Dbfetch
ID D00239; SV 1; linear; genomic RNA; STD; VRL; 7133 BP. XX AC D00239; XX DT 11-APR-1990 (Rel. 23, Created) DT 09-OCT-2020 (Rel. 144, Last updated, Version 6) XX DE Human rhinovirus A1B , complete genome. XX KW HRV-1B. XX OS human rhinovirus A1B OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; OC Picornavirales; Picornaviridae; Enterovirus; Rhinovirus A. XX RN [1] RX PUBMED; 2826669. RA Hughes P.J., North C., Jellis C.H., Minor P.D., Stanway G.; RT "The nucleotide sequence of human rhinovirus 1B: molecular relationships RT within the rhinovirus genus"; RL J. Gen. Virol. 69:49-58(1988). XX DR MD5; e520fd9b2db1a052740f214e6b3f01b6. DR EuropePMC; PMC1081250; 15750090. DR EuropePMC; PMC112895; 10482628. DR EuropePMC; PMC114071; 11160660. DR EuropePMC; PMC1933019; 17460053. DR EuropePMC; PMC1949831; 17623054. DR EuropePMC; PMC2238069; 18057136. DR EuropePMC; PMC2630738; 18976575. DR EuropePMC; PMC3519643; 22828244. DR EuropePMC; PMC3737412; 23950960. DR EuropePMC; PMC3838063; 24048533. DR EuropePMC; PMC4851184; 27199901. DR EuropePMC; PMC5056400; 27721388. DR EuropePMC; PMC5059946; 27383422. DR EuropePMC; PMC5355621; 28100614. DR RFAM; RF00229; IRES_Picorna. DR RFAM; RF00386; Entero_5_CRE. XX CC The complete nucleotide sequence of human rhinovirus 1B was CC determined. Extensive homology was found with serotype 2 and 89 but CC the similarity to serotype 14 was considerably less. XX FH Key Location/Qualifiers FH FT source 1..7133 FT /organism="human rhinovirus A1B" FT /mol_type="genomic RNA" FT /clone="pUB512 and others" FT /db_xref="taxon:2777147" FT CDS 623..7096 FT /codon_start=1 FT /product="polyprotein precursor" FT /db_xref="GOA:P12916" FT /db_xref="InterPro:IPR000081" FT /db_xref="InterPro:IPR000199" FT /db_xref="InterPro:IPR000605" FT /db_xref="InterPro:IPR001205" FT /db_xref="InterPro:IPR001676" FT /db_xref="InterPro:IPR002527" FT /db_xref="InterPro:IPR003138" FT /db_xref="InterPro:IPR003593" FT /db_xref="InterPro:IPR007094" FT /db_xref="InterPro:IPR009003" FT /db_xref="InterPro:IPR014759" FT /db_xref="InterPro:IPR014838" FT /db_xref="InterPro:IPR027417" FT /db_xref="InterPro:IPR029053" FT /db_xref="InterPro:IPR033703" FT /db_xref="InterPro:IPR036203" FT /db_xref="InterPro:IPR036988" FT /db_xref="PDB:1XR6" FT /db_xref="UniProtKB/Swiss-Prot:P12916" FT /func_characterised="identical sequence" FT /protein_id="BAA00168.1" FT /translation="MGAQVSRQNVGTHSTQNSVSNGSSLNYFNINYFKDAASSGASRLD FT FSQDPSKFTDPVKDVLEKGIPTLQSPSVEACGYSDRIIQITRGDSTITSQDVANAVVGY FT GVWPHYLTPQDATAIDKPTQPDTSSNRFYTLESKHWNGDSKGWWWKLPDALKEMGIFGE FT NMYYHFLGRSGYTVHVQCNASKFHQGTLLVAMIPEHQLASAKNGSVTAGYNLTHPGEAG FT RVVGQQRDANLRQPSDDSWLNFDGTLLGNLLIFPHQFINLRSNNSATLIVPYVNAVPMD FT SMLRHNNWSLVIIPISPLRSETTSSNIRPITVSISPMCAEFSGARAKNVRQGLPVYITP FT