Dbfetch
ID AF092942; SV 1; linear; genomic RNA; STD; VRL; 15140 BP. XX AC AF092942; XX DT 18-DEC-1998 (Rel. 58, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 3) XX DE Bovine respiratory syncytial virus strain ATue51908, complete genome. XX KW . XX OS Bovine orthopneumovirus OC Viruses; Riboviria; Negarnaviricota; Haploviricotina; Monjiviricetes; OC Mononegavirales; Pneumoviridae; Orthopneumovirus. XX RN [1] RP 1-15140 RX PUBMED; 9847328. RA Buchholz U.J., Finke S., Conzelmann K.K.; RT "Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV RT NS2 is not essential for virus replication in tissue culture, and the human RT RSV leader region acts as a functional BRSV genome promoter"; RL J. Virol. 73(1):251-259(1999). XX RN [2] RP 1-15140 RA Buchholz U.J., Finke S., Conzelmann K.-K.; RT ; RL Submitted (18-SEP-1998) to the INSDC. RL Department of Clinical Virology, Federal Research Center for Virus Diseases RL of Animals, Paul-Ehrlich-Str. 28, Tuebingen D-72076, Germany XX DR MD5; 644dab7d2b0da3ed10b57847832302d5. DR EuropePMC; PMC103829; 9847328. DR EuropePMC; PMC111453; 10627529. DR EuropePMC; PMC116331; 10954520. DR EuropePMC; PMC1182632; 16051861. DR EuropePMC; PMC136874; 12414977. DR EuropePMC; PMC155099; 11932394. DR EuropePMC; PMC165239; 12857912. DR EuropePMC; PMC167228; 12885884. DR EuropePMC; PMC4027036; 24700100. DR EuropePMC; PMC4063758; 24945377. DR EuropePMC; PMC5656777; 28714847. XX FH Key Location/Qualifiers FH FT source 1..15140 FT /organism="Bovine orthopneumovirus" FT /strain="ATue51908" FT /mol_type="genomic RNA" FT /db_xref="taxon:11246" FT misc_RNA 1..45 FT /note="leader region" FT mRNA 46..572 FT /gene="NS1" FT /product="nonstructural protein 1" FT CDS 99..509 FT /codon_start=1 FT /gene="NS1" FT /product="nonstructural protein 1" FT /db_xref="InterPro:IPR005099" FT /db_xref="UniProtKB/TrEMBL:Q77UT8" FT /protein_id="AAC96301.1" FT /translation="MGSETLSVIQVRLRNIYDNDKVALLKITCHTNRLILLTHTLAKSV FT IHTIKLSGIVFIHIITSSDYCPTSDIINSANFTSMPILQNGGYIWELMELTHCFQTNGL FT IDDNCEITFSKRLSDSELAKYSNQLSTLLGLN" FT mRNA 579..1072 FT /gene="NS2" FT /product="nonstructural protein 2" FT CDS 609..983 FT /codon_start=1 FT /gene="NS2" FT /product="nonstructural protein 2" FT /db_xref="InterPro:IPR004336" FT /db_xref="UniProtKB/TrEMBL:Q9YS29" FT /protein_id="AAC96302.1" FT /translation="MSTPNPETTAQRLIVNDMRPLSIETEIISLTKDIITHTFIYLINH FT ECIVRKLDERQATFTFLVNYEMKLLHKVGSTKYNKYTEYNRKYGTFPMPIFINHDGFLE FT CIGIKPTRNTPIIYKYDLNP" FT mRNA 1129..2330 FT /gene="N" FT /product="nucleoprotein" FT CDS 1144..2319 FT /codon_start=1 FT /gene="N" FT /product="nucleoprotein" FT /db_xref="GOA:Q77X51" FT /db_xref="InterPro:IPR004930" FT /db_xref="UniProtKB/TrEMBL:Q77X51" FT /protein_id="AAC96303.1" FT /translation="MALSKVKLNDTFNKDQLLSTSKYTIQRSTGDNIDIPNYDVQKHLN FT KLCGMLLITEDANHKFTGLIGMLYAMSRLGREDTLKILKDAGYQVRANGVDVITHRQDV FT NGKEMKFEVLTLVSLTSEVQGNIEIESRKSYKKMLKEMGEVAPEYRHDSPDCGMIVLCV FT AALVITKLAAGDRSGLTAVIRRANNVLRNEMKRYKGLIPKDIANSFYEVFEKYPHYIDV FT FVHFGIAQSSTRGGSRVEGIFAGLFMNAYGAGQVMLRWGVLAKSVKNIMLGHASVQAEM FT EQVVEVYEYAQKLGGEAGFYHILNNPKASLLSLTQFPNFSSVVLGNAAGLGIMGEYRGT FT PRNQDLYDAAKAYAEQLKENGVINYSVLDLTTEELEAIKNQLNPKDNDVEL" FT mRNA 2334..3202 FT /gene="P" FT /product="phosphoprotein" FT CDS 2351..3076 FT /codon_start=1 FT /gene="P" FT /product="phosphoprotein" FT /db_xref="GOA:Q9YS28" FT /db_xref="InterPro:IPR003487" FT /db_xref="UniProtKB/TrEMBL:Q9YS28" FT /protein_id="AAC96304.1" FT /translation="MEKFAPEFHGEDANTKATKFLESLKGKFTSSKDSRKKDSIISVNS FT