ID   D00355; SV 1; linear; genomic RNA; STD; VRL; 3050 BP.
XX
AC   D00355;
XX
DT   11-APR-1990 (Rel. 23, Created)
DT   07-JUL-2003 (Rel. 76, Last updated, Version 5)
XX
DE   Cucumber mosaic virus gene for large ORF, complete cds, RNA2.
XX
KW   RNA2.
XX
OS   Cucumber mosaic virus (cucumber mosaic cucumovirus)
OC   Viruses; Riboviria; Bromoviridae; Cucumovirus.
XX
RN   [1]
RP   1-3050
RX   PUBMED; 3404113.
RA   Rizzo T.M., Palukaitis P.;
RT   "Nucleotide sequence and evolutionary relationships of cucumber mosaic
RT   virus (CMV) strains: CMV RNA2";
RL   J. Gen. Virol. 69:1777-1787(1988).
XX
DR   MD5; c0e89ca5dc44e48951971912458b27d5.
DR   EuropePMC; PMC110906; 11044076.
DR   EuropePMC; PMC136033; 11884564.
DR   EuropePMC; PMC1781478; 17257060.
DR   EuropePMC; PMC416521; 15163757.
DR   GOA; P0C783.
DR   InterPro; IPR004946; Cucumo_2B.
DR   RFAM; RF01084; TLS-PK3.
DR   UniProtKB/Swiss-Prot; P0C783; 2B_CMVFN.
XX
CC   Submitted in computer readable form by Thomas,R. on 30/JAN/1989.
CC   The nucleotide sequence of RNA 2 of the Fny strain (Subgroup I) of
CC   cucumber mosaic virus (CMV) was determind and compared at both the
CC   nucleic acid and protein level with the previously determined
CC   corresponding sequence of RNA 2 of the Q strain (Subgroup 2) of
CC   CMV.  Fny-CMVRNAII2 consisted of 3050 nucleotides and contained a
CC   single open reading frame (ORF) of 2571 nucleoties, whereas
CC   Q-CMVRNA 2 consists of 3035 nucleotides and contains a single ORF
CC   of 2517 nucleotides. At the nucleotide level, there was 71%
CC   sequence homology between the two RNAs, while at the protein level
CC   sequence homology was 73%.  Protein homology was greater (89%) in
CC   the central third than in either the N-terminal (64%) or the
CC   C-terminal (56%) thirds. The secondary structures of the 3' end of
CC   the RNAs were very similar, even though the nucleotide sequence
CC   homology between the 3'-terminal 180 nucleotides was only 62%. By
CC   contrast, there was 80% sequence homology between the 5'-terminal
CC   86 residue, non-translated regions of the two RNAs.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..3050
FT                   /organism="Cucumber mosaic virus"
FT                   /segment="2"
FT                   /strain="Fny"
FT                   /mol_type="genomic RNA"
FT                   /note="5' end of RNA 2"
FT                   /db_xref="taxon:12305"
FT   CDS             87..2660
FT                   /codon_start=1
FT                   /product="large ORF"
FT                   /db_xref="GOA:P16490"
FT                   /db_xref="InterPro:IPR001788"
FT                   /db_xref="InterPro:IPR007094"
FT                   /db_xref="UniProtKB/Swiss-Prot:P16490"
FT                   /protein_id="BAA00263.1"
FT                   /translation="MAFPAPAFSLANLLNGSYGVDTPEDVERLRSEQREEAAAACRNYR
FT                   PLPAVDVSESVTEDAHSLRTPDGAPAEAVSDEFVTYGAEDYLEKSDDELLVAFETMVKP
FT                   MRIGQLWCPAFNKCSFISSIAMARALLLAPRTSHRTMKCFEDLVAAIYTKSDFYYSEEC
FT                   EADDAQIDISSRDVPGYSFEPWSRTSGFEPPPICEACDMIMYQCPCFDFNALKKSCAER
FT                   TFADDYVIEGLDGVVDNATLLSNLGPFLVPVKCQYEKCPTPTIAIPPDLNRATDRVDIN
FT                   LVQSICDSTLPTHSNYDDSFHQVFVESADYSIDLDHVRLRQSDLIAKIPDSGHMIPVLN
FT                   TGSGHKRVGTTKEVLTAIKKRNADVPELGDSVNLSRLSKAVAERFFISYINGNSLASSN
FT                   FVNVVSNFHDYMEKWKSSGLSYDDLPDLHAENLQFYDHMIKSDVKPVVSDTLNIDRPVP
FT                   ATITYHKKSITSQFSPLFTALFERFQRCLRERIILPVGKISSLEMAGFDVKNKHCLEID
FT                   LSKFDKSQGEFHLLIQEHILNGLGCPAPITKWWCDFHRFSYIRDRRAGVGMPISFQRRT
FT                   GDALTYFGNTIVTMAEFAWCYDTDQFEKLLFSGDDSLGFSLLPPVGDPSKFTTLFNMEA
FT                   KVMEPAVPYICSKFLLSDEFGNTFSVPDPLREVQRLGTKKIPYSDNDEFLFAHFMSFVD
FT                   RLKFLDRMSQSCIDQLSIFFELKYKKSGEEAALMLGAFKKYTANFQSYKELYYSDRRQC
FT                   ELINSFCSTEFRVERVNSNKQRKNYGIERRCNDKRRTPTGSYGGGEEAETKVSQTESTG
FT                   TRSQKSQRESAFKSQTIPLPTVLSSGWFGTDRVMPPCERGGVTRV"
XX
SQ   Sequence 3050 BP; 770 A; 686 C; 706 G; 888 T; 0 other;
     gtttatttac aagagcgtac ggttcaaccc ctgcctcccc tgtaaaactc cctagactta        60