GSGQFMTTDDMQSPCALPWYHPTKEISIPGEVKNLIEMCQVDTLIPVNNVGTNVGNISM FT YTVQLGNQMDMAQEVFAIKVDITSQPLATTLIGEIASYYTHWTGSLRFSFMFCGTANTT FT LKLLLAYTPPGIDKPATRKDAMLGTHVVWDVGLQSTISLVVPWVSASHFRLTANDKYSM FT AGYITCWYQTNLVVPPNTPQTADMLCFVSACKDFCLRMARDTDLHIQSGPIEQNPVENY FT IDEVLNEVLVVPNIKESHHTTSNSAPLLDAAETGHTSNVQPEDAIETRYVMTSQTRDEM FT SIESFLGRSGCVHISRIKVDYNDYNGVNKNFTTWKITLQEMAQIRRKFELFTYVRFDSE FT VTLVPCIAGRGDDIGHVVMQYMYVPPGAPIPKTRNDFSWQSGTNMSIFWQHGQPFPRFS FT LPFLSIASAYYMFYDGYDGDNSSSKYGSIVTNDMGTICSRIVTEKQEHPVVITTHIYHK FT AKHTKAWCPRPPRAVPYTHSRVTNYVPKTGDVTTAIVPRASMKTVGPSDLYVHVGNLIY FT RNLHLFNSEMHDSILVSYSSDLIIYRTNTTGDDYIPSCNCTEATYYCKHKNRYYPIKVT FT PHDWYEIQESEYYPKHIQYNLLIGEGPCEPGDCGGKLLCRHGVIGIITAGGEGHVAFTD FT LRQFQCAEEQGITDYIHMLGEAFGNGFVDSVKEQINAINPINSISKKVIKWLLRIISAM FT VIIIRNSSDPQTIIATLTLIGCNGSPWRFLKEKFCKWTQLTYIHKESDSWLKKFTEMCN FT AARGLEWIGNKISKFIDWMKSMLPQAQLKVKYLNEIKKLSLLEKQIENLRAADNATQEK FT IKCEIDTLHDLSCKFLPLYAHEAKRIKVLYNKCSNIIKQRKRSEPVAVMIHGPPGTGKS FT ITTNFLARMITNESDVYSLPPDPKYFDGYDNQSVVIMDDIMQNPDGEDMTLFCQMVSSV FT TFIPPMADLPDKGKPFDSRFVLCSTNHSLLAPPTISSLPAMNRRFFFDLDIVVHDNYKD FT AQGKLNVSKAFQPCNVNTKIGNAKCCPFVCGKAVSFKDRSTCSTYTLAQVYNHILEEDK FT RRRQVVDVMSAIFQGPISLDAPPPPAIADLLQSVRTPEVIKYCQDNKWIVPAECQIERD FT LSIANSIITIIANIISIAGIIFVIYKLFCTLQGPYSGEPKPKTKMPERRVVAQGPEEEF FT GRSILKNNTCVITTDNGKFTGLGIYDRTLIIPTHADPGREVQVNGIHTKVLDSYDLYNR FT DGVKLEITVIQLDRNEKFRDIRKYIPETEDDYPECNLALSANQVEPTIIKVGDVVSYGN FT ILLSGNQTARMLKYNYPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTDTQ FT GQIKISKHANECGLPTIHTPSKTKLQPSVFYDVFPGSKEPAVSRDNDPRLKVNFKEALF FT SKYKGNTECSLNQHMEIAIAHYSAQLITLDIDSKPIALEDSVFGIEGLEALDLNTSAGF FT PYVTMGIKKRDLINNKTKDISRLKEALDKYGVDLPMITFLKDELRKKEKISAGKTRVIE FT ASSINDTILFRTTFGNLFSKFHLNPGVVTGSAVGCDPETFWSKIPVMLDGDCIMAFDYT FT NYDGSIHPVWFQALKKVLENLSFQSNLIDRLCYSKHLFKSTYYEVAGGVPSGCSGTSIF FT NTMINNIIIRTLVLDAYKNIDLDKLKIIAYGDDVIFSYKYTLDMEAIANEGKKYGLTIT FT PADKSTEFKKLDYNNVTFLKRGFKQDEKHTFLIHPTFPVEEIYESIRWTKKPSQMQEHV FT LSLCHLMWHNGRKVYEDFSSKIRSVSAGRALYIPPYDLLKHEWYEKF" FT mat_peptide 623..829 FT /product="VP4 protein" FT mat_peptide 830..1618 FT /product="VP2 protein" FT mat_peptide 1619..2332 FT /product="VP3 protein" FT mat_peptide 2333..3193 FT /product="VP1 protein" FT mat_peptide 3194..3619 FT /product="P2-A protein" FT mat_peptide 3620..3904 FT /product="P2-B protein" FT mat_peptide 3905..4870 FT /product="P2-C protein" FT mat_peptide 4871..5101 FT /product="P3-A protein" FT mat_peptide 5102..5164 FT /product="VPg protein" FT mat_peptide 5165..5713 FT /product="protease" FT mat_peptide 5714..7093 FT /product="polymerase" FT polyA_site 7133 XX SQ Sequence 7133 BP; 2380 A; 1288 C; 1387 G; 2078 T; 0 other; ttaaaactgg gtgtgggttg ttcccactca caccacccaa tgggtgttgt actctgttat 60 tccggtaact ttgtacgcca ttttccctcc ctccccatcc ttttacgtaa cttacaactt 120 ttaaacacaa