VDIELPKESPITSTNQNINQPSEINDTIATNQVHIRKPLVSFKEELPSSENPFTRLYKE FT TIETFDNNEEESSYSYDEINDQTNDNITARLDRIDEKLSEIIGMLHTLVVASAGPTAAR FT DGIRDAMVGLREEMIEKIRSEALMTNDRLEAMARLRDEESEKMTKDTSDEVKLTPTSEK FT LNMVLEDESSDNDLSLEDF" FT mRNA 3211..4160 FT /gene="M" FT /product="matrix protein" FT CDS 3220..3990 FT /codon_start=1 FT /gene="M" FT /product="matrix protein" FT /db_xref="GOA:Q9YS27" FT /db_xref="InterPro:IPR005056" FT /db_xref="UniProtKB/TrEMBL:Q9YS27" FT /protein_id="AAC96305.1" FT /translation="METYVNKLHEGSTYTAAVQYNVIEKDDDPASLTIWVPMFQSSISA FT DLLIKELINVNILVRQISTLKGPSLKIMINSRSAVLAQMPSKFTISANVSLDERSKLAY FT DITTPCEIKACSLTCLKVKNMLTTVKDLTMKTFNPTHEIIALCEFENIMTSKRVVIPTF FT LRSINVKAKDLDSLENIATTEFKNAITNAKIIPYAGLVLVITVTDNKGAFKYIKPQSQF FT IVDLGAYLEKESIYYVTTNWKHTATKFSIKPIED" FT mRNA 4186..4651 FT /gene="SH" FT /product="small hydrophobic protein" FT CDS 4268..4513 FT /codon_start=1 FT /gene="SH" FT /product="small hydrophobic protein" FT /db_xref="GOA:Q9YS26" FT /db_xref="InterPro:IPR005327" FT /db_xref="UniProtKB/TrEMBL:Q9YS26" FT /protein_id="AAC96306.1" FT /translation="MNNTSTIIEFTGEFWTYFTLAFMMLTIGFFFIVTSLVAAILNKLC FT DFNDHHTNSLDIRTRLRNDTQLITRAHEGSINQSSN" FT mRNA 4690..5529 FT /gene="G" FT /product="attachment glycoprotein" FT CDS 4705..5478 FT /codon_start=1 FT /gene="G" FT /product="attachment glycoprotein" FT /db_xref="GOA:Q9YS25" FT /db_xref="InterPro:IPR000925" FT /db_xref="UniProtKB/TrEMBL:Q9YS25" FT /protein_id="AAC96307.1" FT /translation="MSNHTHHLKFKTLKRAWKASKYFIVGLSCLYKFNLKSLVQTALTT FT LAMITLTSLVITAIIYISVGNAKAKPTSKPTIQQTQQPQNHTSPFFTEHNYKSTHTSIQ FT STTLSQLPNTDTTRETTYSHSINETQNRKIKSQSTLPATRKPPINPSGSNPPENHQDHN FT NSQTLPYVPCSTCEGNLACLSLCQIGPERAPSRAPTITLKKTPKPKTTKKPTKTTIHHR FT TSPEAKLQPKNNTAAPQQGILSSPEHHTNQSTTQI" FT mRNA 5557..7458 FT /gene="F" FT /product="fusion glycoprotein precursor" FT CDS 5570..7294 FT /codon_start=1 FT /gene="F" FT /product="fusion glycoprotein precursor" FT /note="F0" FT /db_xref="GOA:Q9YS24" FT /db_xref="InterPro:IPR000776" FT /db_xref="PDB:5TDG" FT /db_xref="UniProtKB/TrEMBL:Q9YS24" FT /protein_id="AAC96308.1" FT /translation="MATTAMRMIISIIFISTYVTHITLCQNITEEFYQSTCSAVSRGYL FT SALRTGWYTSVVTIELSKIQKNVCKSTDSKVKLIKQELERYNNAVVELQSLMQNEPASF FT SRAKRGIPELIHYTRNSTKKFYGLMGKKRKRRFLGFLLGIGSAVASGVAVSKVLHLEGE FT VNKIKNALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKELLPQVNNHDCRISNIETVIE FT FQQKNNRLLEIAREFSVNAGITTPLSTYMLTNSELLSLINDMPITNDQKKLMSSNVQIV FT RQQSYSIMSVVKEEVIAYVVQLPIYGVIDTPCWKLHTSPLCTTDNKEGSNICLTRTDRG FT WYCDNAGSVSFFPQTETCKVQSNRVFCDTMNSLTLPTDVNLCNTDIFNTKYDCKIMTSK FT TDISSSVITSIGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYY FT VNKLEGKALYIKGEPIINYYDPLVFPSDEFDASIAQVNAKINQSLAFIRRSDELLHSVD FT VGKSTTNVVITTIIIVIVVVILMLIAVGLLFYCKTKSTPIMLGKDQLSGINNLSFSK" FT mRNA 7514..8473 FT /gene="M2" FT /product="matrix protein 2" FT CDS 7523..8083 FT /codon_start=1 FT /gene="M2" FT /product="matrix protein 2" FT /note="orf 1 of M2 gene" FT /db_xref="GOA:Q9YS23" FT /db_xref="InterPro:IPR000571" FT /db_xref="InterPro:IPR009452" FT /db_xref="InterPro:IPR036855" FT /db_xref="UniProtKB/TrEMBL:Q9YS23" FT /protein_id="AAC96309.1" FT /translation="MSRRNPCKYEIRGHCLNGKKCHFSHNYFEWPPHALLVRQNFMLNK FT ILKSMDRNNDTLSEISGAAELDRTEEYALGVIGVLESYLGSINNITKQSACVAMSKLLA FT EINNDDIKRLRNKEVPTSPKIRIYNTVISYIDSNKRNTKQTIHLLKRLPADVLKKTIKN FT TIDIHNEINGNNQGDIIVNEQNE" FT CDS 8076..8348 FT /codon_start=1 FT /gene="M2" FT /product="unknown" FT /note="orf 2 of M2 gene; putative alternate translation" FT /db_xref="InterPro:IPR009969" FT /db_xref="UniProtKB/TrEMBL:Q9YS22" FT /protein_id="AAC96310.1" FT /translation="MNNSNIIIFPEKYPCSISSLLIKNENDVIVLSHQNVLDYLQFQYP FT CNMYSQNHMLDDIYWTSQELIEDVLKILHLSGISISKYVIYVLVL" FT mRNA 8407..14979 FT /gene="L" FT /product="RNA dependent RNA polymerase" FT CDS 8414..14902 FT /codon_start=1 FT /gene="L" FT /product="RNA dependent RNA polymerase" FT /db_xref="GOA:Q9WKU5" FT /db_xref="InterPro:IPR014023" FT /db_xref="InterPro:IPR016269" FT /db_xref="InterPro:IPR025786" FT /db_xref="InterPro:IPR026890" FT /db_xref="InterPro:IPR039736" FT /db_xref="UniProtKB/TrEMBL:Q9WKU5" FT /protein_id="AAC96311.1" FT /translation="MDTLIHENSTNVYLTDSYLKGVISFSECNALGSYLLDGPYLKNDY FT TNIISRQKPLIEHINLKKLSIIQSFVTKYNKGELGLEEPTYFQSLLMTYKSLSTSELIT FT TTTLFKKIIRRAIEISDVKVYAILNKLGLKEKGKVDRCDDTNTTLSNIVRDNILSVISD FT NTPSTKKPNNSSCKPDQPIKTTILCKLLSSMSHPPTWLIHWFNLYTKLNDILTQYRTNE FT ARNHGYILIDTRTLGEFQFILNQYGCIVYHKKLKKITITTYNQFLTWKDISLSRLNVCM FT ITWISNCLNTLNKSLGLRCEFNNVTLSQLFLHGDCILKLFHNEGYYIIKEVEGFIMSLI FT LNLTEEDQFRKRFFNSMLNNITDAAARAQQDLLSRARHTILDKTISDNILNGKWLILLG FT KFLKLIKLAGANNLNNLSELYFLFRIFGHPMVDERQAMDAVRLNCNETKFYLLSSLSML FT RGAFIYRIIKGFVNTYNRWPTLRNAIVLPLRWINYYKLNTYPSLLELTEADLIILSGLR FT FYREFHLPKKVDLEVIINDKAISPPKNLIWTSFPKNYMPSHIQIYIEHERLKFTESDRS FT RRVLEYYLRNNRFSESDLYNCIVNQEYLNNPNHVISLTGKERELSVGRMFAMQPGMFRQ FT VQIMAEKLIAENILQFFPESLTRYGDLELQKILELKAGISNKANRCNDNYNNYISKCSI FT ITDLSKFNQAFRYETSCICSDVLDELHGVQSLFSWLHLTIPFATVICTYRHAPPYIRNH FT ITDLNKVDEQSGLYRYHMGGIEGWCQKLWTIEAISLLDLISIKGKFSITALINGDNQSI FT DISKPIKLNEGQTHAQADYLLALKSLKLLYKEYASIGHKLKGTETYISRDMQFMSKTIQ FT HNGVYYPASIKKVLRVGPWINTILDDFKVSMESIGSLTQELEYRGESLLCSLIFRNVWL FT YNQIALQLKNHALCHNKLYLDILKVLAHLKMFFNLDNIDTALTLYMNLPMLFGGGDPNL FT LYRSFYRRTPDFLTEAIAHSVFVLSYYTGHDLQDKLQDLPDDKLNKFLTCIITFDKNPN FT AEFVTLMRDPQALGSERQAKVTSEINRLAVTEVLSNAPNKIFAKSAQHYTTTEVDLNDV FT MQKIEPTYPHGLRVVYESLPFYKAEKIVNLISGTKSITNILEKTSAIDYTDIERAIDMM FT RKNITLLIRILPLDYNKAKLGLLSLNNLSITDISKYVRERSWSLSNIVGITSPSILYTM FT DIKYTTSTITSGIIIEKYNSNFLTRGERGPTKPWVGSSTQEKKTMPVYNRQVLTKKQKD FT QIDLLAKLDWVYASIDNKDEFMEVLCLGTLGLSYEKAKKLFPQYLSVNYLHRLTVSSRP FT CEFPASIPAYRTTNYHFDTSPINRILTEKYGDEDIDIVFQNCISFGLSLMSVVEQFTNV FT CPNRIILIPKLNEIHLMKPPIFTGDVDICKLNQVIQKQHMFLPDKISLSQYVELFLSNK FT TLKNSPHISSNLVLVHKMSDYFLHKYVLSTNLAGHWIMIIQLMKDSKGIFEKDWGEGYI FT TDHMFLDLNVFFDAYKTYLLCFHKGYGKAKLECDMNTSDLFCTLELIDISYWKSMSKVF FT LEQKVVKHIINQDSSLHRVRGCHSFKLWFLKRLNTSKFIVCPWVVNIDYHPTHMKAILT FT YMELTTMGLVHVDKLYTDQKHKLNDGFYTSNLFYINYNFSDNTHLLTKQIRVANSELID FT NYNTLYHPSPESLESILKRSNQSNNVIELKDYPIDKFQSPKGRGVSDITCISSNQKIKQ FT GYNNQDLYNLFPAVIIDKIVDHSGNIANINQMYTITPNQLTLISNGTSLYCMLPWHHIN FT RFNFVFSSTGCKISTKLILKDLKIKDPHCIAFIGEGAGNLLLRTVVELHPDIKYIYRSL FT KDCNDHSLPIEFLRLYNGHISIDYGENLTIPATDATNAIHWSYLHIRYAEPINLFVCDA FT ELPDLTNWSRIVSEWYKHVRCCKYCSTIDRSKLIVKYHAQDITDFKLNNISIVKTYVCL FT GSKLKGSEVYLVLTVGPSNIFPSFNVVQNAKLILSRTQNFPMPKKIDKDSVDANIKSLI FT PFLCYPITKKGIKAALSKLKDVVDGNILSYSIAGRNEVYSNKLINYKLLNILKWLDHIL FT NFRSLEFSYNHLYMIESTYPFLSELLNSLTTNELKKLIKVTGSVLYSLQHEL" FT misc_RNA 14980..15140 FT /note="trailer region" XX SQ Sequence 15140 BP; 5684 A; 2546 C; 2538 G; 4372 T; 0 other; acgcgaaaaa atgcgtataa caaacctgta catccaaaaa agatcggggc aaataaaacc 60 ttgaaaggga gttttcccct ctcttctttc tacagaaaat gggcagtgaa acattgagtg 120 taattcaagt cagattaagg aatatatatg ataatgataa agtagcattg cttaaaataa 180 catgtcatac caatagatta atacttctaa ctcacacatt ggccaaatca gtcatacata 240 caattaaatt aagtggtata gtattcatac atattataac cagtagtgat tactgtccta 300 catctgatat tatcaatagt gccaatttca cttcaatgcc tatattacaa aatggaggat 360 atatatggga attgatggag ttaacacatt gtttccaaac aaacggttta atagatgata 420 attgtgaaat