Dbfetch
ID JN116253; SV 3; linear; genomic RNA; STD; VRL; 12917 BP. XX AC JN116253; XX DT 05-DEC-2011 (Rel. 111, Created) DT 11-JAN-2017 (Rel. 131, Last updated, Version 6) XX DE Possum nidovirus isolate WPDV, complete genome. XX KW . XX OS Wobbly possum disease virus OC Viruses; Riboviria; Nidovirales; Arnidovirineae; Arteriviridae; OC Zealarterivirinae; Kappaarterivirus; Kappaarterivirus wobum. XX RN [1] RP 1-12917 RX DOI; 10.1016/j.vetmic.2011.11.013. RX PUBMED; 22153843. RA Dunowska M., Biggs P.J., Zheng T., Perrott M.R.; RT "Identification of a novel nidovirus associated with a neurological disease RT of the Australian brushtail possum (Trichosurus vulpecula)"; RL Vet. Microbiol. 156(3-4):418-424(2012). XX RN [2] RC Publication Status: Available-Online prior to print RP 1-12917 RX PUBMED; 28053107. RA Gulyaeva A., Dunowska M., Hoogendoorn E., Giles J., Samborskiy D., RA Gorbalenya A.E.; RT "Domain organization and evolution of the highly divergent 5' coding region RT of genomes of arteriviruses including the novel possum nidovirus"; RL J. Virol. 0:0(2017). XX RN [3] RP 1-12917 RA Dunowska M., Biggs P.J., Zheng T., Perrott M.R.F.; RT ; RL Submitted (13-JUN-2011) to the INSDC. RL Institute of Veterinary, Animal and Biomedical Sciences, Massey University, RL PO Box 11 222, Palmerston North, Manawatu 4442, New Zealand XX RN [4] RC Nucleotide and amino acid sequences updated by submitter RP 1-12917 RA Dunowska M., Biggs P.J., Zheng T., Perrott M.R.F.; RT ; RL Submitted (29-MAY-2013) to the INSDC. RL Institute of Veterinary, Animal and Biomedical Sciences, Massey University, RL PO Box 11 222, Palmerston North, Manawatu 4442, New Zealand XX RN [5] RC Sequence update by submitter RP 1-12917 RA Dunowska M., Biggs P.J., Zheng T., Perrott M.R.F.; RT ; RL Submitted (26-SEP-2016) to the INSDC. RL Institute of Veterinary, Animal and Biomedical Sciences, Massey University, RL PO Box 11 222, Palmerston North, Manawatu 4442, New Zealand XX DR MD5; be108bf16497f3a998ead1da64225a18. DR EuropePMC; PMC4505640; 25972539. DR EuropePMC; PMC5331827; 28053107. DR EuropePMC; PMC6057926; 30042503. XX CC On Jan 10, 2017 this sequence version replaced gi:507722022. XX FH Key Location/Qualifiers FH FT source 1..12917 FT /organism="Wobbly possum disease virus" FT /host="Trichosurus vulpecula (Australian brushtail possum)" FT /isolate="WPDV" FT /mol_type="genomic RNA" FT /country="New Zealand" FT /collection_date="1995" FT /db_xref="taxon:1118369" FT 5'UTR 1..245 FT CDS join(246..6218,6218..10453) FT /codon_start=1 FT /ribosomal_slippage FT /product="replicase polyprotein 1ab" FT /db_xref="GOA:G9FGR6" FT /db_xref="InterPro:IPR001205" FT /db_xref="InterPro:IPR008760" FT /db_xref="InterPro:IPR009003" FT /db_xref="InterPro:IPR023183" FT /db_xref="InterPro:IPR023338" FT /db_xref="InterPro:IPR027351" FT /db_xref="InterPro:IPR027355" FT /db_xref="InterPro:IPR027417" FT /db_xref="InterPro:IPR037227" FT /db_xref="UniProtKB/TrEMBL:G9FGR6" FT /protein_id="AEU12347.3" FT /translation="MSSAQGSTSYVNHIIAQYSWNLEQLDEISRLMLPSSRYAEMRVPG FT VVVRDATVSTVEIDLMGHKLTFGFKDMTPSEYKDFKMDETDGYCYRPFTGLDGGKHPST FT RFFNTFGGFDYCPSSPCWLSFTCDEGVIKYHFGKLQTGYLPLMPVVPGKKNNLLHCPVG FT LVGSAADALKKRYGISFPVANKNGPFSPDLTSTCNFVYHYDSMTQTMIPGDGAIVAYSP FT VPHEVCDYMELSYNREAEILNGSLGTNFNYVSGMPFIMASAVPVPGYKPVTMYVKDNMC FT VLNDGTAAPVIYVLNSSCNGYCYLKFRVPPVGPWPTLDECLGGDAGLTYGTDYSLIGAG FT NWVHITDYDKRTGVGISLAVGWNPAFAHLKKARVGGMIVDPQLGSTSGPKQCAVPEFGP