gaccaatagt aggcaactct ccaggttgtc taaggtcaag cacttctgtt 180 tccccggttg acgttgatat gctctaacag ggcaaaaaca actgatatcg ttacccgcaa 240 agtgcctaca cagagcttag taggattctg aaagatcttt ggttggtcgc tcagctgcat 300 acccagcagt agaccttgca gatgaggctg gacattcccc actggtaaca gtggtccagc 360 ctgcgtggct gcctgcacac tcttatgagg tgtgaagcca aagattggac agggtgtgaa 420 gagccgcgtg tgctcacttt gagtcctccg gcccctgaat gcggctaacc ttaaacctgc 480 agccatggct cataaaccaa tgagcttatg gtcgtaatga gcaattgcgg gatgggaccg 540 actactttgg gtgtccgtgt ttcacttttt cctttatcaa ttgcttatgg tgacaatata 600 tacatagata tatattggca tcatgggtgc ccaggtatct aggcaaaatg ttggtacaca 660 ctcaactcaa aattcagtgt caaatggatc aagtttaaat tacttcaata taaattactt 720 taaggatgct gcttcgagtg gtgcatccag attagacttc tctcaagatc caagcaaatt 780 cactgatcca gttaaagatg tcttagaaaa aggaatccca acactacaat caccatctgt 840 tgaagcttgt ggctattcag ataggattat acaaataacc agaggagact caacaatcac 900 atcccaggac gtggcaaatg ctgtggttgg atatggggtt tggccacact acttaacccc 960 acaagatgca accgccatag acaaaccaac acaacccgat acatcatcaa ataggttcta 1020 tacactagaa agtaaacact ggaatggtga ttctaaagga tggtggtgga aattaccaga 1080 tgctcttaaa gaaatgggca tttttggaga gaatatgtat tatcacttct tgggtagaag 1140 tggatataca gttcacgtac agtgtaatgc tagcaaattc catcaaggta ccctcttagt 1200 tgcaatgata ccagaacatc aactagcaag tgcaaagaat ggaagtgtaa ctgctggtta 1260 taatctcaca cacccaggtg aggccggtag agttgtgggt caacagcgtg atgccaatct 1320 aaggcaacct agcgatgata gctggcttaa ttttgatggc actcttcttg gaaatctgtt 1380 aattttccca catcagttta taaatcttag aagtaataat tctgcaactt tgatagtacc 1440 atatgtgaat gctgtaccaa tggattcaat gcttcgacac aataattgga gtttagtcat 1500 tataccaatc agtccattac gtagtgaaac cacatcttct aacataagac caatcactgt 1560 atcaattagt cctatgtgtg ctgaattttc tggtgcaaga gcaaagaatg tcagacaagg 1620 tttacctgta tatataactc caggatctgg gcaatttatg acgactgatg acatgcagtc 1680 accttgtgca ctaccatggt accatcctac taaggaaata tctattccag gtgaagttaa 1740 aaacctcata gagatgtgtc aagtggatac cttaatccca gtcaataatg tgggtaccaa 1800 tgttggaaac attagtatgt acactgtgca attaggaaac caaatggata tggcacagga 1860 agtctttgca ataaaagtag atattacatc acaaccttta gctacaaccc taattggaga 1920 aattgcaagt tattataccc actggactgg aagtttacga tttagtttca tgttttgtgg 1980 gactgcaaac accacactta aattattact tgcatacaca ccacctggga ttgacaagcc 2040 agctaccaga aaagatgcaa tgctgggaac acatgttgtg tgggatgtcg gtttgcaatc 2100 taccatatct cttgttgtac catgggtaag tgccagtcat tttaggttaa ctgcaaatga 2160 caaatattcg atggctggtt atattacatg ttggtatcaa actaatctag tagtgccccc 2220 aaacacgcca caaactgctg acatgttgtg ttttgtttct gcatgtaagg acttttgtct 2280 acggatggct agggatacag atttacatat acaaagtggt ccaatagagc aaaatccagt 2340 ggaaaattac attgatgaag ttttaaatga agttctagta gtaccaaata taaaagaaag 2400 ccatcacact acatcaaatt ctgctccact cttggatgct gcagagacag gacacaccag 2460 taatgtacaa