The UniProt Protein DAS Server

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The distributed annotation system (DAS) is a client-server system in which a single client integrates information from multiple servers. The UniProt DAS server provides access to sequence and annotation from UniProtKB and UniParc. The server also gives access to Gene Ontology Annotation of UniProt sequences (GOA) and theoretical tryptic digests of protein sequences. Researchers can easily access DAS data through the use of suitable DAS client such as Dasty3 or directly in the XML format provided by the servers.

An extremely useful resource for users of DAS is the DAS Registration Server that supports registry and discovery of DAS services. The data sources provided by the UniProt DAS server are all registered with this service.

Access the UniProt DAS Server

Data sources can be accessed here

The UniProt DAS server is built upon the MyDas Java DAS Server Framework.The primary sources of the data available from the UniProt DAS reference server include: UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, UniParc (The UniProt Archive), and GOA (Gene Ontology annotation of UniProt)

Data Sources

The individual data sources, together with some example queries are presented in the table below:

DSN (Data Source Name) Type Description Coordinate Systems Example Queries
Sequence Request Features Request
uniprot Reference Server UniProtKB UniProtKB Accession numbers e.g. O35502 sequence features
Swiss-Prot ID e.g. A4_HUMAN sequence features
uniparc Reference Server UniProt Archive (UniParc) UniParc ID e.g. UPI0000125656 sequence features
uniprot-tryptic Annotation Server Theoretical tryptic peptides based upon a complete and successful digest of the requested UniProtKB protein with trypsin. UniProtKB Accession numbers e.g. O35502 - features
Swiss-Prot ID e.g. A4_HUMAN - features
uniprot-goa Annotation Server GO Annotation of UniProtKB UniProtKB Accession numbers e.g. P99999 - features
Swiss-Prot ID e.g. A4_HUMAN - features

Project Support

The 'UniProt DAS Service Project' is supported by UniProt team at EBI

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