aacattttct aaaaggttaa gtgattcaga attagctaaa tattcaaatc 480 aattatctac tcttcttggt ctgaattaga gccctaaatc aatagccaac accagatgga 540 ctaagctaac taaatgtaat agtttataaa aattaattgg ggcaaataaa tcagttcccc 600 aaccagccat gagcacccca aatcccgaaa ccactgctca gagattgata gtaaatgata 660 tgaggccatt atcaatagaa acagaaataa tatctttgac caaagatatt attacacata 720 cattcatata tctaataaac catgagtgta tagtacgcaa actcgatgaa cgacaggcca 780 catttacatt ccttgtcaat tatgaaatga agctattgca taaagtgggt agcacaaaat 840 acaataaata cacagaatac aacagaaaat atggtacatt tccaatgcct atatttatca 900 accatgatgg ttttttagag tgtataggta tcaagcctac aagaaatact cctataatat 960 ataagtatga tttaaatcca taggcacttt tcaaaattta attcacacag tgttatcttt 1020 tggtaccaat gtcaaccaaa ttcccacata gtgcatagta gtaattaaaa aagaaccagg 1080 ttagaaacaa aaaaaggtag agaataacaa caaacaaaaa tgaaatgtgg ggcaaataca 1140 aaaatggctc ttagcaaggt caaactaaat gacactttca acaaggatca actgttgtca 1200 accagcaaat atactattca acgtagtaca ggtgacaaca ttgatatacc caattacgat 1260 gtgcaaaaac atctcaataa gttgtgtggt atgctattaa taacagaaga tgccaatcat 1320 aaatttacag gactgatagg tatgttatat gctatgtccc gattggggag agaagatacc 1380 cttaaaatac tcaaagatgc aggctaccaa gtgagggcca atggggttga tgtgataaca 1440 catcgacagg atgtgaatgg aaaagaaatg aaatttgaag tgctaacatt agtcagctta 1500 acatcagaag ttcaaggtaa tatagaaata gagtcaagga agtcttacaa aaagatgcta 1560 aaagagatgg gagaggtagc tccagaatac agacatgact ctcctgattg tggtatgata 1620 gtgctatgtg ttgctgcttt ggttataaca aaattagcag caggtgatag gtcaggcctc 1680 actgcagtca ttaggagagc caacaatgta ctaaggaatg aaatgaaacg atacaaagga 1740 ctcatcccga aagatatagc caacagcttc tatgaagtat ttgaaaagta ccctcattac 1800 atagatgtat tcgtacattt tggcattgct caatcctcaa ctagaggagg tagtagggta 1860 gaaggaatct ttgcagggtt attcatgaat gcatatggag caggtcaagt gatgttaaga 1920 tggggtgtac tagccaaatc agtcaagaat attatgcttg gtcatgccag cgtacaagca 1980 gaaatggaac aggttgtaga agtctatgaa tatgcacaaa agttaggtgg agaagctggt 2040 ttttatcaca tactgaacaa ccctaaagca tcattgttat ccttaacaca attccccaat 2100 ttctctagtg tagtcctagg caatgctgca ggactaggta taatgggtga gtatagaggt 2160 acaccaagaa accaagactt gtatgatgct gccaaagcat atgcagaaca actaaaagag 2220 aatggggtca tcaattacag tgtattggat ctgactacag aggaattaga ggcaatcaag 2280 aaccaattga atcccaaaga taatgatgtg gaattgtgag ttaataaaaa catggggcaa 2340 atacgtcagt atggaaaaat ttgcacctga gtttcatgga gaagatgcca atacaaaagc 2400 aaccaagttt cttgaatccc taaaagggaa atttacttct tctaaggatt ctaggaaaaa 2460 agatagtata atatcagtta attccgtaga catagaatta cctaaagaga gtcctataac 2520 atctaccaat caaaatatca accaaccaag tgagatcaat gacactattg ctacaaatca 2580 agttcatata agaaagcctt tggtaagctt caaagaagaa ctgccatcaa gtgaaaaccc 2640 ctttacaagg ctgtataagg aaactataga aacatttgac aataatgaag aagaatcaag 2700 ctactcatat gatgagataa atgatcaaac aaatgataat ataacagcaa gactagatag 2760 gatagatgaa aaattaagcg agataatagg aatgctccat acattagttg tggctagtgc 2820 aggaccaaca gctgctcgtg acggtataag agatgccatg gtagggctcc gagaagagat 2880 gattgagaaa ataagatcag aagctttaat gaccaacgat aggttagaag caatggccag 2940 gcttagggat gaagaaagtg aaaagatgac aaaagataca tcagatgaag taaaattaac 3000 ccctacctca gagaagctga acatggtatt agaagatgaa agtagtgaca atgatctatc 3060 acttgaagat ttctgaatag caaccagccc acccactaac agattagtca gatagatcaa 3120 ccatcaatga taaagccacc taatcaacca gccaaccagt cactcaacca gcctgtgatt 3180 ccacatagtt agtaaaaata aagtaaaatt ggggcaaata tggagacata cgtgaacaaa 3240 ctccatgaag gatcaactta cacagctgct gttcagtaca atgtcataga aaaagatgat 3300 gatcctgcat ctctcacaat atgggttcct atgttccaat catccatctc tgctgatttg 3360 cttataaaag aactaatcaa tgtgaacata ttagttcgac