ID   HM745932; SV 1; linear; genomic RNA; STD; VRL; 1744 BP.
XX
AC   HM745932;
XX
DT   09-MAR-2011 (Rel. 108, Created)
DT   14-OCT-2011 (Rel. 110, Last updated, Version 3)
XX
DE   Phlebovirus HB29/China/2010 strain HB29 segment S, complete sequence.
XX
KW   .
XX
OS   SFTS virus HB29
OC   Viruses; Riboviria; Negarnaviricota; Polyploviricotina; Ellioviricetes;
OC   Bunyavirales; Phenuiviridae; Phlebovirus.
XX
RN   [1]
RP   1-1744
RX   DOI; 10.1056/NEJMoa1010095.
RX   PUBMED; 21410387.
RA   Yu X.J., Liang M.F., Zhang S.Y., Liu Y., Li J.D., Sun Y.L., Zhang L.,
RA   Zhang Q.F., Popov V.L., Li C., Qu J., Li Q., Zhang Y.P., Hai R., Wu W.,
RA   Wang Q., Zhan F.X., Wang X.J., Kan B., Wang S.W., Wan K.L., Jing H.Q.,
RA   Lu J.X., Yin W.W., Zhou H., Guan X.H., Liu J.F., Bi Z.Q., Liu G.H., Ren J.,
RA   Wang H., Zhao Z., Song J.D., He J.R., Wan T., Zhang J.S., Fu X.P.,
RA   Sun L.N., Dong X.P., Feng Z.J., Yang W.Z., Hong T., Zhang Y., Walker D.H.,
RA   Wang Y., Li D.X.;
RT   "Fever with thrombocytopenia associated with a novel bunyavirus in China";
RL   N. Engl. J. Med. 364(16):1523-1532(2011).
XX
RN   [2]
RP   1-1744
RA   Li J.D., Liang M.F., Sun Y.L., Zhang Q.F., Li C., Lu J., Qu J., Zhan F.X.,
RA   Guan X.H., Li D.X.;
RT   "A novel Phlebovirus related to severe fever with thrombocytopenia syndrome
RT   (SFTS) in humans";
RL   Unpublished.
XX
RN   [3]
RP   1-1744
RA   Li J.D., Liang M.F., Sun Y.L., Zhang Q.F., Li C., Lu J., Qu J., Zhan F.X.,
RA   Guan X.H., Li D.X.;
RT   ;
RL   Submitted (11-JUL-2010) to the INSDC.
RL   Department of Viral Hemorrhagic Fever, National Institute for Viral
RL   Diseases Control and Prevention, Changbai Road 155, Beijing 102206, China
XX
DR   MD5; 6fb35f68801c34b0bf6af590dbc7ba90.
DR   EuropePMC; PMC3165796; 21715500.
DR   EuropePMC; PMC4214719; 25356556.
DR   EuropePMC; PMC4337530; 25552716.
DR   EuropePMC; PMC5312432; 28202038.
XX
CC   GenBank Accession Numbers HM745930-HM745932 represent sequences
CC   from the 3 segments of Phlebovirus HB29/China/2010.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..1744
FT                   /organism="SFTS virus HB29"
FT                   /segment="S"
FT                   /host="Homo sapiens"
FT                   /strain="HB29"
FT                   /mol_type="genomic RNA"
FT                   /country="China"
FT                   /isolation_source="serum"
FT                   /collection_date="20-May-2010"
FT                   /db_xref="taxon:992212"
FT   CDS             43..780
FT                   /codon_start=1
FT                   /product="nucleocapsid protein"
FT                   /db_xref="GOA:F1BA48"
FT                   /db_xref="InterPro:IPR009522"
FT                   /db_xref="InterPro:IPR015971"
FT                   /db_xref="UniProtKB/TrEMBL:F1BA48"
FT                   /protein_id="ADZ04472.1"
FT                   /translation="MSEWSRIAVEFGEQQLNLTELEDFARELAYEGLDPALIIKKLKET
FT                   GGDDWVKDTKFIIVFALTRGNKIVKASGKMSNSGSKRLMALQEKYGLVERAETRLSITP
FT                   VRVAQSLPTWTCAAAAALKEYLPVGPAVMNLKVENYPPEMMCMAFGSLIPTAGVSEATT
FT                   KTLMEAYSLWQDAFTKTINVKMRGASKTEVYNSFRDPLHAAVNSVFFPNDVRVKWLKAK
FT                   GILGPDGVPSRAAEVAAAAYRNL"