FT QTAGGCASFVRQDIMTPTTGFVTIVDDHFATLKSNPPPDSFMASGVPPAIATNAASPFF FT EDIDVEADGWCGYSCLAKLNGFSGSTVKDSAIWVARFATLMKTELLDYIGRDLPADLWL FT TDDMIVKHTPYAVVTRDQMHCANVLGVMINNRGHWKCRLPTYRVAPETACSGLGCVHVE FT PRIERFPTIKYDWVFQNSARIESQVSEQDLLNEAFIGGKVITDQCLLSEITLTPRSSPP FT PQEPRKRKKRSKQKPVADPPAPKKLTDQVPEIKQPVASPVPAPRLHKPQPIKPVVPPVP FT APRTKKQRPVPAPRKLPDLVEKATPVAPAKARFAHVTNRTAAAVFEATVGWSNSLKAYV FT AKLPRTCPAWYSLSMFLLMALPPGLGSVLSFVLGAVFLFLTVSPVPLVISVTLFSWFVL FT TRPHFIQCSSWDRECLATNGLPMPESIVVMNRGSAGLIGLVIHLFAYAGMSRRIFATLR FT VVSVAVDTLALYAAYVLDGVLCFKCFHQCARTQKKLHSSEKAKNIVVNNTMILQFMDTY FT APPPVDLVKLATGVNGCHCGSKSFIQWSTARPVAYSRYDPTKSSAETVLPLPKNAEQAL FT RVISHALEHGVVVFHMGHTGVDVKRIEAYPASISPLPDFFPDLPYTSTEATLVVDVNLK FT AALSACGYPDMDKIVVGEGDWLLENEVYPIGVDQKRTCRYLSHHVSPGLWKNLSASDRA FT TLKDLNYRPTSFGFSVSLCRVFALVQIVAGLASYFVPVFDCGIGTYDKWCEVPFNSPVK FT GKHSLAVCSGATCVSPDGVFTRDPVFPVAICGLYISALAAAAIVISKLRISVGAIVTVI FT GSVLNYCFFPEYCYAGPLIFLAQLFMPWTIQSLATAALSAFLWDPTATIVVIILVATFM FT VWSSCGGSMASVNINGPVVSPLLLMSNGTAPSVVTPTTLACAAQSAGVPFASLVARAAV FT SRPGTVLKAAYDSAKDGKVRIYIPTGTGVVQEGAMRCNRVPSNVGVATGATTGTASGWS FT YGENSRIITATHVTGTPTFVTIGTQTFTIPQFNTNGDFAYVDINGNYGWPEYKTGQFEG FT PCFWLTRTGVETGAVVGKAAVAFTHPGDSGSPVVTKDNVILGVHSASNQRGLAVITDCS FT GVEIGYQPVQLSKMVKLFSGPLTRAPAVMPANIVRDIESVPETLANALNGQLNYEGGLP FT ILVEICVAVVMIMLAKEPVVVLSGCFIFLLSNMLPRMVARACYNVLLAWLSVTPGYHYA FT LALRCAEIGMAGNFGSALLYSLTTVAAVVLNGRLALYPVYGYTTVALVFAFNMLCVALH FT YYRVLTPLSDAVFVRCRFNVLRLVRHLMEGSPESIMPVTEAPVLPLSAVLTSTFSTEEL FT DFLAQHDHVFVKASNLAHNEALKRQAVVRRAINLWNSNVVPTKHRVRGLASLKDYTTVP FT VVEVGDTVHVLGGVIGLNACGPYDVEVTKITNFFGQDVGTGIVRAVKEGSGNPAVDRAM FT MLDEADRTIDRKLNDEQAMVGGKVVTLSPTGTHSRVDGKGFTTPVSAVEAAVARKLLVQ FT ESDTNTEVLDTTSGKYMKRVNAKGDVFYELIEEGLQEKDVAKLRKAIQRLQALLPDLNR FT ARGTSNISPEVPLGFVDGRDITIVPRSRTFICGAFNIKVLPTKEEINNTPAGSYDLVEG FT CMIRPHYPSLIDKLLAAIHGSCYVTPTVPVILKNPGDTDGCGHEWDFEELTVPRSRVFA FT QDIATALRNEAGLMTIGYPYRMTPMNPAGSNRRYVPTLKGEGAFVGGYYPAVGVSFPMH FT AFGLSARSSIDGELTIDANGTILGIAPRLKSTEKLPTVPSSIAREFSEVTAYLPRVDAK FT NCLADLLKYRYNNYGRVFPSVLQIVRKYMLRYAAGPIYKASDIPSKDSHAGLAATRGLT FT TKALQALPDIDHKVYMFNLDSNASVTPVSPKIQYIGKVKVRTILGTCAIPALWLRASMS FT GVLAKLKPEPPLMLGENKFLPIPKLRRYRASVDVVSCDRTTPACIRDFCASLFDEMCGA FT PDFYINYHRHCVSEFIAFDGKIFVKPGGLSSGDPVTTLSNCVYSLSIYVQHVILSALRL FT NYRPIAEKYLEEELTVEDCMDWVPALIYGDDVVLHTDCVTGRESFKLWREHFIFFSGVY FT TREEAVEAETPEFLGCSVVTDDDKSRLVPQRERVLRALAFNLSATDVDTYYQRAEAILL FT DASAASDQEWFSSILDRVWMCAYVDGVDFPSLSFFQDFYKRVSSEAIFSCSICRGNAIA FT FCTCGFKLCVKHINIHYYPPEHDPRLPCGHRLSQRNGRFDCIGCGGVSNDRWSPVEPAN FT PNLCEVLGIWLATEYTHSQRVSRAVEAVFDGATWEPQLPPGRYVTGNTRFAVLRSCAGF FT ETVPVLSCGTHVVRSVCIDLHGIRLQEVVEHLAASSYTCGPPGSGKSRLLSAKAQERQS FT TIVTPSHVCCDEYIRNLDCQYVNSKFYQYSKPSNPNARIHVALASSSPTAYGALLVDEV FT FMIHPSDLFRWVTMRPIFCVGDHNQLAAITHSAMPVKLHTLFGKTSVLDTIHRFSGPLV FT DVISHLYSTKLTGAGPNCEIKFASTQPPGSLQITPYHRDRAPDGKTVDSCQGSTHDHIY FT LHVPRRFSLNKNRALVALTRARYSITINDPHNELSRVGFNIPRSEGQTVPLPLPAVCHN FT AGFYYSDVPGYLLPLPVELRDLWPIVTTGPVTHNCLSISITERPGYHPAICAGYVVGDD FT TFKGEPNVASYYYAIFRDGVNVTPRSIFSSGRLLLNDRTAYPGEQEAMDTWPHVFKGDI FT KGHTIGGCHHVTSPNLPQDLAPAMFRAVGSSLPGKAAKACTSVFDCYAPYLVDIANTVT FT GKSQVVKVTYDLAEKRLMVWKGATFYFQGVCYRVLKELAGQILLPSDLPLCLATCDDIE FT TSGPVTTVCKPEAVHMFHYAKSGYSVVSVPITQPLPKCIAARARFTASGPVCYVFLDNT FT GALNETCSIGEDLRRPCAPCMPSCSFAPRRIRLTHPISTSTPISPAALKFFNS" FT CDS 246..6242 FT /codon_start=1 FT /product="replicase polyprotein 1a" FT /db_xref="GOA:G9FGR7" FT /db_xref="InterPro:IPR008760" FT /db_xref="InterPro:IPR009003" FT /db_xref="InterPro:IPR023183" FT /db_xref="InterPro:IPR023338" FT /db_xref="UniProtKB/TrEMBL:G9FGR7" FT /protein_id="AEU12356.3" FT /translation="MSSAQGSTSYVNHIIAQYSWNLEQLDEISRLMLPSSRYAEMRVPG FT VVVRDATVSTVEIDLMGHKLTFGFKDMTPSEYKDFKMDETDGYCYRPFTGLDGGKHPST FT RFFNTFGGFDYCPSSPCWLSFTCDEGVIKYHFGKLQTGYLPLMPVVPGKKNNLLHCPVG FT LVGSAADALKKRYGISFPVANKNGPFSPDLTSTCNFVYHYDSMTQTMIPGDGAIVAYSP FT VPHEVCDYMELSYNREAEILNGSLGTNFNYVSGMPFIMASAVPVPGYKPVTMYVKDNMC FT VLNDGTAAPVIYVLNSSCNGYCYLKFRVPPVGPWPTLDECLGGDAGLTYGTDYSLIGAG FT NWVHITDYDKRTGVGISLAVGWNPAFAHLKKARVGGMIVDPQLGSTSGPKQCAVPEFGP FT QTAGGCASFVRQDIMTPTTGFVTIVDDHFATLKSNPPPDSFMASGVPPAIATNAASPFF FT EDIDVEADGWCGYSCLAKLNGFSGSTVKDSAIWVARFATLMKTELLDYIGRDLPADLWL FT TDDMIVKHTPYAVVTRDQMHCANVLGVMINNRGHWKCRLPTYRVAPETACSGLGCVHVE FT PRIERFPTIKYDWVFQNSARIESQVSEQDLLNEAFIGGKVITDQCLLSEITLTPRSSPP FT PQEPRKRKKRSKQKPVADPPAPKKLTDQVPEIKQPVASPVPAPRLHKPQPIKPVVPPVP FT APRTKKQRPVPAPRKLPDLVEKATPVAPAKARFAHVTNRTAAAVFEATVGWSNSLKAYV FT AKLPRTCPAWYSLSMFLLMALPPGLGSVLSFVLGAVFLFLTVSPVPLVISVTLFSWFVL FT TRPHFIQCSSWDRECLATNGLPMPESIVVMNRGSAGLIGLVIHLFAYAGMSRRIFATLR FT VVSVAVDTLALYAAYVLDGVLCFKCFHQCARTQKKLHSSEKAKNIVVNNTMILQFMDTY FT APPPVDLVKLATGVNGCHCGSKSFIQWSTARPVAYSRYDPTKSSAETVLPLPKNAEQAL FT RVISHALEHGVVVFHMGHTGVDVKRIEAYPASISPLPDFFPDLPYTSTEATLVVDVNLK FT AALSACGYPDMDKIVVGEGDWLLENEVYPIGVDQKRTCRYLSHHVSPGLWKNLSASDRA FT TLKDLNYRPTSFGFSVSLCRVFALVQIVAGLASYFVPVFDCGIGTYDKWCEVPFNSPVK FT GKHSLAVCSGATCVSPDGVFTRDPVFPVAICGLYISALAAAAIVISKLRISVGAIVTVI FT GSVLNYCFFPEYCYAGPLIFLAQLFMPWTIQSLATAALSAFLWDPTATIVVIILVATFM FT VWSSCGGSMASVNINGPVVSPLLLMSNGTAPSVVTPTTLACAAQSAGVPFASLVARAAV FT SRPGTVLKAAYDSAKDGKVRIYIPTGTGVVQEGAMRCNRVPSNVGVATGATTGTASGWS FT YGENSRIITATHVTGTPTFVTIGTQTFTIPQFNTNGDFAYVDINGNYGWPEYKTGQFEG FT PCFWLTRTGVETGAVVGKAAVAFTHPGDSGSPVVTKDNVILGVHSASNQRGLAVITDCS FT GVEIGYQPVQLSKMVKLFSGPLTRAPAVMPANIVRDIESVPETLANALNGQLNYEGGLP FT ILVEICVAVVMIMLAKEPVVVLSGCFIFLLSNMLPRMVARACYNVLLAWLSVTPGYHYA FT LALRCAEIGMAGNFGSALLYSLTTVAAVVLNGRLALYPVYGYTTVALVFAFNMLCVALH FT YYRVLTPLSDAVFVRCRFNVLRLVRHLMEGSPESIMPVTEAPVLPLSAVLTSTFSTEEL FT DFLAQHDHVFVKASNLAHNEALKRQAVVRRAINLWNSNVVPTKHRVRGLASLKDYTTVP FT VVEVGDTVHVLGGVIGLNACGPYDVEVTKITNFFGQDVGTGIVRAVKEGSGNPAVDRAM FT MLDEADRTIDRKLNDEQAMVGGKVVTLSPTGTHSRVDGKGFTTPVSAVEAAVARKLLVQ FT ESDTNTEVLDTTSGKYMKRVNAKGDVFYELIEEGLQEKDVAKLRKAIQRLQALLPDLNE FT QGVPQI" FT misc_feature 6212..6218 FT /note="ribosomal slippage site" FT CDS 10309..10932 FT /codon_start=1 FT /product="glycoprotein 2" FT /note="GP2" FT /db_xref="GOA:G9FGR8" FT /db_xref="UniProtKB/TrEMBL:G9FGR8" FT /protein_id="AEU12348.1" FT /translation="MLNWRRFATALCTLYAFLLVRTAADTPDPSYQYVHAHISSCAKIF FT QQLDIDFNQSLPVMLADLIEQPSHWLSTHPGVVRAFDEIHDTYTLATSYYELPHSYILH FT EMLGNAEAVLEPLRYYRTHFRYLDRMALESLAHLSYIKVQQDNDTLANATFTIHPNIQW FT NELQFAGVVPSPFYMVYMSMACWLITIHAFLRLRFQWILCATSR" FT CDS 10553..10690 FT /codon_start=1 FT /product="envelope protein" FT /note="E" FT /db_xref="GOA:G9FGR9" FT /db_xref="UniProtKB/TrEMBL:G9FGR9" FT /protein_id="AEU12349.1" FT /translation="MRYMTPTHLPPVTMSSLTVTSCMKCWGMRRPSWSHSGIIAHTLDT FT " FT CDS 10794..11447 FT /codon_start=1 FT /product="glycoprotein 3" FT /note="GP3" FT /db_xref="GOA:G9FGS0" FT /db_xref="UniProtKB/TrEMBL:G9FGS0" FT /protein_id="AEU12350.1" FT /translation="MERIAVRWGCALAFLYGLYVNGVLADNNTCLSATTISVDTLCNVT FT LNYPAFVMTAPHEDLVYQYMAHQYVNVSKLNYTSGNPCLVDAYHTARTLALQNDTVHVS FT FSGHSFIIFKHNCTFLSNTSVCIRGVEHQVGYSGNITLYKSTGIVCKHNHTRYTDFFIS FT IANSTYVPGIKGYLVICGFYMPMVSLFALGLSGTLAVYTELRLLLNGVLTSSRS" FT