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General Courses Information |
EBI Affiliated Course - Genome and Protein Functional Annotation with InterPro (IMPACT) 2010Course Summary
Title: Genome and Protein Functional Annotation with InterPro (IMPACT) 2010 Registration Deadline: Closed Course OverviewIMPACT Training Workshop 3InterPro for Functional Annotation - understanding the added value of InterPro's component databasesThis 2-day IMPACT workshop focuses on understanding the InterPro database, how some of the member databases contribute to it and ultimately how InterPro gains from their input. This workshop will provide insights into the biological significance of the results obtained from using a particular database, and into the level of confidence that should be attached to their annotation. This will allow sensible interpretation of what that database tells us about a given family of sequences, and crucially, how this information differs between the databases, and why. Target audienceResearchers using or planning to use InterPro. Learning ObjectivesThis workshop is a valuable opportunity to learn how its component databases add value to InterPro, and hence how InterPro can add value to your analyses. The presentations and tutorials are augmented with user-driven practical sessions, providing further opportunities to explore InterPro with your own 'problem' sequences. Background InformationInterPro is an integrated resource containing annotated signatures for a wide range of protein families. The signatures tend to be diagnostic of particular protein functions or structural features, making them useful tools for characterising unknown sequences, particularly from high-throughput genome sequencing projects. Amongst the original contributor databases were the motif- and domain-based repositories: PROSITE, PRINTS and Pfam. Later, more explicit structural information was added via resources such as Gene3D. Today, InterPro represents an amalgam of 11 databases, each of which provides uniquely specialised insights into the protein families they encode. Each of the partner databases uses a different diagnostic approach: some use single motifs (encoded as 'regular expression' patterns), some exploit multiple-motifs (encoded as 'fingerprints'), and others use complete domains (encoded as HMMs or profiles). Each of these methods performs differently, sometimes in ways that are not obvious to those who don't use them routinely; but these differences are important, as they ultimately determine what we see, and how we interpret our results. Programme
Please follow this link to complete the feedback form for this course. RegistrationThe registration fee for this workshop is £50 and includes lunches and refreshment breaks on all days. You will need to pay for your own travel and accomodation. You will need to pay by credit card as you submit your registration - therefore please have your card to hand. To register for this workshop please use one of the following link (Items marked * are mandatory. Incomplete registrations will not be processed): Registration CLOSED The registration page will give you the option of booking a room at the Travellodge in the centre of Cambridge for an extra £60 charge. This is optional and you are more than welcome to arrange you own accommodation if you would prefer. Please follow the instructions on the registration page to book a room at the Travellodge. Top |
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