aaatttctac tctgaaaggt 3420 ccttcattga agattatgat aaactcaaga agtgctgtac tagcccaaat gcccagcaaa 3480 tttaccataa gtgcaaatgt atcattggat gaacgaagca aattagcata tgacataact 3540 actccttgtg aaattaaggc ttgtagttta acatgtttaa aggtgaaaaa tatgctcaca 3600 actgtgaaag atctcaccat gaaaacattc aatcctaccc atgagatcat tgcactgtgt 3660 gaatttgaaa atatcatgac atccaaaaga gttgttatac caactttctt aaggtcaatc 3720 aatgtaaaag caaaggattt ggactcacta gagaatatag ctaccacaga gttcaaaaat 3780 gccatcacta atgctaaaat tataccttat gctgggttgg tattagttat cactgtaact 3840 gacaataaag gggcattcaa gtacattaaa ccacaaagtc aatttatagt agatcttggt 3900 gcatatctag agaaagagag catatattat gtaactacaa attggaaaca cacggccact 3960 aaattctcca ttaagcctat agaggactga ttctcacaca acttatctta acacaacaga 4020 agactccctt aataacttac taatcatcat tgtaatcgaa tcttatttgc tgctctatca 4080 accataatca tcatattttc tcaacctgat taacccttca attcatcttg tagattatac 4140 ctcagttaga taaataaaaa ttatgaatgc caacaaagat tatgtggggc aaataaaatc 4200 tgcatccaat caagtacagc atacaccaga aactcctcga atccaccagc tggttgaact 4260 tattacaatg aacaatacat ctaccataat agagtttact ggtgaatttt ggacttactt 4320 tacattagcc tttatgatgt taaccatagg ttttttcttt attgtcacat cattagtggc 4380 agcaatactg aacaaattat gtgacttcaa cgatcatcat acaaatagtc tagacatcag 4440 aactaggctt agaaatgata cacaattgat aacaagagca catgaaggat ccatcaacca 4500 atcaagcaac taagaggaca acaaaacaaa agaaaatagc aacatgcatc aaagttaagc 4560 aaaggaaaac cacaaagaat cagacaatca tcactcatat ctttttagtc tacaaatgct 4620 gcattatgta ctgttaatta gttatttaaa attaaactta aaaatggttt atggttacat 4680 acagatgttg gggcaaatac aagtatgtcc aaccataccc accatcttaa attcaagaca 4740 ttaaagaggg cttggaaagc ctcaaaatac ttcatagtag gattatcatg tttatataag 4800 ttcaatttaa aatcccttgt ccaaacggct ttgaccacct tagcaatgat aaccttgaca 4860 tcactcgtca taacagccat tatttacatt agtgtgggaa atgctaaagc caagcccaca 4920 tccaaaccaa ccatccaaca aacacaacag ccccaaaacc atacctcacc atttttcaca 4980 gagcacaact acaaatcaac tcacacatca attcaaagca ccacactgtc ccaactacca 5040 aacacagaca ccactagaga aactacatac agtcactcaa tcaacgaaac ccaaaacaga 5100 aaaatcaaaa gccaatccac tctacccgcc accagaaaac caccaattaa cccatcggga 5160 agcaaccccc ctgaaaacca ccaagaccac aacaactccc aaacactccc ctatgtgcct 5220 tgcagtacat gtgaaggtaa tcttgcttgt ttatcactct gccaaatcgg gccggagaga 5280 gcaccaagca gagcccctac aatcaccctc aaaaagactc caaaacccaa aaccaccaaa 5340 aagccaacca agacaacaat ccaccacaga accagccctg aagccaaact gcaacccaaa 5400 aacaacacgg cagctccaca acaaggcatc ctctcttcac cagaacacca cacaaatcaa 5460 tcaactacac agatctaaca acacacctcc atataatatc aattatgttc atatatagtt 5520 atttaaaaag atatgtataa ttcactaatt aaaactgggg caaataagga tggcgacaac 5580 agccatgagg atgatcatca gcattatctt catctctacc tatgtgacac atatcacttt 5640 atgccaaaac ataacagaag aattttatca atcaacatgc agtgcagtta gtagaggtta 5700 ccttagtgca ttaagaactg gatggtatac aagtgtggta acaatagagt tgagcaaaat 5760 acaaaaaaat gtgtgtaaaa gtactgattc aaaagtgaaa ttaataaagc aagaactaga 5820 aagatacaac aatgcagtag tggaattgca gtcacttatg caaaatgaac cggcctcctt 5880 cagtagagca aaaagaggga taccagagtt gatacattat acaagaaact ctacaaaaaa 5940 gttttatggg ctaatgggca agaagagaaa aaggagattt ttaggattct tgctaggtat 6000 tggatctgct gttgcaagtg gtgtagcagt gtccaaagta ctacacctgg agggagaggt 6060 gaataaaatt aaaaatgcac tgctatccac aaataaagca gtagttagtc tatccaatgg 6120 agttagtgtc cttactagca aagtacttga tctaaagaac tatatagaca aagagcttct 6180 acctcaagtt aacaatcatg attgtaggat atccaacata gaaactgtga tagaattcca 6240 acaaaaaaac aatagattgt tagaaattgc tagggaattt agtgtaaatg ctggtattac 6300 cacacctctc agtacataca tgttgaccaa tagtgaatta ctatcactaa