CDS 11330..11581 FT /codon_start=1 FT /product="glycoprotein 4" FT /note="GP4" FT /db_xref="UniProtKB/TrEMBL:G9FGS1" FT /protein_id="AEU12351.1" FT /translation="MRLLYAYGVFVCLGFIWHFSCVHGTPITFKWCSNVVPELNCSVYG FT PFDRHLLHTETYYAPVYWVTGYPVSSLTHFSLVERPQS" FT CDS 11578..12114 FT /codon_start=1 FT /product="glycoprotein 5" FT /note="GP5" FT /db_xref="GOA:G9FGS2" FT /db_xref="UniProtKB/TrEMBL:G9FGS2" FT /protein_id="AEU12352.1" FT /translation="MKALIDLTYANLTMELGHQINVREENGTYAQAAALLFASIASMPH FT FTLGSHPVKRVSVLYHHNKTDHCFGVRLHIATHFCNQTKLEVNCINDYLHTCQIPLCAH FT GNLLCVPTHVRCNPWFARTSFFDMYLRSLALSDKQRYHKYLDYHAHLSFAAPITCLILT FT TYVIFTLMARVRISG" FT CDS 11603..11839 FT /codon_start=1 FT /product="glycoprotein 5a" FT /note="GP5a" FT /db_xref="UniProtKB/TrEMBL:G9FGS3" FT /protein_id="AEU12353.1" FT /translation="MQTSPWSLDTKLMLGRKMVLMLKLLRSSSHRLHPCHTSHWDLTPS FT RGCRCCIIITRLTIASACAYTSPRIFATRRSLR" FT CDS 12051..12593 FT /codon_start=1 FT /product="membrane protein" FT /note="M" FT /db_xref="GOA:G9FGS4" FT /db_xref="UniProtKB/TrEMBL:G9FGS4" FT /protein_id="AEU12354.1" FT /translation="MSDSYNICHIYANGTSADFWLGYAFDTIIVAQPMLLVLAGLITWK FT MFRLIVTPVLTLLTLYLLGFEVYITIKSGLQRSQGVIALCLAIFTLTGVLLLYVRNFCL FT TFRHVGLRAACTGITYLLHKDGSTSKVASEWPILVETHGTQRTANGTHWPPTSKLYHAG FT TEIRGDTGQAIRISKLR" FT CDS 12424..12804 FT /codon_start=1 FT /product="nucleocapsid protein" FT /note="N" FT /db_xref="GOA:G9FGS5" FT /db_xref="UniProtKB/TrEMBL:G9FGS5" FT /protein_id="AEU12355.1" FT /translation="MAARRRSRQNGRSSSRPMARNAPPTGRTGRQRRNYITPEQRSAVT FT LARQYGSASSASPVAGITGLLKPHYSPDATLVTGDAREIGPAACRLIARAALALAQGHG FT EIIANDEAFVFALTLPRKGRNA" FT 3'UTR 12805..12901 FT polyA_site 12902 XX SQ Sequence 12917 BP; 3063 A; 3390 C; 3102 G; 3361 T; 1 other; cggctgtgag tgcttagcat atgctagagt actacagccg ggtgttggag tcatatgcac 60 tggttgcctg tataatagtc gggatctgtc tgacctacat tatctttggg agttgcttat 120 cacgacaatt ctcgaagtgt ctgtcgacag cttacccccg attcgacaag gccccttgtc 180 caccgcagac ctatcgattt tcaacgagaa cactatcaga ggtttaaatt taaaactcac 240 caacaatgtc atcggcccag ggttcaacct cgtacgtcaa ccacattatt gcacagtaca 300 gttggaacct cgaacaatta gacgaaattt cccggttgat gttaccttct agccgctacg 360 ctgaaatgag ggtccctgga gttgtagtac gtgatgctac agttagcacc gtggaaattg 420 acttaatggg ccacaaattg acctttggat ttaaggacat gactccctct gagtacaaag 480 acttcaaaat ggatgaaact gacggttatt gctaccgtcc ttttaccgga cttgacggcg 540 gaaaacatcc gtccacccga tttttcaata cttttggcgg cttcgattac tgtcctagct 600 ccccttgctg gttgagcttc acatgtgacg aaggcgtcat aaaataccac tttggaaagt 660 tgcagacagg ataccttcct ttgatgcccg tcgtgcctgg caagaagaac aacttgctcc 720 actgcccagt tgggctcgtt ggttcggccg ccgacgcatt aaagaagcgg tacggaatct 780 cctttccagt ggctaataag aatggacctt tttcaccgga cttgacctct acctgtaact 840 tcgtgtacca ttatgacagt atgactcaga ccatgatacc cggagacggg gcgatcgtgg 900 cttacagtcc tgtccctcac gaggtttgtg actacatgga actatcctac aaccgtgaag 960 ctgaaatcct aaacggtagc ttgggaacca atttcaacta tgtgtcaggg atgccgttca 1020 tcatggcgtc cgccgtaccc gtgcctggtt acaaaccggt caccatgtac gtcaaggaca 1080 acatgtgcgt actcaacgac ggtactgcag cgcctgtcat ttacgtgctt aacagctcgt 1140 gcaatgggta ctgctacctg aagttcagag ttccgccagt tggtccttgg cccacattgg 1200 atgagtgttt gggcggagac gctggattga catacggcac tgattattcg ttgattggag 1260 caggcaactg ggtccacatt accgactatg acaaacgcac tggagtgggt atctcacttg 1320 ctgtaggttg gaatcccgcc ttcgctcacc ttaaaaaagc tcgcgtaggt ggtatgatag 1380 ttgacccgca attgggatcc acttccggac cgaaacagtg tgccgtgcct gagtttggac 1440 cacaaaccgc