FT   CDS             complement(835..1716)
FT                   /codon_start=1
FT                   /product="nonstructural protein"
FT                   /db_xref="GOA:F1BA49"
FT                   /db_xref="UniProtKB/TrEMBL:F1BA49"
FT                   /protein_id="ADZ04473.1"
FT                   /translation="MSLSKCSNVDLKSVAMNANTVRLEPSLGEYPTLRRDLVECSCSVL
FT                   TLSMVKRMGKMTNTVWLFGNPKNPLHQLEPGLEQLLDMYYKDMRCYSQRELSALRWPSG
FT                   KPSVWFLQAAHMFFSIKNSWAMETGRENWRGLFHRITKGQKYLFEGDMILDSLEAIEKR
FT                   RLRLGLPEILITGLSPILDVALLQIESLARLRGLSLNHHLFTSPSLRKPLLDCWDFFIP
FT                   VRKKKTDGSYSVLDEDDEPGVLHGYPHLMAHYLNRCPFHNLIRFDEELRTAALNTIWGR
FT                   DWPAIGDLPKEV"
XX
SQ   Sequence 1744 BP; 456 A; 413 C; 448 G; 427 T; 0 other;
     acacaaagac ccccaaaaaa ggaaagacgc aaaggagtga tcatgtcgga gtggtccagg        60
     attgcagtgg agtttggtga gcagcagctc aatttgactg agcttgagga cttcgcgaga       120
     gagctggcct atgaaggcct tgaccctgct ttgatcatca agaagctgaa ggagacaggt       180
     ggagatgatt gggtgaagga tacaaagttc atcattgtct ttgccctgac tcgaggcaat       240
     aagatcgtca aggcatcagg gaaaatgtca aactcagggt ccaagaggtt gatggcactc       300
     caagagaaat atggactggt tgagagggca gagaccaggc tctcaatcac tccagtgagg       360
     gttgcgcaga gccttcccac ttggacatgt gctgctgcag cagctctaaa ggagtatctc       420
     ccagtagggc cagccgtcat gaacctgaag gttgagaatt atccccctga gatgatgtgc       480
     atggcctttg gatccctgat tccaactgcg ggggtatctg aagccacaac caagaccctg       540
     atggaggcct actctctgtg gcaagatgcc ttcaccaaga ctatcaatgt aaagatgcgc       600
     ggagccagca agacagaagt ttacaactcc ttcagggacc ctcttcatgc tgctgtgaac       660
     tctgtcttct ttcccaatga tgttcgggta aagtggctga aggccaaggg gatccttggc       720
     ccagatgggg tccccagcag agctgctgag gttgctgctg ctgcttacag aaacctgtaa       780
     gcagcaattt gacatatcca attaggctaa aattcatgat ccaattcgac aaaattagac       840
     ctccttcggg aggtcaccaa tggctggcca atctcttccc cagatggtgt tcagggctgc       900
     agttctcagc tcttcatcaa acctgatgag gttgtggaaa gggcacctat ttaaatagtg       960
     tgccatcaga tgtgggtaac catgaaggac tccaggctca tcatcctcat ccaagacact      1020
     gtaagagcca tctgtcttct ttttgcggac aggaataaag aagtcccaac agtccaatag      1080
     aggcttacgc aatgagggag aagtgaataa gtggtggttc aagctcaggc ctcttagcct      1140
     tgcaagtgac tctatctgga ggagggccac atccagaatt ggggatagtc cagttattag      1200
     gatctcaggt aacccaagtc taagcctccg cttctcaatg gcttcaagag aatctaatat      1260
     catgtcccct tcaaaaaggt acttctggcc ttttgtaatc ctgtggaaga ggccccgcca      1320
     gttctctctt ccggtttcca ttgcccagct gttcttgatg gagaagaaca tgtgagctgc      1380
     ctgtaggaac catacagatg gttttccact aggccacctg agagcactca gctctctctg      1440
     ggagtagcac ctcatgtcct tgtagtacat gtccaacaac tgctcaagtc cgggctcaag      1500
     ctggtgaaga ggattttttg ggttgccaaa taaccaaaca gtgttggtca tcttacccat      1560
     cctcttgacc attgacagag tcaacacact acaagagcac tcaacgaggt ctctcctgag      1620
     agtggggtac tctcctagag atggctcaag cctgacagtg ttggcattca ttgctacaga      1680
     tttgaggtca acgttggagc atttgctcag cgacatggtt tccaaatgaa gggggtcttt      1740
     gtgt                                                                   1744
//