ttaatgatat 6360 gcctataacg aatgaccaaa aaaagctaat gtcaagtaat gttcaaatag tcaggcaaca 6420 gagttattcc attatgtcag tggtcaaaga agaagtcata gcttatgttg tacaattgcc 6480 tatttatgga gttatagaca ccccctgttg gaaactacac acctctccgt tatgcaccac 6540 tgataataaa gaagggtcaa acatctgctt aactaggaca gatcgtgggt ggtattgtga 6600 caatgcaggc tctgtgtctt ttttcccaca gacagagaca tgtaaggtac aatcaaatag 6660 agtgttctgt gacacaatga acagtttaac tctgcctact gacgttaact tatgcaacac 6720 tgacatattc aatacaaagt atgactgtaa aataatgaca tctaaaactg acataagtag 6780 ctctgtgata acttcaattg gagctattgt atcatgctat gggaagacaa aatgtacagc 6840 ttctaataaa aatcgtggaa tcataaagac tttttccaat gggtgtgatt atgtatcaaa 6900 caaaggagta gatactgtat ctgttggtaa cacactatat tatgtaaata agctagaggg 6960 gaaagcactc tatataaagg gtgaaccaat tattaattac tatgatccac tagtgtttcc 7020 ttctgatgag tttgatgcat caattgccca agtaaacgca aaaataaacc aaagcctggc 7080 cttcatacgt cgatctgatg agttacttca cagtgtagat gtaggaaaat ccaccacaaa 7140 tgtagtaatt actactatta tcatagtgat agttgtagtg atattaatgt taatagctgt 7200 aggattactg ttttactgta agaccaagag tactcctatc atgttaggga aggatcagct 7260 cagtggtatc aacaatcttt cctttagtaa atgaaatgca taatgtttac aatctaaacc 7320 tcagaatcat aaatgtgatg agctaaattt actaatacat tcaaaagttc tatccgccaa 7380 gacctgcatt tttatcaggt cttacataag ctaaccttac atgctacact caactccatg 7440 ttgatagtta tataaaaata ttatattagt ctcaaagaat aaaattattt aacaaccaat 7500 cattcaaaaa gatggggcaa atatgtcacg aagaaatccc tgcaaatatg agattagggg 7560 acattgctta aatggtaaaa aatgtcattt tagtcataat tactttgaat ggcctccaca 7620 tgctttatta gtgaggcaaa attttatgct aaataagata ttaaaatcta tggacaggaa 7680 caacgatacc ctgtcagaaa taagtggtgc agcagagttg gatagaacag aagaatatgc 7740 attgggtgta ataggagttt tggaaagtta cctaggctct atcaataata taacaaaaca 7800 atcagcctgt gttgctatga gtaaactatt agccgagatt aacaatgatg acataaagag 7860 attgaggaac aaggaagtgc caacatcacc taagataaga atatataaca cagttatatc 7920 atatattgat agcaacaaga gaaacacaaa acaaactata catttgctta agagattgcc 7980 tgcagacgta cttaaaaaga caatcaagaa cactatagat attcacaacg aaataaatgg 8040 taataaccaa ggtgacataa ttgttaatga acaaaatgaa taactccaac attattattt 8100 tcccagaaaa atacccttgt agcatatcct ctttgctaat taagaatgaa aatgatgtta 8160 ttgtactaag tcatcaaaat gttcttgact acttacagtt tcaatatcca tgtaatatgt 8220 attctcaaaa tcatatgctt gatgatatct attggacatc acaggagcta attgaggatg 8280 tacttaagat tcttcatctt tctggcatat ccataagtaa gtatgtgata tatgttttag 8340 tgctatagta tataagtcac tcaactatta atcaacagcc acttcttcat agctagcaat 8400 atataaggac aaaatggata cactcattca tgagaactca actaatgttt acttaacaga 8460 tagttattta aaaggtgtca tctctttttc tgagtgcaat gccctgggaa gctacttgtt 8520 ggatggacct tatctaaaaa atgattatac caacatcata agtagacaga aaccattgat 8580 agaacatata aacttaaaaa aattgtctat catacagtct tttgtaacta agtataacaa 8640 aggagagctg ggtttagaag aacccactta ctttcaatct ttacttatga cttacaaaag 8700 tctgtctaca tcagaattaa tcacaactac aactctgttt aaaaagataa ttcgtagagc 8760 tatagaaata agtgatgtca aagtatatgc tatattgaac aaattgggtt taaaagaaaa 8820 gggaaaagtt gatagatgtg atgacactaa cacaacgcta tctaacatag taagagataa 8880 tatactctca gtcataagtg acaatactcc cagtactaaa aaaccaaata attcatcgtg 8940 taaaccagat cagccaatta aaacaacaat tttatgcaag cttttaagtt cgatgagtca 9000 tccccctaca tggttaatac attggtttaa tttatacaca aaattaaatg acatcttgac 9060 ccaatacaga acaaatgaag caagaaatca tggttacata cttatagata ctagaacctt 9120 gggtgaattc caatttatat taaatcaata tggttgcatt gtatatcata agaaattaaa 9180 gaaaattaca atcaccacat ataatcaatt tctaacatgg aaagacatta gcctcagtag 9240 attaaatgtt tgtatgatca cctggataag caattgttta aataccttga ataaaagcct 9300 tggattgaga