tggcggctgt gctagttttg tgagacaaga cattatgact cccaccaccg 1500 gatttgtcac tatcgttgat gaccactttg caactctgaa gtcaaacccc ccaccggact 1560 ccttcatggc ctccggggtg ccgcccgcaa tagctacgaa tgcggcgtcg ccattcttcg 1620 aggacattga cgttgaggct gatggctggt gcggctacag ctgtttagca aagttaaatg 1680 gattcagcgg tagcacagtt aaggacagcg ccatctgggt tgctcgtttt gcgactctga 1740 tgaagaccga attactggat tacattgggc gagatctgcc cgctgacctg tggctgactg 1800 atgatatgat tgttaaacac accccttacg ccgtggtcac tagagaccag atgcattgtg 1860 ctaacgtgct tggcgtcatg atcaacaatc gtggccattg gaagtgtcgg ttgcccactt 1920 atcgagttgc gccagaaact gcctgttctg gccttggatg tgttcatgtt gagccacgta 1980 ttgaaagatt ccccacgatc aaatacgatt gggtgttcca gaattcagcc cgcatcgaga 2040 gccaggtgtc tgagcaagac ttgctcaacg aggctttcat tggtggtaaa gtcattacgg 2100 atcagtgctt gcttagtgag atcactctaa cccccagatc atctccaccc ccgcaagagc 2160 cgcggaagcg caaaaagcgc agcaagcaga aacccgtagc tgatccccct gctcccaaaa 2220 agttgaccga tcaagtccct gaaatcaagc agcctgtggc gtcaccagtt ccagcaccac 2280 ggctccacaa accccaacca ataaaaccag ttgtgccacc tgtgccagcc ccgcgtacga 2340 agaagcagcg gccagtcccg gcccctcgca aactccccga cttggttgag aaggctaccc 2400 cagtcgctcc tgctaaggca cgttttgcgc atgttaccaa ccgcactgcc gcagcagttt 2460 ttgaagcaac cgtgggctgg tccaactccc ttaaagcgta cgtggctaaa ctaccgcgca 2520 catgccctgc ctggtacagt ttgtcaatgt ttctattgat ggccttgccc ccaggccttg 2580 gcagtgtgct tagttttgtg cttggtgcag tgttcctgtt ccttacagtg tcaccagtgc 2640 ccctggttat ttcagtaaca ctcttctcct ggtttgtcct cactcgcccc cactttatac 2700 agtgttcatc ctgggaccgc gagtgcctcg cgactaacgg tttacctatg cccgagtcga 2760 tcgtagttat gaaccgtggg tctgccggtc tgattgggct tgtgatacac ctgtttgctt 2820 atgccggtat gtcgcgcagg atatttgcta ctctcagagt tgtgtcagtt gcagttgata 2880 ccttagcatt gtatgcagct tatgtccttg atggggtttt gtgtttcaaa tgtttccatc 2940 agtgcgctcg cactcaaaag aagctgcact ccagtgagaa ggccaaaaat attgtagtga 3000 acaacaccat gattttacag tttatggaca cctacgcgcc acctccagtt gacctggtca 3060 aactcgccac cggcgtgaac ggttgccact gtggtagtaa gagcttcatc cagtggagca 3120 ctgctcgccc ggtagcatac agcaggtacg atcccacaaa atcctcagcg gagaccgtgc 3180 taccactacc taagaatgct gagcaggcat tgcgagtgat cagccacgcc cttgagcatg 3240 gtgtcgtagt gttccatatg ggacacactg gtgttgatgt caaacggatt gaggcatacc 3300 ctgcatctat ctctccgttg cccgatttct tcccagatct gccctacacc tcgactgaag 3360 caacactcgt cgtggatgtc aaccttaagg cggcgctctc tgcctgtggt tatcccgaca 3420 tggacaagat cgtagtcggt gagggtgatt ggctgttgga aaacgaggtt tacccgattg 3480 gagtggatca gaaaagaact tgcagatatc tgtcccacca cgtatcacct ggattgtgga 3540 aaaacctgtc agcgagtgac cgagctacgc tcaaggacct gaactaccgc ccaacatctt 3600 tcggtttttc agttagtctt tgccgcgtgt tcgccctggt gcagattgtt gctggcctcg 3660 catcatattt cgtgccggtc ttcgattgtg gtatcggtac atacgataaa tggtgtgagg 3720 tacctttcaa ctcccccgtg aaaggcaaac acagccttgc agtctgttct ggtgcaacat 3780 gtgtttcacc cgatggtgtt ttcacccgag atccagtgtt cccagtggca atatgcggct 3840 tgtacatctc agctctcgca gctgccgcga ttgttatctc caaattgaga atatctgtag 3900 gtgcaattgt gaccgtcatt ggctcagtac tcaactattg cttcttccca gagtattgtt 3960 atgcagggcc actaattttt cttgctcagc tattcatgcc ttggaccata caatcattag 4020 ccaccgcagc gctgtcggcg tttttatggg atcccacagc tactattgtt gtaatcatat 4080 tggttgccac attcatggtg tggtcttcct gcggtggttc aatggcttca gtgaacatca 4140 atggcccggt agtgtcgcct ctactactca tgtccaatgg tactgctccc tctgtggtca 4200 cgcccacaac cctggcatgt gccgcacagt ctgctggagt ccctttcgcc agcctggtcg 4260 cgcgagcagc cgtcagtcgg ccgggtactg tgcttaaagc ggcatatgac tctgctaaag 4320 atggcaaggt