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GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis

Term Information

ID GO:0097200
Name cysteine-type endopeptidase activity involved in execution phase of apoptosis
Ontology Molecular Function
Definition Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis.
Comment Examples of gene products that may be annotated to this term include CASP3, CASP6 and CASP7, also called effector (or executioner) caspases.
GONUTS GO:0097200 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow effector caspase activity
narrow executioner caspase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating cell death and apoptosis using the new guidelinesLink
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0006915 apoptotic process only_in_taxon 33154 Opisthokonta
More information on taxon constraints in GO is available here

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis CONSIDER GO:0097200
GO:0006923 obsolete cleavage of cytoskeletal proteins involved in execution phase of apoptosis CONSIDER GO:0097200
GO:0030972 obsolete cleavage of cytosolic proteins involved in execution phase of apoptosis CONSIDER GO:0097200

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0097200:
Relationship To GO:0097200 Child Term Child Term Name
Regulates GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
Negatively regulates GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
Positively regulates GO:2001272 positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0097200. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0097200 based on the entire annotation set Co-occurrence statistics for GO:0097200 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-06-22 Added RELATION part of GO:0097194 (execution phase of apoptosis)
2013-02-02 Deleted RELATION part of GO:0097194 (execution phase of apoptosis)
2012-10-29 Added RELATION part of GO:0097194 (execution phase of apoptosis)
2012-02-04 Deleted SYNONYM effector caspase
2012-02-04 Added SYNONYM executioner caspase activity
2012-02-04 Added SYNONYM effector caspase activity
2011-12-14 Added RELATION is a GO:0097153 (cysteine-type endopeptidase activity involved in apoptotic process)
2011-12-14 Added SYNONYM effector caspase
2011-12-14 Added TERM cysteine-type endopeptidase activity involved in execution phase of apoptosis
2011-12-14 Added DEFINITION Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis.

Term

Timestamp Action Category Detail
2011-12-14 Added TERM cysteine-type endopeptidase activity involved in execution phase of apoptosis

Definition/synonyms

Timestamp Action Category Detail
2012-02-04 Deleted SYNONYM effector caspase
2012-02-04 Added SYNONYM executioner caspase activity
2012-02-04 Added SYNONYM effector caspase activity
2011-12-14 Added SYNONYM effector caspase
2011-12-14 Added DEFINITION Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis.

Relationships

Timestamp Action Category Detail
2013-06-22 Added RELATION part of GO:0097194 (execution phase of apoptosis)
2013-02-02 Deleted RELATION part of GO:0097194 (execution phase of apoptosis)
2012-10-29 Added RELATION part of GO:0097194 (execution phase of apoptosis)
2011-12-14 Added RELATION is a GO:0097153 (cysteine-type endopeptidase activity involved in apoptotic process)
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