tgtgagttta acaatgtcac tctatctcaa ttattccttc atggggattg 9360 tatattgaaa ttatttcata atgaaggtta ctatattata aaagaagttg aaggttttat 9420 aatgtcatta attttgaacc taacggaaga agatcaattc agaaaaagat tcttcaacag 9480 tatgctaaat aatattacag atgctgcagc aagagctcaa caagatttat tatcaagagc 9540 ccgccatact atattagaca aaacaatatc agataacata ttaaatggta aatggttaat 9600 tttattaggt aagtttctta aattgattaa attagctggt gctaataatc ttaataacct 9660 aagtgaactc tactttctct ttagaatatt tggacatccc atggtagatg aacggcaagc 9720 aatggatgct gtgagattaa actgtaatga aactaaattt tacttattga gtagccttag 9780 catgttaaga ggtgcattca tttatagaat tataaaggga tttgtaaaca catataatag 9840 gtggcctacc ttaaggaatg ctatagtttt acccttaaga tggataaatt actacaaact 9900 caatacttac ccatcattat tagaattaac agaagctgat ttgattatat tgtctggact 9960 gagattttat agagaattcc atctaccgaa aaaagtagat ttagaagtca taataaatga 10020 taaagcaata tcacctccca aaaaccttat ctggaccagt tttcccaaaa actatatgcc 10080 atcacacata cagatttaca tagaacatga aagactaaag tttactgaga gtgatagatc 10140 tagaagggtt ctggaatatt atttaaggaa taatagattc agtgagagtg acctatataa 10200 ctgtatagta aaccaggaat atcttaataa tccaaaccat gtaatatcat taacaggaaa 10260 agaaagagaa cttagtgtag gtaggatgtt tgcaatgcag ccaggcatgt tcagacaggt 10320 tcaaatcatg gctgagaaat tgatagctga gaacatctta caatttttcc ctgagagttt 10380 aacacggtat ggagatcttg aattacagaa aatattagaa ttaaaagcag gcattagcaa 10440 caaagcaaat cgctgtaatg ataactataa caattatatc agtaaatgtt ctataatcac 10500 tgatcttagc aagttcaatc aggcattcag gtatgaaacg tcatgcattt gtagcgatgt 10560 tttagatgaa ttacatggtg tacaatctct cttttcttgg ttgcatttaa ctattccttt 10620 tgccactgtt atatgtactt atagacatgc tccaccttac ataagaaatc atataacaga 10680 tcttaataag gttgatgagc aaagtggact gtatagatat catatgggtg gtatagaagg 10740 ttggtgtcaa aaattgtgga ctattgaagc gatatcttta ttagatttaa tatctatcaa 10800 ggggaaattt tcaatcacag ctttaatcaa tggtgataat caatcaattg atataagtaa 10860 gcctatcaaa ttaaatgaag gacaaactca tgcacaggct gattatctat tagcacttaa 10920 aagccttaag ttgttgtata aagaatatgc tagtataggt cataaactta aaggtacgga 10980 gacatatata tcccgtgata tgcaatttat gagtaaaacc attcagcata atggtgtata 11040 ctatcctgca agcatcaaaa aagtgctacg agtaggtcca tggataaaca caatactgga 11100 tgattttaaa gtaagtatgg agtctatagg tagtttgact caagagttag aatatagagg 11160 agaaagttta ctatgcagtt tgatttttag gaatgtctgg ttgtataatc aaattgcttt 11220 gcaacttaag aatcatgcat tatgtcacaa caaactgtat ctagatatct tgaaagtgtt 11280 agcacactta aaaatgtttt ttaaccttga taatatagat actgccctaa cactatatat 11340 gaatttgcca atgttatttg gtggtggaga cccaaattta ttatatcgga gtttctatag 11400 aagaactccg gattttctta cagaagctat agcacattct gtctttgtgc ttagttatta 11460 tacaggacat gatcttcaag ataaattaca agatttacca gatgataaat taaataagtt 11520 tcttacatgt atcataactt ttgataagaa ccctaatgca gaatttgtaa cattgatgag 11580 agatccacaa gctttagggt ctgagagaca agctaaagtc actagtgaaa ttaatagatt 11640 agcagtgaca gaagtattaa gcaatgcacc aaataaaata tttgctaaaa gtgcacaaca 11700 ttacactact actgaagttg atttaaatga tgtaatgcaa aaaatagagc cgacttaccc 11760 gcatggatta agagtggtct atgaaagtct tcctttctac aaagcagaaa aaattgttaa 11820 tttaatatca ggcactaaat ctatcaccaa tatacttgaa aaaacatctg ctattgatta 11880 tacagacatt gagagagcta tagatatgat gagaaagaat ataactttgc taattagaat 11940 tcttccatta gattacaata aagccaagtt gggattgtta agtctcaaca atcttagtat 12000 cactgatata agtaaatatg taagagaaag atcttggtca ctgtctaaca ttgtaggtat 12060 tacatctcct agcatattat atacaatgga tattaaatac accactagca ctataactag 12120 tggtataata attgaaaaat acaattccaa ttttttgact cgtggtgaga ggggtcccac 12180 taaaccatgg gtaggatcat caacccaaga aaagaaaaca atgcctgtat