This section consists of multiple pages. Use these links to navigate
Why do we need PDBe?
Structural biology continues to have an enormous impact on our understanding of biology and medicine. Three-dimensional structures give us insight into how macromolecules work, and help to explain how their functions are disrupted by mutation or by interaction with small molecules. Biologists are now in a position to combine structural biology with genomics approaches to determine every protein fold encoded by a genome. As these efforts gain momentum, the demand for efficient access to sequence, structure and protein-family information is rising; biologists need standardised ways of viewing and describing proteins so that they can share and use data effectively.
Figure 1 The PDBe homepage provides access to tools and services for depositing, searching, exploring and analysing macromolecular structural data.
Macromolecular structures are complex and therefore advanced tools are needed for their analysis. PDBe’s suite of web-based services allows you to make the most of the global collection of publicly available structural data.
Secondary Structure Matching (SSM) service for comparing and aligning 3D protein structures; search for structures that are similar to that of a reference protein, and visualise superimposed structures.