga aaaagagaga 9060 agaagcctgg agagtttgga aaagctaaag gaagcagggc catttggttc atgtggcttg 9120 gagcacggta tctagagttt gaagctttgg ggttcctgaa tgaagaccat tggctgagcc 9180 gagagaattc aggaggtgga gtggaaggct caggcgtcca aaagctggga tacatcctcc 9240 gtgacatagc aggaaagcaa ggagggaaaa tgtacgctga tgacaccgcc ggatgggaca 9300 ctagaattac cagaactgat ttagaaaatg aagccaaggt gctggagctc ctagacggtg 9360 aacaccgcat gctcgctcga gccataattg aactgactta caggcacaaa gtggtcaagg 9420 tcatgagacc tgcagcagaa ggaaagaccg taatggacgt gatatcaaga gaagatcaaa 9480 gggggagtgg acaggtggtc acttatgccc ttaacacttt cacgaacatt gctgtccagc 9540 tcgtcaggct gatggaggct gagggggtca ttggaccaca acacttggaa cagctaccta 9600 gaaaaaccaa gatagctgtc aggacctggc tctttgagaa tggagaggag agagtgacca 9660 ggatggcgat cagcggagat gactgtgtcg tcaagccgct ggatgacaga ttcgccacag 9720 ccctccactt cctcaacgca atgtcaaagg tcagaaaaga catccaggaa tggaagcctt 9780 cgcatggctg gcacgactgg cagcaagttc ccttctgctc taaccatttt caggagattg 9840 tgatgaaaga tggaaggagc atagttgtcc cgtgcagagg acaggatgag ctgataggca 9900 gggctcgcat ctctccagga gctggatgga atgtgaagga cacagcttgt ctggccaaag 9960 catatgcaca gatgtggcta ctcctatact tccatcgtag ggacttgcgt ctcatggcaa 10020 atgcgatttg ctcagcagtg ccagtggatt gggtgcccac aggcaggacg tcctggtcaa 10080 tacactcgaa aggagagtgg atgaccacgg aagacatgct gcaggtctgg aacagagtct 10140 ggattgaaga aaatgaatgg atgatggaca agactccaat cacaagctgg acagacgttc 10200 cgtatgtggg aaagcgtgag gacatctggt gtggtagcct catcggaacg cgatccagag 10260 caacctgggc tgagaacatc tatgcggcga taaaccaggt cagagctgtc atagggaaag 10320 aaaattatgt tgactacatg acctcactca ggagatacga agacgtcctg atccaggaag 10380 acagggtcat ctagtgtgat ttaaagtaga aaagtagact atgtaaataa tgtaaatgag 10440 aaaatgcatg catatggagt caggccagca aaagctgcca ccggatactg ggtagacggt 10500 gctgtctgcg tctcagtccc aggaggactg ggttaacaaa tctgacaaca gaaagtgaga 10560 aagccctcag aaccgtctcg gaagtaggtc cctgctcact ggaagttgaa agaccaacgt 10620 caggccacaa atttgtgcca ccccgctagg gggtgcggcc tgcgcagccc caggaggact 10680 gggttaccaa agccgttgag cccccacggc ccaagcctcg tctaggatgc aatagacgag 10740 gtgtaaggac tagaggttag aggagacccc gtggaaacaa caatatgcgg cccaagcccc 10800 ctcgaagctg tagaggaggt ggaaggacta gaggttagag gagaccccgc atttgcatca 10860 aacagcatat tgacacctgg gaatagactg ggagatcttc tgctctatct caacatcagc 10920 tactaggcac agagcgccga agtatgtagc tggtggtgag gaagaacaca ggatct 10976 //