acaataggca 12240 ggttttaact aagaaacaaa aggatcaaat tgatttgttg gcaaaactag attgggttta 12300 tgcctctata gataacaaag atgagtttat ggaagtatta tgtttgggaa cacttggact 12360 atcctatgaa aaagccaaga aattgttccc tcaatacctg agtgtaaact acctgcatcg 12420 tcttacagtt agtagtagac catgtgagtt tccagcctca ataccagctt acagaacaac 12480 taattaccac tttgacacaa gtccaattaa tcgaatacta actgaaaaat atggtgatga 12540 agacattgat atagtgtttc agaattgtat cagttttggt cttagcttaa tgtcagttgt 12600 agaacaattt acaaatgtat gcccaaatag aattattcta ataccaaaac ttaatgaaat 12660 tcatttgatg aagccaccca tatttacagg tgatgttgac atttgtaagc ttaatcaggt 12720 gatacagaaa cagcatatgt ttttacctga taaaatcagt ttgtctcaat atgttgaatt 12780 gttccttagc aataaaacac ttaagaatag tccacatata agctctaatt tagtgttagt 12840 gcacaaaatg tctgattact ttttgcataa gtatgtttta agcacaaact tagcaggaca 12900 ttggataatg atcatacagc ttatgaaaga ttctaaaggg atttttgaga aggattgggg 12960 tgaaggatat ataactgatc atatgttttt agatttaaat gtcttttttg atgcatataa 13020 aacatatttg ttatgttttc ataaaggtta tggaaaagct aaattagaat gtgatatgaa 13080 tacatcagat cttttttgta cattagagtt aatagatatc agctattgga aatccatgtc 13140 caaggtgttc ttagaacaaa aagtagtgaa gcacataatt aatcaagatt ctagtctaca 13200 tagagtaaga gggtgccata gttttaagtt atggttcctt aagcgtctta atacatctaa 13260 gttcattgtt tgtccttggg tagtcaatat agattatcat ccaactcata tgaaagccat 13320 attgacttac atggagttga ctactatggg gttagtccat gtagacaaac tatacacaga 13380 ccaaaaacat aaactaaatg atggatttta cacatcaaat ctattttata tcaattataa 13440 tttttcagat aatacacact tgttaactaa acagataaga gtagcaaatt cagagttaat 13500 agataactat aatacattgt atcatccatc tcctgaatct ttagaaagta ttttaaaaag 13560 gtctaatcaa agtaataatg taattgaatt gaaagactat cccatagata aattccaatc 13620 tccaaaggga cggggggtct cagacataac atgcataagc tctaaccaaa aaataaaaca 13680 aggttataac aatcaagatc tgtacaatct atttccagca gtaataatag acaagattgt 13740 agatcattca ggtaacattg caaacatcaa ccaaatgtat acaattactc caaatcaact 13800 tacattaata agtaatggta cttcattata ctgtatgctt ccgtggcatc atataaatag 13860 gtttaatttt gtgtttagct ccactggttg caaaattagt acaaaactta tacttaagga 13920 tcttaaaata aaggatcctc attgtatagc ctttataggg gaaggggcag gaaatttgtt 13980 gttacgcaca gtagtggaat tacatccaga cataaaatat atttatagaa gtctaaaaga 14040 ttgtaatgat catagtttac caattgagtt tctaagatta tacaatggcc atataagtat 14100 agattatgga gaaaatctaa ctataccagc cactgatgca accaatgcta tacattggtc 14160 ttacttacat ataagatatg cagaacccat aaatcttttt gtatgtgatg ctgagttacc 14220 tgatttaact aactggagta gaattgtttc agaatggtat aagcatgtta gatgttgcaa 14280 gtattgctct acaattgacc gaagtaaatt aattgtaaaa tatcatgcac aagatatcac 14340 tgatttcaaa ttaaataaca tatcaatagt caaaacatat gtgtgcttag gtagtaagct 14400 gaaaggttct gaggtttatt tagtccttac agttggtcca tctaatatat ttccatcttt 14460 caatgtagtg cagaatgcta agttgatact ttcaaggaca caaaattttc ccatgcctaa 14520 gaagattgac aaggattcag tagatgcaaa tatcaaaagt ttgataccgt ttctttgtta 14580 tcctataact aagaaaggga taaaggcagc attatctaag ttaaaagatg tggtagatgg 14640 aaacatttta tcatattcta tagcagggcg aaatgaagtt tatagtaaca agcttataaa 14700 ctataaattg ttaaacatcc taaaatggtt agatcatata ttaaattttc gatctctaga 14760 gttcagctat aatcacttat atatgattga atcaacatat cctttcttaa gtgagttact 14820 aaacagtttg actactaatg aacttaaaaa attaattaag gtaacaggga gtgtattata 14880 tagtcttcag catgaattgt aagactcata acactttggt gtgattcatt ttacaaccat 14940 gattatatgt aatgtaatat caatatagtt atttaaaaac tcacattatc tatatagttg 15000 ttaatcttaa attcccacat atctgtgttc caactcaaat tccactggtc aagatctaaa 15060 ccagaaaatc aaaaatttaa tggtacgaga atatgtcctt tatgttgcaa gaggatagtt 15120 tttgatactt tttttctcgt 15140 //