cagaatctac attcccacgg ggactggcgt cgtacaagag ggtgcgatgc 4380 ggtgtaaccg agtgccgtca aatgtcggcg tcgccactgg cgccacgaca ggcaccgcat 4440 ccggatggtc atatggagag aactcaagaa tcattacagc cactcatgta accggcacac 4500 cgacgttcgt gaccattggc acccaaacat tcaccatccc tcagtttaac accaacgggg 4560 atttcgctta tgtggacatc aatgggaatt acgggtggcc ggaatacaaa accggccagt 4620 ttgagggacc ttgtttttgg ttaacacgaa ccggtgttga aacaggtgcg gtagttggaa 4680 aggcagcagt cgctttcacc caccctggtg atagcggctc cccagttgtg acgaaggaca 4740 atgttatact cggagtgcac tccgccagta accagcgcgg attagctgtc atcaccgatt 4800 gttcaggcgt cgaaattggg taccaacctg tccagctatc gaaaatggtt aagttgttct 4860 ctggacctct gacacgcgca cctgcagtca tgcccgcgaa catcgtccgg gacattgagt 4920 ctgttccaga gaccttagcc aatgcattga acggccaact gaactatgag ggtggtttac 4980 ctatcttggt ggaaatctgt gttgcagtcg tcatgatcat gttagccaag gaaccagttg 5040 tggtgttgtc aggatgcttc atcttcctgc ttagtaatat gctaccgcgc atggttgcaa 5100 gagcctgtta caacgtgctc ctggcttggc tgtcagttac ccccggttac cactacgcgc 5160 ttgcactccg ctgcgctgag attggtatgg ctggtaactt tggatctgcc ctgctctatt 5220 cactgacgac tgtggccgct gttgtgctga atggccgttt agcattatat ccagtctatg 5280 gctacaccac tgtcgccctt gtctttgcat tcaacatgtt atgtgttgcc cttcattact 5340 acagagtgtt gacgccgtta tctgatgccg tttttgtgcg gtgccggttt aacgtgctaa 5400 ggctagttag acatttgatg gaaggctccc cggagagcat tatgcctgtg acagaagcgc 5460 ctgtgctacc acttagcgcg gtgctgactt ccaccttttc cacagaggag cttgactttc 5520 ttgcccaaca tgaccatgtt ttcgtcaaag catccaacct ggcccacaac gaggctctca 5580 agcggcaggc cgttgtccgg cgtgccataa acttatggaa ttccaacgtt gtacctacca 5640 aacatcgtgt ccgcggcttg gcgtctctca aagattacac cacagttccg gtagttgaag 5700 ttggtgacac cgtgcatgtc ctcggtggag ttattggctt gaatgcctgc ggaccatatg 5760 acgttgaagt gaccaagata actaacttct ttggtcagga tgttggtacc ggcatcgtca 5820 gagctgtcaa ggagggtagc ggcaacccag cagttgaccg tgccatgatg ctcgacgagg 5880 cagacaggac cattgacaga aagctgaatg atgagcaagc aatggttggt ggcaaggttg 5940 ttacccttag ccccaccggg acacattctc gtgttgatgg caaaggattc accactcctg 6000 tttctgctgt tgaagctgcc gttgcaagaa agctacttgt ccaagaaagt gacaccaaca 6060 ccgaggttct tgacactacc tcaggtaagt acatgaagag ggtcaatgcc aaaggggacg 6120 tcttttatga gttgattgaa gaaggcctgc aggaaaaaga cgtagctaag ctgagaaaag 6180 cgatccaaag actccaggct ctcctaccag atttaaacga gcaaggggta cctcaaatat 6240 aagcccagag gtccccctag ggtttgtcga tgggcgtgat atcacgatag tacctcgcag 6300 ccgcactttc atttgcggtg cgttcaacat caaggtgctg cccactaagg aagagatcaa 6360 caacacccca gctggttctt atgaccttgt tgaaggatgc atgattagac cacactaccc 6420 cagcttaatt gacaaactgc tggcagcaat ccacggttcc tgctacgtga cacctaccgt 6480 accggtgatc ctgaaaaacc ctggtgatac cgacggttgt ggccatgagt gggacttcga 6540 ggagttgact gttcccagaa gcagggtgtt tgcacaagac attgctaccg ccttacgtaa 6600 cgaagctggt cttatgacaa ttggctatcc ctatcgtatg acacccatga acccagccgg 6660 ctcaaacaga cgttacgtgc ccactttgaa aggcgaaggt gctttcgtag gtggttatta 6720 cccagctgtt ggagtatctt tccccatgca cgcctttgga ctgtccgcac gcagcagcat 6780 cgatggcgaa ctcactattg acgccaatgg aaccattctg ggtatcgccc caaggttgaa 6840 atctactgag aagctgccaa cagtcccatc gtctatcgct agagagttta gtgaggtcac 6900 cgcttactta cctcgcgtag acgctaagaa ctgcttggca gaccttctga agtatcgata 6960 taacaactat gggcgtgtct tccccagtgt tctccaaatt gtgcgcaagt acatgttgag 7020 atatgccgcc ggccctatat ataaggcctc agacatcccg agcaaagact cgcatgccgg 7080 ccttgctgca acgcgtgggt tgactaccaa agcgcttcaa gcattacctg acattgacca 7140 caaagtttat atgttcaatc tcgactctaa cgcctctgtc acaccagtgt cacctaaaat 7200 tcagtatatc