ccagaggatg ctatagaaac aagatatgtt atgacatcac aaacaagaga 2520 tgagatgagt atagaaagtt ttcttggtag atctggctgt gtgcatattt caagaataaa 2580 ggttgattac aatgactaca atggagtgaa caaaaacttt acaacatgga aaatcacact 2640 gcaggagatg gcacaaatta gaagaaaatt cgaactattt acttatgtta ggtttgattc 2700 agaagtaact ttagtaccct gtattgctgg tagaggagat gacattggtc atgttgtaat 2760 gcagtatatg tatgttcccc caggagctcc aattccaaaa acaagaaatg atttctcatg 2820 gcaatcaggc actaatatgt caatattctg gcaacatgga caaccgttcc ctagattctc 2880 tttaccattt cttagcattg cgtcagctta ttacatgttt tatgatggat atgatggaga 2940 taattcctct tccaaatatg gtagtatagt caccaatgat atgggaacca tatgttcaag 3000 aatagttaca gagaagcagg aacaccctgt cgttattaca acacacatat atcacaaagc 3060 taaacacaca aaagcttggt gccctagacc tcctagagct gttccttaca cacatagtcg 3120 tgtaactaat tatgtaccaa aaacaggtga tgtgacaaca gctatagttc ctagagctag 3180 catgaaaact gttggaccca gtgatttgta tgtacatgta ggtaacttaa tatataggaa 3240 tttacatttg tttaactctg aaatgcatga ttcaattctg gtttcatact cttctgattt 3300 aatcatatac cgcacaaaca ctacaggtga tgattatatt cctagttgta actgcacaga 3360 ggctacctat tattgtaaac acaaaaatag atattaccca ataaaggtta ctccacatga 3420 ttggtatgaa atccaagaaa gtgaatatta ccctaaacat atccaataca atttattaat 3480 tggtgaagga ccatgtgaac ctggtgattg tggtgggaaa cttctttgta gacatggtgt 3540 tattggcata attacagcag gtggtgaagg ccatgtagca tttacagatc ttagacagtt 3600 tcaatgtgct gaagaacagg gtataactga ttatatacac atgttaggag aggcctttgg 3660 taatggtttt gtagatagtg tcaaagaaca aattaatgca ataaatccaa tcaatagcat 3720 tagcaaaaaa gttatcaagt ggctacttag aataatttca gctatggtca ttataattag 3780 aaattcttct gaccctcaaa caatcatagc aactctaact ttaattggct gcaatggttc 3840 gccatggagg tttctcaagg aaaagttttg taaatggacc caattaactt acatccacaa 3900 agaatctgat tcatggctca agaaatttac tgaaatgtgt aatgccgcgc gtggtcttga 3960 gtggattggc aataaaattt caaagttcat agattggatg aaatcaatgc tacctcaggc 4020 tcagttgaaa gtcaaatatc tgaatgagat aaagaaactt agcttgcttg aaaaacaaat 4080 tgaaaatcta cgcgcagcag ataatgctac acaagaaaag atcaaatgtg aaattgacac 4140 cttgcatgac ttatcatgta aatttctccc tttatacgca catgaagcaa aaaggattaa 4200 agtgctctac aataaatgtt ccaatataat caaacaaaga aagagaagtg agccagtggc 4260 agtaatgata catggaccac ctggtactgg taagtctata acaaccaatt tcctagccag 4320 aatgataaca aatgaaagtg atgtgtattc attaccccca gatcctaaat attttgatgg 4380 atatgacaat cagagtgttg tgatcatgga tgatatcatg cagaaccctg atggagaaga 4440 catgacacta ttttgtcaaa tggtttcaag tgttacattc ataccaccta tggctgacct 4500 gcctgataag ggtaagccgt ttgactcaag atttgttttg tgtagtacta atcactctct 4560 cctagctcca cccaccatat cttcattacc tgcaatgaac agaaggtttt tctttgactt 4620 agatattgta gttcatgata attacaagga tgcacaaggg aaattaaatg tatctaaggc 4680 tttccaacct tgtaatgtca atactaaaat tggcaatgca aaatgttgtc catttgtgtg 4740 tggtaaggca gtgtcattta aggatcgtag cacttgttca acatatacct tggctcaagt 4800 