     aatcttttct ttctagtatc ttttctatgg ctttccctgc ccccgcattc tcactagcca       120
     atcttttgaa cggcagttac ggtgtcgaca ctcccgagga tgtggaacgt ttgcgatctg       180
     agcaacgcga agaggctgct gcggcctgtc gtaattacag gcccctaccc gctgtggatg       240
     tcagcgagag tgtcacagag gacgcgcatt ccctccgaac tcctgacgga gctcccgctg       300
     aagcggtgtc tgatgagttt gtaacttatg gtgctgaaga ttaccttgaa aaatctgatg       360
     atgagctcct tgtcgctttt gagacgatgg tcaaacccat gcgtatcgga caactatggt       420
     gccctgcgtt taataaatgt tcttttattt ccagcattgc tatggccaga gctttgttgt       480
     tggcacctag aacatcccac cgaaccatga agtgttttga agacctggtc gcggctattt       540
     acactaaatc tgatttctac tacagtgaag agtgtgaagc cgacgacgct cagatagata       600
     tctcgtctcg cgatgtaccc ggttattctt tcgaaccgtg gtcccgaacg tctggatttg       660
     aaccgccgcc catttgtgaa gcgtgcgaca tgatcatgta ccagtgcccg tgttttgatt       720
     ttaatgcttt aaagaaatcg tgcgctgaga ggaccttcgc tgatgattat gttattgaag       780
     gtttagatgg tgttgttgat aatgcgactc tgttgtcgaa tttgggtcca tttttggtac       840
     ccgtgaagtg tcaatatgaa aaatgtccaa cgccaaccat cgcgattcct ccggatttaa       900
     accgtgctac tgatcgtgtt gatatcaatt tagttcaatc catttgtgac tcgactctgc       960
     ccactcatag taattacgac gactcttttc atcaagtgtt cgtcgaaagt gcagactatt      1020
     ctatagatct ggatcatgtt agacttcgac agtctgatct tattgcaaaa attccagatt      1080
     cagggcatat gataccggtt ctgaacaccg ggagcggtca caagagagta ggtacaacga      1140
     aggaggtcct tacagcaatt aagaaacgta atgctgacgt tccagagcta ggtgattccg      1200
     ttaatttgtc tagattgagt aaagctgtgg ctgagagatt cttcatttca tacatcaatg      1260
     gtaactctct agcatccagt aactttgtca atgtcgttag taacttccac gattacatgg      1320
     aaaaatggaa gtcctcaggt ctttcttatg atgatcttcc ggatcttcat gctgagaatt      1380
     tgcagtttta tgaccacatg ataaaatccg atgtgaaacc tgtggtgagc gacacactca      1440
     atatcgacag accggttcca gctactataa cgtatcataa gaagagtata acctcccagt      1500
     tctcaccgtt attcacagcg ctattcgagc gcttccagag atgccttcga gaacgtatta      1560
     ttcttcctgt tggtaagatt tcatcccttg agatggcagg atttgatgtc aagaacaagc      1620
     actgcctcga gattgacctg tctaagtttg ataagtctca aggtgaattt cacttgctaa      1680
     tccaggaaca cattttgaat ggtctaggat gtccagctcc gataactaag tggtggtgtg      1740
     atttccatcg attctcttac attagagacc gtagagctgg tgttggtatg cctattagtt      1800
     tccagagacg aactggcgat gcactcactt attttggcaa taccatcgtc accatggctg      1860
     agtttgcctg gtgttatgac accgaccaat tcgaaaagct tttattctca ggcgatgatt      1920
     ctctaggatt ttcactgctt ccccctgttg gtgacccgag taaattcaca actcttttca      1980
     acatggaagc taaggtgatg gaacctgccg taccatatat ttgttcgaag ttcttactct      2040
     ctgacgagtt cggtaacaca ttttccgttc cagatccatt gcgcgaggtt cagcggttag      2100
     gaacaaagaa aattccctat tctgacaatg atgaattctt gtttgctcac ttcatgagct      2160
     ttgttgatcg attgaagttt ttggaccgaa tgtctcagtc gtgtatcgat caactttcga      2220
     ttttcttcga attgaaatac aagaagtctg gggaagaggc tgctttaatg ttaggcgcct      2280
     ttaagaagta taccgctaat ttccagtcct acaaagaact ctattattca gatcgtcgtc      2340
     agtgcgaatt gatcaattcg ttttgtagta cagagttcag ggttgagcgt gtaaattcca      2400
     acaaacagcg aaagaattat ggaattgaac gtaggtgcaa tgacaaacgt cgaactccaa      2460
     ctggctcgta tggtggaggc gaagaagcag agacgaaggt ctcacaaaca gaatcgacgg      2520
     gaacgaggtc acaaaagtcc cagcgagaga gcgcgttcaa atctcagact attccgcttc      2580
     ctaccgttct atcaagtgga tggttcggaa ctgacagggt catgccgcca tgtgaacgtg      2640
     gcggagttac ccgagtctga ggcctctcgt ttagagttat cggcggaaga ccatgatttt      2700
     gacgatacag attggttcgc cggtaacgaa tgggcggaag gtgctttctg aaacctcccc      2760
     ttccgcatct ccctccggtt ttctgtggcg ggagctgagt tggcagtatt gctataaact      2820
     gtctgaagtc actaaacaca ttgtggtgaa cgggttgtcc atccagctta cggctaaaat      2880
     ggtcagtcgt agaggaatct acgccagcag acttacaagt ctctgaggca cctttgaaac      2940
     catctcctag gtttcttcgg aaggacttcg gtccgtgtac ttctagcaca acgtgctagt      3000
     ttcagggtac gggtgccccc cacttttgtg gggcctccaa aaggagacca                 3050
//