gggaaagtca aagtgagaac catacttgga acatgtgcca tcccagcgtt 7260 gtggctccga gcgtcaatga gtggagtcct cgcgaagttg aagcccgagc ccccattgat 7320 gcttggtgag aacaagtttc tcccgatacc caaattgcgg cgttaccgag caagtgttga 7380 tgttgtgagt tgtgaccgta ccacaccagc ctgcattcga gatttctgtg cttcactatt 7440 tgatgaaatg tgtggagccc cagactttta catcaactat caccgccact gtgtttccga 7500 gtttatagct tttgatggga aaatctttgt gaagcctggc ggtttgtcat caggagaccc 7560 agttaccacc ctctccaatt gtgtgtatag ccttagcatc tatgtgcaac acgtaatcct 7620 cagcgcattg agattaaact atcgaccgat agctgagaaa tacttggagg aggagttgac 7680 agtggaagat tgtatggact gggtcccagc actaatttat ggtgatgacg tggtactaca 7740 cactgattgt gtaactggcc gtgagagctt caaactttgg agagagcatt tcattttctt 7800 ttctggtgtt tatacgcgag aagaggcggt tgaagctgaa acacctgagt ttcttggttg 7860 tagtgttgtt actgatgatg acaagtcacg ccttgtacca cagcgtgaac gcgtgttgcg 7920 agctcttgca tttaatttga gcgcgaccga cgttgacacc tactaccaga gagctgaggc 7980 aattttactt gatgcctctg ctgccagtga tcaagaatgg ttttcctcta ttctggatag 8040 agtttggatg tgtgcttatg ttgatggtgt ggactttcct tcattgtcgt tctttcagga 8100 tttttacaag cgggtgtcga gcgaggctat ctttagctgc tctatttgtc gcggtaacgc 8160 gatcgctttc tgcacctgcg gttttaagtt gtgtgtcaaa cacataaaca tacactatta 8220 tcctcctgaa cacgacccaa gactgccctg tggtcaccgt ctaagtcagc gcaatggtcg 8280 ttttgattgc attggctgcg gcggcgtcag caatgatcgc tggtctccgg ttgaaccagc 8340 aaacccaaac ctttgcgagg tccttggaat ctggcttgcc accgaataca cacattccca 8400 acgtgtgtcg cgagctgtgg aagcagtctt tgatggcgct acatgggaac cccagcttcc 8460 gcccggtcga tatgtcacag gcaacacccg gtttgcggta ttgcgttcat gcgcaggttt 8520 tgaaacagtt cccgtactat catgtgggac acatgtggtt cgcagtgtgt gcatcgactt 8580 acatggaatc cgacttcagg aagttgttga gcaccttgcg gcctcatctt acacttgcgg 8640 cccacctgga tctggaaagt cccgactgtt gtctgccaag gcacaggaac gccagtctac 8700 catcgtcacc cccagccacg tctgttgcga cgagtacatc cgcaacctcg actgtcaata 8760 cgtcaacagc aaattctacc agtayagcaa gcccagtaac ccaaacgccc gcatccacgt 8820 cgcactcgcc agtagcagcc ctacagccta tggggcgctg ctggtcgacg aggtttttat 8880 gatacaccct agtgacctgt ttcggtgggt tactatgcga ccaatctttt gcgttggcga 8940 tcataaccag cttgctgcga taactcattc tgctatgccg gtcaagttgc atactctatt 9000 tgggaaaacc agtgttttag acacgattca ccgcttcagc ggtccgctgg ttgacgtaat 9060 ttcacatttg tacagcacaa aattgaccgg tgctgggcca aactgcgaga tcaaattcgc 9120 gagcacacag ccaccgggaa gcttgcagat cactccatac cacagagacc gcgccccgga 9180 tggaaaaaca gttgatagtt gtcaaggtag cactcatgat cacatctacc tgcatgtgcc 9240 tagaaggttc agcctaaaca aaaacagagc acttgttgca cttaccaggg ccaggtattc 9300 tattaccatc aatgatccgc ataacgagct gtcgagagtt ggcttcaaca ttccgcgctc 9360 tgaggggcag accgtaccgt taccacttcc agctgtgtgt cacaatgctg ggttttatta 9420 cagtgatgtt ccaggctatt tattgccttt accagttgag cttagagatc tgtggccaat 9480 cgtcacaacc ggaccagtca cccacaactg cctgtccatc tcaatcactg aaagacctgg 9540 ttaccatcct gctatctgtg ctggttacgt ggtcggtgat gacactttca aaggagaacc 9600 caacgtggcg tcgtactact atgcaatctt cagagacgga gtcaacgtca ctcctcggtc 9660 catcttctca tccgggcggc tactgttaaa tgaccgaaca gcataccccg gagaacagga 9720 ggccatggac acttggcctc atgttttcaa gggcgatatc aaaggccaca ccataggtgg 9780 ttgtcatcac gtaaccagcc ccaacctgcc ccaagaccta gctccggcca tgtttagagc 9840 cgttggatca tccttacctg ggaaagccgc caaggcttgc acatctgttt ttgactgtta 9900 cgcgccctat ctagtggata tagcaaatac tgtgaccggt aagagccagg tcgtgaaggt 9960 tacttatgat ttggctgaga agagactaat ggtctggaaa ggtgccacct tttacttcca 10020 gggggtgtgt taccgcgtct tgaaagagct tgcgggccag attctgttgc ctagcgacct 10080 