ttacaatcac attttggaag aagataagag aaggagacag gtggtagatg taatgtctgc 4860 aattttccaa gggccaattt ctctagatgc tccgccgcca ccagccatag cagatctgtt 4920 acaatcagtt agaacacctg aagtaattaa atattgtcag gacaacaaat ggatagtccc 4980 agcagaatgc caaatagaga gagacttaag catagccaat agcataataa ctattatagc 5040 aaatataata agtatagctg gtattatatt tgtaatttac aaattgtttt gcacactaca 5100 aggaccatac tcaggtgagc ctaaacccaa aaccaagatg cctgaaagga gagtagttgc 5160 ccaaggtcca gaagaagaat ttggaagatc aatcttaaag aacaacactt gtgtgattac 5220 tacagacaat ggaaaattta caggtcttgg tatctatgac agaactttga tcattccaac 5280 acatgctgat ccaggtagag aggttcaagt caacggcatt cacactaagg tcttagattc 5340 atatgacctt tataataggg atggagttaa acttgaaata acagttatac agttagatag 5400 aaatgaaaaa tttagggata ttaggaagta catacctgaa acagaggatg attatccaga 5460 atgtaattta gcactttcag ctaatcaagt tgaaccaact ataattaaag taggggatgt 5520 agtgtcttat ggtaacattt tacttagtgg gaaccaaaca gctagaatgc taaaatataa 5580 ttaccctaca aaatcaggat attgtggagg tgtattatat aaaattggtc agattctagg 5640 tattcatgta ggtggaaatg gaagagatgg attttcagcc atgttactta ggtcatactt 5700 tacagacact cagggtcaga ttaaaatctc caaacatgct aatgaatgtg gtcttccaac 5760 catacatacc cctagtaaaa ctaaacttca acctagtgtg ttctacgatg tcttcccagg 5820 ttctaaggaa ccagctgtct cacgagataa tgaccctaga ctaaaagtta attttaaaga 5880 agctctattc tctaaatata aaggtaatac agaatgtagt ttaaatcaac atatggaaat 5940 tgccatcgct cactattcag cacaattaat aacattagat attgattcta aaccaatagc 6000 attagaggac agtgtgttcg ggatagaggg gctcgaagct ttagacttaa acactagtgc 6060 tggttttcct tatgttacaa tgggcatcaa aaagagagac ctaataaata ataaaacaaa 6120 agacatatct agacttaaag aggctttaga taaatatggt gttgacttgc ctatgattac 6180 tttcttaaag gatgaactta gaaagaagga gaaaatctca gcaggtaaaa ctagagttat 6240 agaagcaagt agcataaatg atacaatact atttagaact acttttggta acttattctc 6300 taagtttcac ttgaatccag gtgttgttac tggttctgca gtagggtgtg atcctgagac 6360 tttctggtcc aaaatccctg ttatgcttga tggagactgc ataatggcct ttgattatac 6420 aaactatgat ggtagcatac accctgtttg gtttcaagct ttaaagaaag ttcttgaaaa 6480 cttatccttt caatctaatt taattgatag gttgtgttac tctaagcatt tgtttaagtc 6540 aacatactat gaagtggcag gtggagttcc ttctggatgt tctgggacta gcatatttaa 6600 tactatgatt aataacatta taataagaac attagtttta gatgcatata agaatattga 6660 tttggacaag ttgaaaataa tcgcatatgg tgatgatgtg attttttctt acaagtatac 6720 tttagatatg gaagccattg ctaatgaagg aaagaaatat ggactcacaa taacaccagc 6780 agataaatct actgaattca agaaacttga ttacaacaat gtgacttttc ttaaacgtgg 6840 ttttaaacaa gatgagaaac acacatttct tattcacccc acatttccag tagaagaaat 6900 atatgaatca attagatgga ctaagaagcc ttcacaaatg caagaacatg tactatcatt 6960 atgccatttg atgtggcaca atggacgtaa ggtgtatgag gatttttcca gtaagatacg 7020 cagtgtcagc gctggtcgtg cactgtatat cccaccttat gatctattaa agcatgaatg 7080 gtatgaaaaa ttttagatat agaaataatg aatgaatgat tctttaattc tat 7133 //