Research

I am a Post-doctoral researcher at the European Bioinformatics Institute in the Thornton Group. I collaborate closely with the experimental groups at the Institute of Healthy Ageing in UCL. My research includes the following themes:

Development of methods for the study of molecular pathways:
- I use logic-based methods to infer the effects of perturbations on pathway maps, with focus on the Insulin/IGF-Like Signalling Pathway. The methods are being implemented in NetEffects.
Integrative analyses of gene expression and chromatin immunoprecipitation high-throughput datasets:
- I work in collaboration with lab scientists to try and characterise the mechanisms of ageing using Drosophila melanogaster and Caenorhabditis elegans mutants. This work involves within or across species analyses


Publications

A complete list of my publications is available on google scholar


Background

Postdoctoral Fellowship 2007-2009:
- University of Cambridge, Department of Oncology and Cambridge Research Institute
Education:
- PhD 2006: Imperial College London, Department of Computing (supervised by Marek Sergot)
- MSc 2002: in Bioinformatics, Imperial College London
- BSc 2001: in Genetics, University College London


Contact

irenep[AT]ebi.ac.uk