cccgttgtgt ctcgccacat gtgatgatat tgaaaccagc ggcccagtga ccaccgtatg 10140 caaacctgag gccgtccaca tgttccacta cgccaaatcg ggctacagcg tggtgtcagt 10200 tccaataact cagccattac ccaaatgcat tgctgcgagg gccagattca cagctagcgg 10260 ccctgtgtgc tatgttttcc tggacaacac tggtgcactg aatgaaacat gctcaattgg 10320 cgaagatttg cgacggcctt gtgcaccttg tatgccttcc tgctcgttcg caccgcggcg 10380 gatacgcctg acccatccta tcagtacgtc cacgcccata tctccagctg cgctaaaatt 10440 tttcaacagc tagacatcga cttcaatcag tcgctacctg tgatgcttgc tgatttaatt 10500 gagcaaccgt cgcactggtt aagtacacac ccgggagtgg tgcgagcttt tgatgagata 10560 catgacacct acacacttgc caccagttac tatgagctcc ctcacagtta catcttgcat 10620 gaaatgttgg ggaatgcgga ggccgtcctg gagccactca ggtattatcg cacacacttt 10680 agatacctag atcgtatggc gcttgagagc ctcgcacatc tatcttacat caaagttcaa 10740 caggacaatg acacgcttgc aaatgccacc ttcacgatcc acccaaatat acaatggaac 10800 gaattgcagt tcgctggggt tgtgccctcg cctttttata tggtctatat gtcaatggcg 10860 tgctggctga taacaataca tgcctttctg cgactacgat ttcagtggat actttgtgca 10920 acgtcacgct gaattaccca gctttcgtca tgacagctcc tcatgaagat ctggtgtatc 10980 agtatatggc tcaccaatat gtcaatgtgt ccaaactgaa ttacacgtca gggaaccctt 11040 gcctcgtaga cgcttatcac actgccagga cgcttgccct acaaaatgac acggtgcacg 11100 ttagcttctc aggtcacagt ttcatcattt tcaagcataa ctgcactttt ctgtctaaca 11160 cttcagtgtg catcagggga gtggaacacc aggtaggata ctcaggtaat atcacattgt 11220 acaagtccac aggcattgtg tgcaaacata accatacaag atacacggac tttttcattt 11280 ccatagctaa ttcaacatat gtgcccggca taaaaggtta tcttgtgata tgcggcttct 11340 atatgcctat ggtgtctttg tttgccttgg gtttatctgg cactttagct gtgtacacgg 11400 aactccgatt acttttaaat ggtgttctaa cgtcgtcccg gagttgaact gttccgtgta 11460 cggtcccttt gaccgacatc tgcttcacac tgagacctac tatgctcccg tctattgggt 11520 caccggatac cctgtcagct ccctaaccca cttttccctg gtggagcggc cgcaatcatg 11580 aaggccctta ttgacttgac atatgcaaac ctcaccatgg agcttggaca ccaaattaat 11640 gttagggagg aaaatggtac ttatgctcaa gctgctgcgc tcctcttcgc atcgattgca 11700 tccatgccac acttcacatt gggatctcac cccgtcaaga gggtgtcggt gctgtatcat 11760 cataacaaga ctgaccattg cttcggcgtg cgcttacaca tcgccacgca tttttgcaac 11820 cagacgaagc ttgaggtgaa ctgcatcaac gattacttac acacttgtca aattccacta 11880 tgtgcacacg gtaatctgtt atgtgttccc acccatgtgc ggtgcaatcc ctggtttgcc 11940 cgaaccagct tctttgatat gtacttgcgc agcttagcac tgtcagataa gcagaggtat 12000 cacaaatact tagactatca cgcacactta tcttttgcag ccccaataac atgtctgatt 12060 cttacaacat atgtcatatt tacgctaatg gcacgagtgc ggatttctgg ttaggatacg 12120 ccttcgatac cattatcgtg gcccaaccca tgttgttagt tcttgcagga ctaatcactt 12180 ggaagatgtt tagacttatt gttactcctg tgctaacatt actaacattg tacttgctgg 12240 gctttgaagt atacatcaca ataaaatcag gcttgcagag aagccaaggc gttattgcgt 12300 tgtgtcttgc aattttcaca cttaccggcg tgctcctcct gtacgtacgc aatttttgtc 12360 tcacattccg gcacgtagga ctccgtgcag cgtgtacagg gatcacatac ctcctgcata 12420 aagatggcag cacgtcgaag gtcgcgtcag aatggccgat cctcgtcgag acccatggca 12480 cgcaacgcac cgccaacggg acgcactggc cgccaacgtc gaaactatat cacgccggaa 12540 cagagatccg cggtgacact ggccaggcaa tacggatcag caagctccgc tagtcccgtt 12600 gcaggaataa caggcctgct taaaccacat tattcacctg acgcaactct cgtcacaggt 12660 gacgctcgcg aaatcggccc ggcagcatgc cgattgatcg ctagagcagc attagctctc 12720 gcacagggtc atggtgaaat catcgccaat gacgaagctt ttgtttttgc actaacccta 12780 cctcgcaaag gccgtaatgc gtaggtagta gctgcctata gactgactgc atttagccaa 12840 agcctcacac tatgcacggc cagtcgtagt aatagcctta taaaatagca cgctgaggtt 12900 gaaaaaaaaa aaaaaaa 12917 //