ID   J02146; SV 1; linear; viral cRNA; STD; VRL; 1413 BP.
XX
AC   J02146;
XX
DT   13-JUN-1985 (Rel. 06, Created)
DT   16-JUL-2016 (Rel. 129, Last updated, Version 8)
XX
DE   Influenza A virus (A/Puerto Rico/8/1934(H1N1)) segment 6, complete
DE   sequence.
XX
KW   complete genome; glycoprotein; neuraminidase.
XX
OS   Influenza A virus (A/Puerto Rico/8/1934(H1N1))
OC   Viruses; Riboviria; Negarnaviricota; Polyploviricotina; Insthoviricetes;
OC   Articulavirales; Orthomyxoviridae; Alphainfluenzavirus.
XX
RN   [1]
RP   1-206
RX   DOI; 10.1016/0042-6822(80)90271-8.
RX   PUBMED; 7445434.
RA   Blok J., Air G.M.;
RT   "Comparative nucleotide sequences at the 3' end of the neuraminidase gene
RT   from eleven influenza type A viruses";
RL   Virology 107(1):50-60(1980).
XX
RN   [2]
RP   1-1413
RX   DOI; 10.1038/290213a0.
RX   PUBMED; 7010182.
RA   Fields S., Winter G., Brownlee G.G.;
RT   "Structure of the neuraminidase gene in human influenza virus A/PR/8/34";
RL   Nature 290(5803):213-217(1981).
XX
RN   [3]
RP   141-233
RX   DOI; 10.1016/0042-6822(82)90337-3.
RX   PUBMED; 7080440.
RA   Blok J., Air G.M.;
RT   "Block deletions in the neuraminidase genes from some influenza A viruses
RT   of the N1 subtype";
RL   Virology 118(1):229-234(1982).
XX
DR   MD5; 6386bb189cef312fb532ca69ce1da227.
DR   EuropePMC; PMC114725; 11689620.
DR   EuropePMC; PMC18739; 10823895.
XX
CC   [2],[1] sequence determined either by analysis of cloned cdna
CC   fragments [2] or by analysis of cdna synthesized with either
CC   poly-adenylated vrna template or vrna template and dodecamer primer
CC   [1]. assignment of coding region by consideration of open reading
CC   frames. [3] compares this na sequence with 11 other influenza
CC   strains and finds that the strains collected from 1933-1935 have
CC   deletions of 33 to 48bp in their seg 6 vrna 3' ends. the sequence
CC   figure for [3] was unclear at the extreme 3' end (bases 228-233).
CC   Complete source information:
CC   influenza A/Puerto Rico/8/34 [2]: rna & cdna to rna from human;
CC   [1],[3]: cdna to rna grown in chicken embryos, originally from
CC   human. [3] specifies A/Puerto Rico/8/34(mt. sinai).
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1413
FT                   /organism="Influenza A virus (A/Puerto Rico/8/1934(H1N1))"
FT                   /segment="6"
FT                   /strain="A/Puerto Rico/8/1934(H1N1)"
FT                   /mol_type="viral cRNA"
FT                   /db_xref="taxon:211044"
FT   CDS             21..1385
FT                   /codon_start=1
FT                   /product="neuraminidase"
FT                   /db_xref="GOA:P03468"
FT                   /db_xref="InterPro:IPR001860"
FT                   /db_xref="InterPro:IPR033654"
FT                   /db_xref="InterPro:IPR036278"
FT                   /db_xref="UniProtKB/Swiss-Prot:P03468"
FT                   /protein_id="AAA43412.1"
FT                   /translation="MNPNQKIITIGSICLVVGLISLILQIGNIISIWISHSIQTGSQNH
FT                   TGICNQNIITYKNSTWVKDTTSVILTGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIRE
FT                   PFISCSHLECRTFFLTQGALLNDRHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVA
FT                   WSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECACVNGS
FT                   CFTIMTDGPSDGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNW
FT                   HGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGTGSCGPVYVDGANGVKGFSYRYGN
FT                   GVWIGRTKSHSSRHGFEMIWDPNGWTETDSKFSVRQDVVAMTDWSGYSGSFVQHPELTG
FT                   LDCIRPCFWVELIRGRPKEKTIWTSASSISFCGVNSDTVDWSWPDGAELPFTIDK"
XX
SQ   Sequence 1413 BP; 428 A; 253 C; 351 G; 381 T; 0 other;
     agcgaaagca ggggtttaaa atgaatccaa atcagaaaat aataaccatt ggatcaatct        60
     gtctggtagt cggactaatt agcctaatat tgcaaatagg gaatataatc tcaatatgga       120
     ttagccattc aattcaaact ggaagtcaaa accatactgg aatatgcaac caaaacatca       180
     ttacctataa aaatagcacc tgggtaaagg acacaacttc agtgatatta accggcaatt       240
     catctctttg tcccatccgt gggtgggcta tatacagcaa agacaatagc ataagaattg       300
     gttccaaagg agacgttttt gtcataagag agccctttat ttcatgttct cacttggaat       360
     gcaggacctt ttttctgacc caaggtgcct tactgaatga caggcattca aatgggactg       420
     ttaaggacag aagcccttat agggccttaa tgagctgccc tgtcggtgaa gctccgtccc       480
     cgtacaattc aagatttgaa tcggttgctt ggtcagcaag tgcatgtcat gatggcatgg       540
     gctggctaac aatcggaatt tcaggtccag ataatggagc agtggctgta ttaaaataca       600
     acggcataat aactgaaacc ataaaaagtt ggaggaagaa aatattgagg acacaagagt       660
     ctgaatgtgc ctgtgtaaat ggttcatgtt ttactataat gactgatggc ccgagtgatg       720
     ggctggcctc gtacaaaatt ttcaagatcg aaaaggggaa ggttactaaa tcaatagagt       780
     tgaatgcacc taattctcac tatgaggaat gttcctgtta ccctgatacc ggcaaagtga       840
     tgtgtgtgtg cagagacaat tggcatggtt cgaaccggcc atgggtgtct ttcgatcaaa       900
     acctggatta tcaaatagga tacatctgca gtggggtttt cggtgacaac ccgcgtccca       960
     aagatggaac aggcagctgt ggtccagtgt atgttgatgg agcaaacgga gtaaagggat      1020
     tttcatatag gtatggtaat ggtgtttgga taggaaggac caaaagtcac agttccagac      1080
     atgggtttga gatgatttgg gatcctaatg gatggacaga gactgatagt aagttctctg      1140
     tgaggcaaga tgttgtggca atgactgatt ggtcagggta tagcgggagt ttcgttcaac      1200
     atcctgagct aacagggcta gactgtataa ggccgtgctt ctgggttgaa ttaatcaggg      1260
     gacgacctaa agaaaaaaca atctggacta gtgcgagcag catttctttt tgtggcgtga      1320
     atagtgatac tgtagattgg tcttggccag acggtgctga gttgccattc accattgaca      1380
     agtagtctgt tcaaaaaact ccttgtttct act                                   1413
//